Strain Profile
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Ligilactobacillus salivarius
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Ligilactobacillus salivarius (species-level entry, no specific strain designation) is an oral and intestinal lactic acid bacterium studied across several strains for immune modulation and respiratory health. A randomized controlled trial examined L. salivarius LS01 in children with asthma, and animal studies have examined long-term protection outcomes against Streptococcus pneumoniae in certain strains. An observational report examined immune and nutritional markers in elderly nursing home residents given another strain during the COVID-19 pandemic. Because the linked evidence spans multiple distinct strains, strain-specific conclusions cannot be drawn; the species has been studied in immune and respiratory contexts, but human evidence remains preliminary and strain-dependent. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 333 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 93 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
470 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
IN_VITRO
2026
IN_VITRO
2026
WGS
2026
OTHER
2026
ANIMAL
2026
ANIMAL
2026
IN_VITRO
2026
OTHER
2026
REVIEW
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
RCT
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
IN_VITRO
2026
ANIMAL
2026
IN_VITRO
Browse all 470 papers →
Enhanced eradicative effects of postbiotics derived from Ligilactobacillus salivarius LSA-6 combined with cold plasma against Listeria monocytogenes biofilms for fresh produce preservation
· Food Bioscience
Animal-sourced probiotic bacteria induce interferon gamma in humans and mice
· In Silico Research in Biomedicine
Probiotic properties of Ligilactobacillus salivarius K611 isolated from chicken feces and its antibacterial activity against Salmonella Typhimurium
· Journal of Agriculture and Food Research
MassIVE MSV000100444 - Untargeted Metabolomics of Human Fecal Samples Associated with Anti-PD-1 Response and Ligilactobacillus salivarius Culture Supernatants
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Targeting microbiota-generated acetaldehyde to prevent progression of metabolic dysfunction-associated steatotic liver disease
· Cell Metabolism
Bacterial vesicles from intratumoral L. salivarius enhance PD-1 blockade via FPR1-mediated macrophage polarization in gastric cancer
· Cell Reports Medicine
Impact of selenium-enriched Ligilactobacillus salivarius DACN818 on Zhacai: Insights from metabolomics and microbiomics
· Food Chemistry X
Use of Ligilactobacillus salivarius SP36 as an Adjunct Culture by an Artisan Dairy and Isolation of New Autochthonous Strains with Technological Potential for Cheesemaking
· Foods
The Role of Probiotics Limosilactobacillus reuteri, Ligilactobacillus salivarius, and Lactobacillus johnsonii in Inhibziting Pathogens, Maintaining Gut Health, and Improving Disease Outcomes
· International Journal of Molecular Sciences
From Macromolecule to Microbe: Identification of Ligilactobacillus salivarius D3-8 as a Key Degrader of Ejiao and a Novel Therapeutic Probiotic for Ulcerative Colitis
· Nutrients
Feline-Derived Ligilactobacillus agilis ZY25 and Ligilactobacillus salivarius ZY35 Alleviate Enteropathogenic Escherichia coli-Induced Intestinal Injury and Microbial Dysbiosis in Mice
· Microorganisms
A novel bile salt hydrolase-producing Ligilactobacillus salivarius prevents diet-induced obesity via regulation of bile acid metabolism and glucagon-like peptide 1 restoration
· Gut Microbes
Probiotic-Containing Nanofiber-Based Dental Floss Suppresses Subgingival Red Complex Periopathogens: A Randomized Double-Blind Crossover Trial
· Probiotics and Antimicrobial Proteins
Effects of Ligilactobacillus salivarius on the control of pullorum disease and cecal microbiota in red-feathered native chickens
· Poultry Science
Ligilactobacillus salivarius Li01 enhances gut microbiota-derived indole-3-propionic acid to alleviate 5-fluorouracil-induced diarrhea in mice
· Food & Function
Intratumoral delivery of probiotic Ligilactobacillus salivarius H22A013 modulates the melanoma microenvironment and enhances trametinib efficacy
· BMC Microbiology
Behavioral, antioxidant, and kynurenine pathway modulation of a specific strain of Ligilactobacillus salivarius in a preclinical model of depression
· European Journal of Nutrition
Ekstrakcija zelenog čaja i fermentacija ekstrakata pomoću Ligilactobacillus salivarius i Lactiplantibacillus plantarum
· TechnoRep (University of Belgrade – Faculty of Technology and Metallurgy)
Ligilactobacillus salivarius 8-2 attenuates intestinal mucosal injury in chicks via the mitochondrial fision-glycometabolism reprogramming axis
· Poultry Science
Biosynthesis of Selenium Nanoparticles by Ligilactobacillus salivarius DACN818: Characterization and Mechanism
· Journal of Agricultural and Food Chemistry
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →Probiotic supplementation improves quality of life and modulates oestradiol in women with endometriosis: a randomised double-blind pilot trial· Figshare · 2026
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[2]
PMID 41484513 →Probiotic-Containing Nanofiber-Based Dental Floss Suppresses Subgingival Red Complex Periopathogens: A Randomized Double-Blind Crossover Trial· Probiotics and Antimicrobial Proteins · 2026
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[3]
PMID 40739452 →Correction: Assessing the Efficacy of Ligilactobacillus salivarius CLS0420 and Lacticaseibacillus paracasei CLPC0603 on Vaginal Well-Being in Healthy Women: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial· Probiotics and Antimicrobial Proteins · 2025
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[4]
PMID 40507130 →Ligilactobacillus salivarius CECT5713 Increases Term Pregnancies in Women with Infertility of Unknown Origin: A Randomized, Triple-Blind, Placebo-Controlled Trial· Nutrients · 2025
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[5]
PMID 38540885 →Understanding Ligilactobacillus salivarius from Probiotic Properties to Omics Technology: A Review· Foods · 2024
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[6]
PMID 38955352 →Ligilactobacillus salivarius V4II-90 eradicates Group B Streptococcus colonisation during pregnancy: a randomised, double-blind, placebo-controlled trial· Beneficial Microbes · 2024
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[7]
PMID 39023333 →Effect of tablets containing a paraprobiotic strain and the cranberry extract on caries incidence in preschool children: A randomized controlled trial· Dental and Medical Problems · 2024
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[8]
PMID 37953676 →Ligilactobacillus salivarius CCFM 1266 modulates gut microbiota and GPR109a-mediated immune suppression to attenuate immune checkpoint blockade-induced colitis· Food & Function · 2023
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[9]
PMID 36865781 →A randomized pilot trial assessing the reduction of gout episodes in hyperuricemic patients by oral administration of Ligilactobacillus salivarius CECT 30632, a strain with the ability to degrade purines· Frontiers in Microbiology · 2023
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[10]
PMID 37007532 →Assessment of the safety and probiotic characteristics of Lactobacillus salivarius CGMCC20700 based on whole-genome sequencing and phenotypic analysis· Frontiers in Microbiology · 2023