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Lactiplantibacillus plantarum P101 A

P101 A
◐ Food-origin
Sequenced
Public genome assembly available

Lactiplantibacillus plantarum P101 (and the closely related P101-A sub-isolate) has been studied extensively in animal models, with a research focus on liver health and gut-liver axis interactions. Multiple mouse studies have examined it in models of alcoholic liver injury, chemical-induced liver damage, heavy metal exposure, and cyclophosphamide-induced oxidative stress, examining gut microbiota composition and signaling pathways such as Nrf2. A 2025 animal study examined this strain in the context of combined microplastic and plasticizer (DEHP) exposure and gut microbiota. In vitro screening has also examined cholesterol metabolism. All studies identified are preclinical; no human clinical trials for this strain were identified in the index. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 13 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 2 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

15 papers reference this strain in the probiotic database.

Match confidence
2026 ANIMAL
Gut-ovary axis mediated synergistic reproductive toxicity of polystyrene nanoplastics and perfluorobutanoic acid co-exposure: pyroptotic signaling and probiotic mitigation
· Particle and Fibre Toxicology
2026 ANIMAL
Utilization of Mature Luffa Cylindrica Resources: Influence of Lactiplantibacillus Plantarum P101 Fermentation on Chemical Composition and Functional Characteristics of Luffa
· Journal of Food Science
2025 ANIMAL
Lactiplantibacillus plantarum P101 Alleviates Liver Toxicity of Combined Microplastics and Di-(2-Ethylhexyl) Phthalate via Regulating Gut Microbiota
· Probiotics and Antimicrobial Proteins
2024 ANIMAL
Exploration of Lactiplantibacillus plantarum P101 ameliorated the alcohol-induced testicular dysfunction based on metabolome analysis
· Food and Chemical Toxicology
2024 ANIMAL
Fermentation of Luffa cylindrica by Lactiplantibacillus plantarum P101 enhanced functional properties: Insights into immune modulation, intestinal barrier repair, and intestinal microbiota regulation
· Food Bioscience
2024 ANIMAL
Lactiplantibacillus plantarum P101 Alleviated Alcohol-Induced Hepatic Lipid Accumulation in Mice via AMPK Signaling Pathway: Gut Microbiota and Metabolomics Analysis
· Probiotics and Antimicrobial Proteins
2024 ANIMAL
Lactiplantibacillus plantarum P101-fermented Luffa cylindrica juice alleviate F-53B-induced liver steatosis in mice via the gut-liver axis
· Food Bioscience
2024 ANIMAL
Lactiplantibacillus plantarum P101 Ameliorates TiO2 NP-Induced Bone Injury in Young Rats by Remodeling the Gut Microbiota and Inhibiting the Production of Pro-Inflammatory Cytokines
· International Journal of Nanomedicine
2023 ANIMAL
Indole-3-acetamide from gut microbiota activated hepatic AhR and mediated the remission effect of Lactiplantibacillus plantarum P101 on alcoholic liver injury in mice
· Food & Function
2023 IN_VITRO
Fermented soy milk with cholesterol-lowering potential: Probiotics screening, physicochemical properties, antioxidant activity and volatile composition
· Food Bioscience
2023 ANIMAL
Lactiplantibacillus plantarum P101 alleviated lead-induced more severe hepatic injury in obese mice, by promoting fecal lead excretion and enhancing antioxidative defense system
· Journal of Applied Microbiology
2023 ANIMAL
Lactiplantibacillus plantarum P101 Attenuated Cyclophosphamide-Induced Liver Injury in Mice by Regulating the Nrf2/ARE Signaling Pathway
· International Journal of Molecular Sciences
2022 ANIMAL
Lactiplantibacillus plantarum P101 alleviates alcoholic liver injury by modulating the Nrf2/HO-1 pathway in mice
· Journal of Applied Microbiology
2022 ANIMAL
The Combination of Epigallocatechin Gallate and Lactiplantibacillus plantarum P101 Alleviated Carbon Tetrachloride-Induced Liver Injury in Mice by Regulating Gut Microbiota
· Applied Sciences
2022 ANIMAL
Combination of Houttuynia cordata polysaccharide and Lactiplantibacillus plantarum P101 alleviates acute liver injury by regulating gut microbiota in mice
· Journal of the Science of Food and Agriculture
Browse all 15 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Gut-ovary axis mediated synergistic reproductive toxicity of polystyrene nanoplastics and perfluorobutanoic acid co-exposure: pyroptotic signaling and probiotic mitigation
    · Particle and Fibre Toxicology · 2026
    PMID 41723513 →
  2. [2]
    Lactiplantibacillus plantarum P101 Alleviates Liver Toxicity of Combined Microplastics and Di-(2-Ethylhexyl) Phthalate via Regulating Gut Microbiota
    · Probiotics and Antimicrobial Proteins · 2025
    PMID 39753940 →
  3. [3]
    Lactiplantibacillus plantarum P101 alleviated lead-induced more severe hepatic injury in obese mice, by promoting fecal lead excretion and enhancing antioxidative defense system
    · Journal of Applied Microbiology · 2023
    PMID 36958864 →