Strain Profile · NCBI Strain Taxon 557433
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Limosilactobacillus reuteri JCM 1112

◔ Human-origin
Sequenced
Public genome assembly available

Limosilactobacillus reuteri JCM 1112 is a reference quality sequenced strain of a species widely distributed across mammalian guts, and its metabolic capabilities, including cobalamin (vitamin B12) and reuterin biosynthesis as well as nicotinamide mononucleotide production, have been characterized through whole genome analysis and in vitro studies. An animal study examined glucose metabolism in the context of chronic acrylamide exposure in rodents, including bile acid signaling and antioxidant pathways. Adhesion proteins such as mucus-binding proteins and glyceraldehyde-3-phosphate dehydrogenase, associated with intestinal colonization in laboratory studies, have been structurally characterized. Strain-specific human clinical evidence for JCM 1112 is limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 8 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 2 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

22 papers reference this strain in the probiotic database.

Match confidence
2024 ANIMAL
Lactobacillus reuteri JCM 1112 ameliorates chronic acrylamide-induced glucose metabolism disorder via the bile acid–TGR5–GLP-1 axis and modulates intestinal oxidative stress in mice
· Food & Function
2014 IN_VITRO
Structural and molecular insights into novel surface‐exposed mucus adhesins from Lactobacillus reuteri human strains
· Molecular Microbiology
2025 IN_VITRO
Nicotinamide mononucleotide production by non-recombinant Limosilactobacillus reuteri and nicotinamide adenine dinucleotide synthesizing lactic acid bacteria
· Microbiology Spectrum
2019 IN_VITRO
A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· Microbial Cell Factories
2019 WGS
A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· bioRxiv (Cold Spring Harbor Laboratory)
2018 ANIMAL
Effect of Lactobacillus strains on thymus and chemokine expression in keratinocytes and development of atopic dermatitis-like symptoms
· Beneficial Microbes
2015 IN_VITRO
Lactobacillus reuteri glyceraldehyde-3-phosphate dehydrogenase functions in adhesion to intestinal epithelial cells
· Canadian Journal of Microbiology
2010 ANIMAL
Protective effect of Lactobacillus casei strain Shirota against lethal infection with multi-drug resistant Salmonella enterica serovar Typhimurium DT104 in mice
· Journal of Applied Microbiology
2008 WGS
Comparative Genome Analysis of Lactobacillus reuteri and Lactobacillus fermentum Reveal a Genomic Island for Reuterin and Cobalamin Production
· DNA Research
2008 WGS
Comparative genomics of Lactobacillus originated from intestines of thoroughbred and human by mutation manning
· Institutional Repositories DataBase (IRDB)
2007 WGS
Complete sequence, comparative genomics and post-genome analysis of lactic acid bacteria : No. 4
· Institutional Repositories DataBase (IRDB)
2001 ANIMAL
Antimicrobial Activity of Intraurethrally Administered Probiotic Lactobacillus casei in a Murine Model of Escherichia coli Urinary Tract Infection
· Antimicrobial Agents and Chemotherapy
2021 IN_VITRO
Two-species community design of lactic acid bacteria for optimal production of lactate
· Computational and Structural Biotechnology Journal
2019 OTHER
MOESM1 of A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· Figshare
2019 OTHER
MOESM8 of A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· Figshare
2019 OTHER
MOESM6 of A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· Figshare
2019 OTHER
MOESM3 of A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· Figshare
2019 IN_VITRO
Suppression of lactate production in fed-batch culture of some lactic acid bacteria with sucrose as the carbon source
· Journal of Bioscience and Bioengineering
2019 WGS
MOESM2 of A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· Figshare
2019 OTHER
MOESM5 of A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory
· Figshare
Browse all 22 papers →

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