Strain Profile
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Lacticaseibacillus paracasei DG
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
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Public genome assembly available
Lacticaseibacillus paracasei DG (also known as L. casei DG, CNCM I-1572) is a strain with documented gastrointestinal survival in healthy adults and a body of clinical and preclinical research. Human research, including an RCT and observational studies, has examined gut microbiota composition and has explored contexts such as Parkinson's disease non-motor symptoms and digestive enzyme function. In vitro work has examined immunomodulatory pathways linked to its exopolysaccharide components. The strain has a documented production history. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 17 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 8 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+3 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
17 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
ANIMAL
2025
REVIEW
2025
OBSERVATIONAL
2025
IN_VITRO
2025
WGS
2024
OBSERVATIONAL
2024
REVIEW
2024
RCT
2023
RCT
2021
ANIMAL
2021
ANIMAL
2020
RCT
2019
REVIEW
2018
OBSERVATIONAL
2016
IN_VITRO
2015
OBSERVATIONAL
2026
IN_VITRO
Browse all 17 papers →
Gut Microbiota Manipulation by Probiotic Lacticaseibacillus paracasei DG I1572 as New Therapeutical Strategy to Counteract Vascular Inflammaging
· Molecular Nutrition & Food Research
The use of oral probiotics in pregnant women as a new paradigm for healthy motherhood: A prospective study
· GYNECOLOGY
Effect of antibacterial and probiotic therapy on the restoration of low fecal elastase levels in patients without imaging findings of pancreatic injuries
· Meditsinskiy sovet = Medical Council
Survival and Impact on Microbial Diversity of Lacticaseibacillus paracasei DG in a Simulation of Human Intestinal Microbial Ecosystem
· Nutrients
Genetic and phenotypic stability of Lacticaseibacillus paracasei DG (DSM 34154) over 10 years of industrial production
· Applied and Environmental Microbiology
Synbiotic supplementation may globally improve non-motor symptoms in patients with stable Parkinson’s disease: results from an open label single-arm study
· Scientific Reports
Functional constipation in children and probiotics: A review
· Pediatrics Consilium Medicum
Collinsella aerofaciens as a predictive marker of response to probiotic treatment in non-constipated irritable bowel syndrome
· Gut Microbes
The effectiveness of the use of synbiotics in the complex therapy of acute intestinal infections in children
· Russian Pediatric Journal
Co-administration of vitamin D3 and Lacticaseibacillus paracasei DG increase 25-hydroxyvitamin D serum levels in mice
· Annals of Microbiology
Probiotics Modulate Mouse Gut Microbiota and Influence Intestinal Immune and Serotonergic Gene Expression in a Site-Specific Fashion
· Frontiers in Microbiology
OVERALL ASSESSMENT OF A MODEL PROBIOTIC BACTERIUM: FROM GUT COLONIZATION TO CLINICAL EFFICACY
· Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)
Analysis of the strain-specifi c eff ects of lactobacilli L. casei DG (L. paracasei CNCM I-1572) and the possibility of their use in clinical practice
· Experimental and Clinical Gastroenterology
Quantitative Recovery of Viable Lactobacillus paracasei CNCM I-1572 (L. casei DG®) After Gastrointestinal Passage in Healthy Adults
· Frontiers in Microbiology
A Novel Rhamnose-Rich Hetero-exopolysaccharide Isolated from Lactobacillus paracasei DG Activates THP-1 Human Monocytic Cells
· Applied and Environmental Microbiology
EXPLORING LACTOBACILLUS PARACASEI PROBIOSIS AND METABOLIC POTENTIAL
· Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)
In vitro assessment of the impact of astragalus, pineapple stem and bergamot extracts on human fecal bacteria
· BMC Complementary Medicine and Therapies
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Citations
Selected papers that name this strain.
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[1]
PMID 41010480 →Survival and Impact on Microbial Diversity of Lacticaseibacillus paracasei DG in a Simulation of Human Intestinal Microbial Ecosystem· Nutrients · 2025
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[2]
PMID 40272178 →Genetic and phenotypic stability of Lacticaseibacillus paracasei DG (DSM 34154) over 10 years of industrial production· Applied and Environmental Microbiology · 2025
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[3]
PMID 30116228 →Quantitative Recovery of Viable Lactobacillus paracasei CNCM I-1572 (L. casei DG®) After Gastrointestinal Passage in Healthy Adults· Frontiers in Microbiology · 2018