Strain Profile · NCBI Strain Taxon 321967
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Lactobacillus casei ATCC 334

◐ Food-origin
Sequenced
Public genome assembly available

Lactobacillus casei ATCC 334 is a well-characterized reference strain widely used in laboratory research to study probiotic biology, fermentation, and food technology. In vitro studies have examined its cholesterol oxidation product-binding capacity and its interactions with intestinal immune cells, including cytokine-related signaling in human mucosal tissue models. One animal study examined a related L. casei polysaccharide-peptidoglycan component in a murine model of inflammatory bowel disease. Much of the strain-specific evidence is early-stage or in vitro, and human clinical data for this particular strain are limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 21 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 4 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

80 papers reference this strain in the probiotic database.

Match confidence
2025 IN_VITRO
Effect of Ultrasonication on the Physicochemical Properties and Stability of a Fermented Almond Beverage Added With Microencapsulated Lacticaseibacillus casei ATCC 334
· Journal of Food Processing and Preservation
2024 IN_VITRO
The effect of incorporating microencapsulated Lactobacillus casei ATCC 334 on the physicochemical and rheological properties of fortified Greek‐style yoghurt
· International Journal of Dairy Technology
2024 OTHER
Enhanced preservation of viability and species stratification in Lacticaseibacillus group using levan-fortified skim milk as a cryoprotectant during freeze-drying
· Food Science and Biotechnology
2022 IN_VITRO
Drink with probiotic potential based on water-soluble extract from cashew nuts
· Ciência Rural
2021 IN_VITRO
Strategies for Increased Lactic Acid Production from Algal Cake Fermentations at Low pH by Lactobacillus casei
· Digital Commons - USU (Utah State University)
2021 IN_VITRO
Fermentation Parameters of Suero Costeño Elaborated with Lactic Acid Bacteria Strains
· Current Research in Nutrition and Food Science Journal
2020 IN_VITRO
Specific Gaseous Conditions Significantly Improve Lactobacillus casei and Escherichia coli Survival to Freeze Drying and Rehydration
· HAL (Le Centre pour la Communication Scientifique Directe)
2019 IN_VITRO
Wiązanie cholesterolu przez bakterie fermentacji mlekowej izolowane od dzieci
· Żywność
2017 IN_VITRO
Transient MutS-Based Hypermutation System for Adaptive Evolution of Lactobacillus casei to Low pH
· Applied and Environmental Microbiology
2016 IN_VITRO
Determinación de producción de bacteriocinas a partir de Lactobacillus casei
·
2016 IN_VITRO
EVALUATION OF PROBITOIC POTENTIAL OF LACTOBACILLUS STRAINS FROM FERMENTED FOODS AND FEACES OF INFANTS
· Vietnam Journal of Science and Technology/Science and Technology
2014 IN_VITRO
Evaluation of Modified Amaranth Starch as Shell Material for Encapsulation of Probiotics
· Cereal Chemistry
2014 IN_VITRO
High efficiency electrotransformation of Lactobacillus casei
· FEMS Microbiology Letters
2014 WGS
Genome –Scale Reconstruction of Metabolic Networks of Lactobacillus casei ATCC 334 and 12A
· PLoS ONE
2013 IN_VITRO
Assessment of in vitro removal of cholesterol oxidation products by Lactobacillus casei ATCC334
· Letters in Applied Microbiology
2013 WGS
Genomic Adaptation of the Lactobacillus casei Group
· PLoS ONE
2013 IN_VITRO
Ca 2+-Citrate Uptake and Metabolism in Lactobacillus casei ATCC 334
· Applied and Environmental Microbiology
2013 IN_VITRO
Interaction with Intestinal Epithelial Cells Promotes an Immunosuppressive Phenotype in Lactobacillus casei
· PLoS ONE
2011 IN_VITRO
Investigation of Biomarkers of Bile Tolerance in Lactobacillus casei Using Comparative Proteomics
· Journal of Proteome Research
2010 IN_VITRO
Physiological and Transcriptional Response of Lactobacillus casei ATCC 334 to Acid Stress
· Journal of Bacteriology
Browse all 80 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Anti-Inflammatory Potential of Levilactobacillus brevis LBH1070 and Its Synbiotic in a Murine Model of Experimental Arthritis
    · Microorganisms · 2026
    PMID 42513979 →
  2. [2]
    Assessment of in vitro removal of cholesterol oxidation products by Lactobacillus casei ATCC334
    · Letters in Applied Microbiology · 2013
    PMID 23848962 →