Strain Profile
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Bifidobacterium breve B-3
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Bifidobacterium breve B-3 has been studied primarily in the context of metabolic health, with research spanning animal models and several randomized controlled trials in humans examining body fat and related metabolic outcomes in adults. In vitro work has examined intestinal barrier function, and animal studies have explored metabolic and skin health topics. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 12 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 9 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
15 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
ANIMAL
2022
RCT
2020
ANIMAL
2018
IN_VITRO
2018
RCT
2015
RCT
2015
ANIMAL
2013
ANIMAL
2010
ANIMAL
2025
REVIEW
2025
REVIEW
2025
REVIEW
2023
OTHER
2023
OTHER
2018
RCT
Browse all 15 papers →
Effects of Bifidobacterium breve B-3 on Glycemic Control and Glucose-Regulatory Responses in db/db Mice
· Journal of Microbiology and Biotechnology
Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial
· Nutrients
Heat-Killed Bifidobacterium breve B-3 Enhances Muscle Functions: Possible Involvement of Increases in Muscle Mass and Mitochondrial Biogenesis
· Nutrients
Bioactive factors secreted by Bifidobacterium breve B-3 enhance barrier function in human intestinal Caco-2 cells
· Beneficial Microbes
Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial
· Bioscience of Microbiota Food and Health
Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial
· Journal of Nutritional Science
Effect of Bifidobacterium breve B-3 on skin photoaging induced by chronic UV irradiation in mice
· Beneficial Microbes
Bifidobacterium breve B-3 exerts metabolic syndrome-suppressing effects in the liver of diet-induced obese mice: a DNA microarray analysis
· Beneficial Microbes
Antiobesity Effects of Bifidobacterium breve Strain B-3 Supplementation in a Mouse Model with High-Fat Diet-Induced Obesity
· Bioscience Biotechnology and Biochemistry
The Role of Probiotics in Modulating Gut Microbiota and Metabolic Health for Weight Management: A Mini Review
· Acta Microbiologica Hellenica
(untitled)
· Microbial Science Archives
The Role of Probiotics and Gut Microbiota in Nutrient Metabolism
· Microbial Science Archives
Reply to Lee, S.Y. Comment on “Sung et al. Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial. Nutrients 2023, 15, 28”
· Nutrients
Comment on Sung et al. Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial. Nutrients 2023, 15, 28
· Nutrients
Effect of combined bifidobacteria supplementation and resistance training on cognitive function, body composition and bowel habits of healthy elderly subjects
· Beneficial Microbes
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Citations
Selected papers that name this strain.
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[1]
PMID 42661360 →Effects of Bifidobacterium breve B-3 on Glycemic Control and Glucose-Regulatory Responses in db/db Mice· Journal of Microbiology and Biotechnology · 2026
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[2]
PMID 36615686 →Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial· Nutrients · 2022
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[3]
PMID 30094122 →Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial· Bioscience of Microbiota Food and Health · 2018
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[4]
PMID 26090097 →Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial· Journal of Nutritional Science · 2015
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[5]
PMID 20699581 →Antiobesity Effects of Bifidobacterium breve Strain B-3 Supplementation in a Mouse Model with High-Fat Diet-Induced Obesity· Bioscience Biotechnology and Biochemistry · 2010