BIOACTIVITY OF Agaricus bisporus AND Hericium erinaceus MUSHROOMS BY-PRODUCTS
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Hericium erinaceus waste extract stimulated growth of probiotic E. coli Nissle 1917 and pathogenic O157:H7, while Agaricus bisporus extract did not disturb growth of either. The Hericium extract was cytotoxic to HepG2 liver cancer cells, up to 43.1%.
Extracts obtained from Hericium erinaceus (HeE) and Agaricus bisporus (AbE) solid waste were investigated for their capacity to modulate the growth of the probiotic (E. coli Nissle 1917) and foodborne pathogen (E. coli O157:H7) Escherichia strains, and cytotoxic potential against the human hepatocellular carcinoma cell line (HepG2). In selected assays, the tested concentrations did not exceed 1 mg/mL. HeE extract stimulated growth, while AbE extract did not disturb the growth dynamics of both E. coli strains. HeE extract exhibited significant cytotoxicity towards HepG2 cells (up to 43.1%). The obtained results confirmed that not only medicinal and edible mushrooms, but also their by products, could exhibit biological effects.
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