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Bacillus velezensis

◑ Environmental
Sequenced
Public genome assembly available

Bacillus velezensis (species-level, undesignated strain) is a spore-forming soil bacterium studied primarily for agricultural biocontrol applications, including antifungal and antibacterial activity against crop pathogens. The indexed research for this entry spans plant growth promotion, production of lipopeptides with antimicrobial properties, and a 2025 in vitro and C. elegans model study in the context of post-weaning diarrhea pathogens in piglets. A regulatory safety and efficacy assessment by EFSA covers one designated strain (DSM 15544) for use in dairy ruminant feed. Human probiotic evidence is absent for this species-level entry. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 345 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+5 more systems

Symptoms in the research

Share of this strain's 56 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+4 more symptoms

Strains of this species

7 strains of Bacillus velezensis in the index, with 15 linked papers between them.

Bacillus velezensis A2

DEP A2

Bacillus velezensis A2 is a spore-forming soil bacterium whose research record is focused on a specific niche: zearalenone, a mycotoxin (mold-derived toxic compound) that can contaminate animal feed.

Barrier Immune Metabolic
◑ Environmental
7 papers 0 comments

Bacillus velezensis MT9

DEP MT9

Bacillus velezensis MT9 is a marine bacterium that has been studied for its interaction with synthetic polymers.

Metabolic Adhesion Microplastics
◑ Environmental
3 papers 0 comments

Bacillus velezensis EBL50

DEP EBL50

Bacillus velezensis EBL50 is a bacterial strain that has been studied in the context of environmental bioremediation rather than human probiotic use.

Adhesion Metabolic Microplastics
◑ Environmental
1 papers 0 comments

Bacillus velezensis GUIA

DEP GUIA

Bacillus velezensis GUIA is a designated strain of B.

◑ Environmental
0 papers 0 comments

Bacillus velezensis P63

DEP P63

Bacillus velezensis P63 belongs to a species known for producing diverse antimicrobial and bioactive compounds, with applications in both agricultural biocontrol and, to a lesser extent, aquaculture probiotics.

◑ Environmental
1 papers 0 comments

Bacillus velezensis C5

DEP C5

Bacillus velezensis C5 is an environmental isolate studied in the context of polyethylene plastic biodegradation, including research on its adaptive survival mechanisms on microplastic surfaces and chemically enhanced de…

Microplastics Metabolic Survival
◑ Environmental
3 papers 0 comments

Bacillus velezensis CMC-6 R

CMC-6 R

Bacillus velezensis CMC-6-R is a strain of B.

◑ Environmental
0 papers 0 comments

Research

2030 papers reference this strain in the probiotic database.

Match confidence
2026 WGS
Complete genome sequence of biocontrol Bacillus velezensis strain F68 isolated from tomato rhizosphere soil
· Microbiology Resource Announcements
2026 IN_VITRO
Optimization of Pectinase Production from Bacillus velezensis Isolated from Agro-waste using Response Surface Methodology
· Journal of Pure and Applied Microbiology
2026 IN_VITRO
Insight into novel biochemical features and function of novel antifungal GH16-β-glucanase from Bacillus velezensis
· International Journal of Biological Macromolecules
2026 ANIMAL
Genophenotypic insights into biocontrol and growth-promoting mechanisms of Bacillus velezensis BV25 against tomato Fusarium wilt
· BMC Microbiology
2026 ANIMAL
Bacillus velezensis alleviates PM2.5-induced intestinal injury and dysbiosis in broilers via the “lung-gut axis”
· Animal Microbiome
2026 ANIMAL
Divergent ecological strategies of Bacillus velezensis Bac2 and Bacillus subtilis Bac1 Drive biocontrol of cucumber fusarium wilt
· Biological Control
2026 OTHER
Extraction and Identification of Antimicrobial Compounds from Novel Bacillus velezensis OUC-BV1 Guided by Genome Prospecting
· Journal of Ocean University of China
2026 IN_VITRO
In vitro effects of Bacillus velezensis strain Mandacaium against Xanthomonas citri pv. glycines: genomic and metabolomic insights
· Scientific Reports
2026 IN_VITRO
Bacillus velezensis HAB-2 enhances rubber tree seedling growth and induces resistance to foliar diseases
· Applied Soil Ecology
2026 IN_VITRO
Characterization and Biocontrol Potential of Bacillus velezensis FB-4 Against Valsa Canker of Korla Fragrant Pear
· Journal of Fungi
2026 OTHER
Comparative proteomic analysis reveals the modulation of probiotic features in Bacillus velezensis P45 growing on prebiotics and mucin
· Next research.
2026 IN_VITRO
Metabolite profiling of Bacillus velezensis DM extract linked to the rhizosphere of Datura metel L. and dermatoprotective potential of an isolated glycoglycerolipid
· Figshare
2026 IN_VITRO
Biocontrol Efficacy and Mechanisms of Bacillus velezensis AP6 Against Brown Rot in Yam by Fusarium solani
· Journal of Fungi
2026 IN_VITRO
Biocontrol potential and mechanism of endophytic Bacillus velezensis WSR1 against rubber tree anthracnose
· Plant Disease
2026 IN_VITRO
92. Outperforming Probiotic Rivals: Bacillus Velezensis Consortium Leads in Gut Adhesion and Inflammation Control
· Journal of Animal Science
2026 IN_VITRO
Surfactin-Producing Bacillus velezensis A1 Inhibits Lactic Acid Bacteria in Jiang-Flavor Baijiu Fermentation
· Foods
2026 IN_VITRO
The Biocontrol Effect and Induced Disease Resistance Mechanism of Bacillus velezensis FJ17-4 on Cucumber Fusarium Wilt
· Agronomy
2026 IN_VITRO
Influence of a Bacillus velezensis–Based Biostimulant on French Marigold Growth under Different Phosphorus Levels
· HortTechnology
2026 OTHER
Synergistic Effects of Bacillus velezensis and Indole Acetic Acid on Alkaloids Pathway in Catharanthus roseus
· Egyptian Academic Journal of Biological Sciences, H. Botany/Egyptian Academic Journal of Biological Sciences, H. Botany
2026 IN_VITRO
Functional Effects of Bacillus velezensis Metabolites on Barrier Formation, Cytokine Responses, and Phagocytic Activity in Canine Epithelial and Immune Cells
· International Journal of Molecular Sciences
Browse all 2,030 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Bacillus velezensis mitigates chronic LPS-induced lung injury of broilers via microbiota-driven isoflavone production and NF-κB/PPAR-γ axis modulation
    · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · 2026
    PMID 42093011 →
  2. [2]
    Dietary supplementation with Bacillus velezensis enhances the intestinal health of broiler chickens challenged with necrotic enteritis via reshaping the structure and function of the intestinal flora
    · Poultry Science · 2026
    PMID 42035530 →
  3. [3]
    Antagonistic activity of Bacillus velezensis L09 isolated from crocodile gut against Aeromonas dhakensis: Mechanisms and potential for aquaculture applications
    · Water Biology and Security · 2025
    Source →
  4. [4]
    Bacillus velezensis inhibits azoxymethane/dextran sulphate sodium induced colitis associated colorectal cancer via the small molecule HeLM
    · Journal of Gastrointestinal Oncology · 2025
    PMID 40386616 →
  5. [5]
    A novel subtilisin-producing Bacillus velezensis strain (BV-OLS1101) improves growth and mucosal immunity in broiler chickens under Clostridium perfringens challenge
    · Poultry Science · 2025
    PMID 40913980 →
  6. [6]
    Bacillus velezensis CML532 supplementation improved growth performance, protein digestion, and gut health in broilers fed with corn-miscellaneous meal-based low-protein diets
    · Animal nutrition · 2025
    PMID 41716821 →
  7. [7]
    Dietary Supplementation with the Probiotic Bacillus velezensis BV379 Decreases Abdominal Bloating Without Perturbing the Commensal Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled Trial in Healthy Adults
    · Journal of the American Nutrition Association · 2025
    PMID 41025937 →
  8. [8]
    Exploring Bacillus velezensis in a biomedical context: a systematic review
    · Academia molecular biology and genomics. · 2025
    Source →
  9. [9]
    Safety and efficacy of a feed additive consisting of protease and Bacillus velezensisNRRL B-50508, B. velezensisNRRL B-50509 and B. subtilisNRRL B-50510 (Syncra® SWI 201 TPT) for pigs for fattening and other growing porcine species (Danisco (UK) ltd.)
    · Utrecht University Repository (Utrecht University) · 2025
    Source →
  10. [10]
    Activation of aryl hydrocarbon receptor signaling by indole-3-lactic acid from Bacillus velezensis DS2 reinforces gut mucosal immunity and attenuates inflammaging in aged mice
    · Immunity & Ageing · 2025
    PMID 41456030 →