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Lacticaseibacillus casei Zhang

◐ Food-origin
Sequenced
Public genome assembly available

Lacticaseibacillus casei Zhang (formerly Lactobacillus casei Zhang), originally isolated from traditional Mongolian fermented dairy, has been studied across a range of animal models examining gut health, immune function, and metabolic parameters. Animal research has examined intestinal mucosal integrity, immune markers in gut-associated lymphoid tissue, and lipid metabolism in hypercholesterolemic models. One in vitro study examined binding of microcystin-LR, a cyanobacterial toxin, though this has not been evaluated in humans. All available strain-specific evidence originates from in vitro and animal studies; human clinical trial data for L. casei Zhang specifically have not been identified in this index. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 33 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+1 more systems

Symptoms in the research

Share of this strain's 7 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+1 more symptoms

Research

75 papers reference this strain in the probiotic database.

Match confidence
2022 ANIMAL
Inhibition of GABAAR or Application of Lactobacillus casei Zhang Alleviates Ulcerative Colitis in Mice: GABAAR as a Potential Target for Intestinal Epithelial Renewal and Repair
· International Journal of Molecular Sciences
2021 ANIMAL
FC 083PROBIOTIC L.CASEI ZHANG SLOWS THE PROGRESSION OF ACUTE AND CHRONIC KIDNEY DISEASE
· Nephrology Dialysis Transplantation
2021 ANIMAL
Lactobacillus casei Zhang exerts probiotic effects to antibiotic-treated rats
· Computational and Structural Biotechnology Journal
2019 ANIMAL
Lactobacillus casei Zhang Prevents Jejunal Epithelial Damage to Early-Weaned Piglets Induced by Escherichia coli K88 via Regulation of Intestinal Mucosal Integrity, Tight Junction Proteins and Immune Factor Expression
· Journal of Microbiology and Biotechnology
2017 ANIMAL
Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis in mice via adiponectin-elevated different signaling pathways
· Oncotarget
2017 IN_VITRO
Protective effect of surface layer proteins isolated from four Lactobacillus strains on hydrogen-peroxide-induced HT-29 cells oxidative stress
· International Journal of Biological Macromolecules
2016 ANIMAL
Protective Effects of Probiotic Lactobacillus casei Zhang on Chronic Alcoholic Liver Disease in Rats and Its Effects on the Expression of Hepatic Cytochrome P450 3A1/2 and Cytochrome c
· Journal of food and nutrition research
2014 IN_VITRO
EFFECTS OF PROBIOTIC Lactobacillus casei Zhang ON THE EXPRESSION OF iNOS/NO IN RAW264.7CELLS AND RELATED MECHANISMS
· Journal of Inner Mongolia Agricultural University
2011 IN_VITRO
Response of Lactobacillus casei to short bile salts exposure revealed by two-dimensional electrophoresis
·
2011 ANIMAL
Lactobacillus casei Zhang stimulates lipid metabolism in hypercholesterolemic rats by affecting gene expression in the liver
· European Journal of Lipid Science and Technology
2010 ANIMAL
Effect of L. casei Zhang PG on the Phagocytic Function of Mouse Macrophages
L. casei Zhang PG对小鼠巨噬细胞吞噬功能的影响
· 青海医学院学报
2010 IN_VITRO
[Removal of microcystin-LR by lactic acid bacteria].
· PubMed
2009 ANIMAL
Influence of Lactobacillus casei Zhang on immunological function of intestinal mucosa associated lymphoid tissues of mice.
· Acta Nutrimenta Sinica
2009 ANIMAL
Effects of L. casei Zhang on ati-oxidative ability in rats.
· Acta Nutrimenta Sinica
2006 ANIMAL
Study on the influence of IgG in serum and SIgA in the gut of mice after oral lactobacillus
· Heilongjiang xumu shouyi
2026 ANIMAL
Lacticaseibacillus casei Zhang modulates iron homeostasis in iron-overloaded mice via an IL-22-dependent pathways
· npj Science of Food
2024 ANIMAL
Integrated oral microgel system ameliorates renal fibrosis by hitchhiking co-delivery and targeted gut flora modulation
· Journal of Nanobiotechnology
2023 IN_VITRO
Rapid Detection of the Activity of Lacticaseibacillus Casei Zhang by Flow Cytometry
· Foods
2023 IN_VITRO
Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism
· Frontiers in Pharmacology
2022 ANIMAL
Co-administering yeast polypeptide and the probiotic, Lacticaseibacillus casei Zhang, significantly improves exercise performance
· Journal of Functional Foods
Browse all 75 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    [Removal of microcystin-LR by lactic acid bacteria].
    · PubMed · 2010
    PMID 20687336 →