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Bacillus firmus

◑ Environmental

Sequenced

Public genome assembly available

Bacillus firmus is an alkaliphilic, spore-forming soil bacterium studied primarily in industrial biotechnology contexts, including enzyme production (xylanases, nucleases, cyclomaltodextrin glucanotransferases) and agricultural biocontrol — one in vitro study showed activity against plant-parasitic nematodes. Some older papers describe basic bioenergetics of its ATP synthase. Notably, one in vitro paper documented heat-stable toxin production by B. firmus alongside related Bacillus species, which is a food safety concern relevant to the genus. Probiotic characterization for B. firmus specific to human health is not established in the associated literature, and safety considerations for this species in human use have not been resolved in the available evidence.

Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →

Share of this strain's 56 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Immune 31 papers · 55%

Gut 22 papers · 39%

Respiratory 10 papers · 18%

Brain & Mood 2 papers · 4%

Metabolic 2 papers · 4%

Cardiovascular 1 paper · 2%

+1 more systems

Liver 1 paper · 2%

Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →

Share of this strain's 11 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Respiratory infections 6 papers · 55%

Weight & obesity 4 papers · 36%

High cholesterol 1 paper · 9%

Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →

436 papers reference this strain in the probiotic database.

Match confidence

ANALYSIS OF SALINITY TOLERANCE OF HALOXYLON APHYLLUM BASED ON HALOTOLERANT PLANT GROWTH-PROMOTING RHIZOBACTERIA

· Zenodo (CERN European Organization for Nuclear Research)

Efecto de la incorporación de un soporte inerte para la producción de poli-3-hidroxibutirato (PHB) por fermentación a partir de cascarilla de cacao

Membrane-protein-based insights into anthracene degradation by Bacillus firmus and its enhancement by rhamnolipids

· Journal of Applied Microbiology

2025 OBSERVATIONAL

Detection and Analysis of Drug and Disinfectant Resistance Genes in the Sewage of a Center for Disease Control and Prevention

· Infection and Drug Resistance

Optimization of Extracellular Alkaline Protease Production by Bacillus firmus LE02, Isolated from a Ponyfish, Leiognathus equula

· Research Journal of Pharmacy and Technology

Biotransformation of Hexavalent Chromium from Wastewater Using Bacillus firmus

· Journal of Water Chemistry and Technology

Produção da enzima ciclodextrina glicosil transferase de Bacillus firmus cepa 37 em Escherichia coli

· LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Pengembangan Metode Analisis Sitrinin dan Upaya Penurunan Produksi Sitrinin dalam Fermentasi Cair Monascus purpureus

· JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X

Characterization of a novel MgtE homolog and its structural dynamics in membrane mimetics

· Biophysical Journal

Optimasi Kondisi Inkubasi Kultur (Suhu dan Agitasi) Terhadap Pertumbuhan dan Aktivitas Protease Ektraseluler Bakteri Bacillus firmus Asosiasi Sponge (Porifera: Demospongiae) dari Nusa Lembongan Bali Indonesia

· Journal of Marine Research

Bioconversion of isoeugenol to vanillin by bacillus firmus strain JAA1

· Research Journal of Biotechnology

Optimasi Substrat Dan Pemilihan Co-Substrat Media Kultur Yang Sesuai Terhadap Pertumbuhan Dan Aktivitas Protease Ektraseluler Bakteri Bacillus Firmus Dari Perairan Nusa Lembongan Bali, Indonesia

· Journal of Marine Research

Exploring the Probiotic and Plant Growth Promoting Potential of Endophytic Bacteria Isolated from the Vegetable Crop Bhendi Abelmoschus esculentus

· Ecology Environment and Conservation

Optimasi pH Dan Salinitas Media Kultur Terhadap Pertumbuhan Dan Aktivitas Protease Ektraseluler Bakteri Bacillus Firmus Dari Ekosistem Padang Lamun Nusa Lembongan – Bali.

· Journal of Tropical Marine Science

Use of Bacillus firmus to control nematodes in soybean crops

· Institutional Repository of the Federal Technological University of Paraná (RIUT) (Federal University of Technology – Paraná)

Effect of cultivation media and temperature on metabolite profiles of three nematicidal Bacillus species

· Nematology

TECNOLOGÍA FERMENTATIVA DEL BACILLUS FIRMUS COMO PROBIÓTICO PARA EL CULTIVO DE CAMARONES

· Zenodo (CERN European Organization for Nuclear Research)

Production, Purification, and Characterization of Extracellular Alkaline Protease From Bacillus Firmus Var. Arosia NCIB 10557

· Research Square

Bacillus firmus I-1582 promotes plant growth and impairs infection and development of the cyst nematode Heterodera schachtii over two generations

· Scientific Reports

Identification of Multi-Potent Protein Subtilisin A from halophilic bacterium Bacillus firmus VE2

· Microbial Pathogenesis

Browse all 436 papers →

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