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Lacticaseibacillus paracasei CNCM I-1572

◐ Food-origin
Sequenced
Public genome assembly available

Lacticaseibacillus paracasei CNCM I-1572 (commercially known as L. casei DG) has accumulated a body of human clinical research, with multiple randomized controlled trials examining its role in digestive health. RCT and observational research has examined symptom frequency in patients with irritable bowel syndrome and episode frequency in those with colonic diverticular disease (small pouches that can form in the intestinal wall). A 2020 RCT also examined amino acid absorption from plant protein following supplementation. Gastrointestinal transit studies have examined the strain's survival through passage in the gut. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 10 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 4 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

11 papers reference this strain in the probiotic database.

Match confidence
2025 RCT
Postbiotic Supplementation Increases Amino Acid Absorption from Plant-Based Meal: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study
· Probiotics and Antimicrobial Proteins
2025 RCT
Lactobacillus Paracasei CNCM I 1572 is Better than Placebo in Preventing Acute Diverticulitis Occurrence (Revised Manuscript 661a120f-b910-4133-ab7e-4bd3e1713c96)
· Probiotics and Antimicrobial Proteins
2022 REVIEW
Lactobacillus paracasei CNCM I 1572: A Promising Candidate for Management of Colonic Diverticular Disease
· Journal of Clinical Medicine
2021 RCT
Efficacy and safety of Lactobacillus paracasei CNCM I-1572 and fructo- oligosaccharides in the treatment of patients with irritable bowel syndrome with constipation
· Experimental and Clinical Gastroenterology
2021 OBSERVATIONAL
The use of Lactobacillus casei DG® prevents symptomatic episodes and reduces the antibiotic use in patients affected by chronic bacterial prostatitis: results from a phase IV study
· World Journal of Urology
2020 RCT
Probiotic Administration Increases Amino Acid Absorption from Plant Protein: a Placebo-Controlled, Randomized, Double-Blind, Multicenter, Crossover Study
· Probiotics and Antimicrobial Proteins
2019 REVIEW
Analysis of the strain-specifi c eff ects of lactobacilli L. casei DG (L. paracasei CNCM I-1572) and the possibility of their use in clinical practice
· Experimental and Clinical Gastroenterology
2018 OBSERVATIONAL
Quantitative Recovery of Viable Lactobacillus paracasei CNCM I-1572 (L. casei DG®) After Gastrointestinal Passage in Healthy Adults
· Frontiers in Microbiology
2017 RCT
Effect of Lactobacillus paracasei CNCM I‐1572 on symptoms, gut microbiota, short chain fatty acids, and immune activation in patients with irritable bowel syndrome: A pilot randomized clinical trial
· United European Gastroenterology Journal
2016 IN_VITRO
Bacterial stimuli activate nitric oxide colonic mucosal production in diverticular disease. Protective effects of L. casei DG ® (Lactobacillus paracasei CNCM I‐1572)
· United European Gastroenterology Journal
2012 REVIEW
Scientific Opinion on the substantiation of health claims related to Lactobacillus casei DG CNCM I‐1572 and decreasing potentially pathogenic gastro intestinal microorganisms (ID 2949, 3061, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
· EFSA Journal
Browse all 11 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Lactobacillus Paracasei CNCM I 1572 is Better than Placebo in Preventing Acute Diverticulitis Occurrence (Revised Manuscript 661a120f-b910-4133-ab7e-4bd3e1713c96)
    · Probiotics and Antimicrobial Proteins · 2025
    PMID 41105168 →
  2. [2]
    Probiotic Administration Increases Amino Acid Absorption from Plant Protein: a Placebo-Controlled, Randomized, Double-Blind, Multicenter, Crossover Study
    · Probiotics and Antimicrobial Proteins · 2020
    PMID 32358640 →
  3. [3]
    Quantitative Recovery of Viable Lactobacillus paracasei CNCM I-1572 (L. casei DG®) After Gastrointestinal Passage in Healthy Adults
    · Frontiers in Microbiology · 2018
    PMID 30116228 →