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Ligilactobacillus salivarius LS01

◔ Human-origin
Sequenced
Public genome assembly available

Ligilactobacillus salivarius LS01 (also registered as DSM 22775) has been studied in the context of atopic dermatitis, a chronic inflammatory skin condition, in several randomized, placebo-controlled trials in adults and children. Human trial evidence also extends to pediatric asthma management, where LS01 was evaluated in combination with Bifidobacterium breve B632. In vitro work has examined immunomodulatory activity involving NF-κB and COX-2 pathways in airway inflammation models. Meta-analyses examining probiotics in adult atopic dermatitis provide broader context, though they are not specific to this strain alone. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 9 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 6 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

9 papers reference this strain in the probiotic database.

Match confidence
2025 IN_VITRO
Dose-Dependent Anti-Inflammatory Effects of Live and Heat-Treated Ligilactobacillus salivarius and Bifidobacterium breve via NF-κB and COX-2 Modulation in an In Vitro Model of Airway Inflammation
· Nutrients
2022 RCT
The Probiotics in Pediatric Asthma Management (PROPAM) Study in the Primary Care Setting: A Randomized, Controlled, Double-Blind Trial with Ligilactobacillus salivarius LS01 (DSM 22775) and Bifidobacterium breve B632 (DSM 24706)
· Journal of Immunology Research
2022 META_ANALYSIS
The efficacy of probiotics supplementation for the treatment of atopic dermatitis in adults: a systematic review and meta-analysis
· Journal of Dermatological Treatment
2015 IN_VITRO
Immunomodulatory Effects of Lactobacillus salivarius LS01 and Bifidobacterium breve BR03, Alone and in Combination, on Peripheral Blood Mononuclear Cells of Allergic Asthmatics
· Allergy Asthma and Immunology Research
2014 RCT
Treatment of Atopic Dermatitis Eczema With a High Concentration of Lactobacillus salivarius LS01 Associated With an Innovative Gelling Complex
· Journal of Clinical Gastroenterology
2014 OBSERVATIONAL
Preliminary Results on Clinical Effects of Probiotic Lactobacillus salivarius LS01 in Children Affected by Atopic Dermatitis
· Journal of Clinical Gastroenterology
2012 RCT
Changing of Fecal Flora and Clinical Effect of L. salivarius LS01 in Adults With Atopic Dermatitis
· Journal of Clinical Gastroenterology
2011 RCT
Effects of Lactobacillus Salivarius LS01 (DSM 22775) Treatment on Adult Atopic Dermatitis: A Randomized Placebo-Controlled Study
· International Journal of Immunopathology and Pharmacology
2025 META_ANALYSIS
Effects of Probiotic Supplementation in Adults with Atopic Dermatitis: A Meta-Analysis
· Journal of Dermatology Research
Browse all 9 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    The efficacy of probiotics supplementation for the treatment of atopic dermatitis in adults: a systematic review and meta-analysis
    · Journal of Dermatological Treatment · 2022
    PMID 35670101 →
  2. [2]
    Preliminary Results on Clinical Effects of Probiotic Lactobacillus salivarius LS01 in Children Affected by Atopic Dermatitis
    · Journal of Clinical Gastroenterology · 2014
    PMID 25291124 →
  3. [3]
    Treatment of Atopic Dermatitis Eczema With a High Concentration of Lactobacillus salivarius LS01 Associated With an Innovative Gelling Complex
    · Journal of Clinical Gastroenterology · 2014
    PMID 25291127 →
  4. [4]
    Changing of Fecal Flora and Clinical Effect of L. salivarius LS01 in Adults With Atopic Dermatitis
    · Journal of Clinical Gastroenterology · 2012
    PMID 22955359 →
  5. [5]
    Effects of Lactobacillus Salivarius LS01 (DSM 22775) Treatment on Adult Atopic Dermatitis: A Randomized Placebo-Controlled Study
    · International Journal of Immunopathology and Pharmacology · 2011
    PMID 22230409 →