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Lacticaseibacillus casei Zhang

◐ Food-origin
Sequenced
Public genome assembly available

Lacticaseibacillus casei Zhang (formerly Lactobacillus casei Zhang), originally isolated from traditional Mongolian fermented dairy, has been studied across a range of animal models examining gut health, immune function, and metabolic parameters. Animal research has examined intestinal mucosal integrity, immune markers in gut-associated lymphoid tissue, and lipid metabolism in hypercholesterolemic models. One in vitro study examined binding of microcystin-LR, a cyanobacterial toxin, though this has not been evaluated in humans. All available strain-specific evidence originates from in vitro and animal studies; human clinical trial data for L. casei Zhang specifically have not been identified in this index. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 33 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+1 more systems

Symptoms in the research

Share of this strain's 7 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+1 more symptoms

Research

75 papers reference this strain in the probiotic database.

Match confidence
2022 ANIMAL
Inhibition of GABAAR or Application of Lactobacillus casei Zhang Alleviates Ulcerative Colitis in Mice: GABAAR as a Potential Target for Intestinal Epithelial Renewal and Repair
· International Journal of Molecular Sciences
2021 ANIMAL
Lactobacillus casei Zhang exerts probiotic effects to antibiotic-treated rats
· Computational and Structural Biotechnology Journal
2021 ANIMAL
FC 083PROBIOTIC L.CASEI ZHANG SLOWS THE PROGRESSION OF ACUTE AND CHRONIC KIDNEY DISEASE
· Nephrology Dialysis Transplantation
2019 ANIMAL
Lactobacillus casei Zhang Prevents Jejunal Epithelial Damage to Early-Weaned Piglets Induced by Escherichia coli K88 via Regulation of Intestinal Mucosal Integrity, Tight Junction Proteins and Immune Factor Expression
· Journal of Microbiology and Biotechnology
2017 IN_VITRO
Protective effect of surface layer proteins isolated from four Lactobacillus strains on hydrogen-peroxide-induced HT-29 cells oxidative stress
· International Journal of Biological Macromolecules
2017 ANIMAL
Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis in mice via adiponectin-elevated different signaling pathways
· Oncotarget
2016 ANIMAL
Protective Effects of Probiotic Lactobacillus casei Zhang on Chronic Alcoholic Liver Disease in Rats and Its Effects on the Expression of Hepatic Cytochrome P450 3A1/2 and Cytochrome c
· Journal of food and nutrition research
2014 IN_VITRO
EFFECTS OF PROBIOTIC Lactobacillus casei Zhang ON THE EXPRESSION OF iNOS/NO IN RAW264.7CELLS AND RELATED MECHANISMS
· Journal of Inner Mongolia Agricultural University
2011 IN_VITRO
Response of Lactobacillus casei to short bile salts exposure revealed by two-dimensional electrophoresis
·
2011 ANIMAL
Lactobacillus casei Zhang stimulates lipid metabolism in hypercholesterolemic rats by affecting gene expression in the liver
· European Journal of Lipid Science and Technology
2010 ANIMAL
Effect of L. casei Zhang PG on the Phagocytic Function of Mouse Macrophages
L. casei Zhang PG对小鼠巨噬细胞吞噬功能的影响
· 青海医学院学报
2010 IN_VITRO
[Removal of microcystin-LR by lactic acid bacteria].
· PubMed
2009 ANIMAL
Influence of Lactobacillus casei Zhang on immunological function of intestinal mucosa associated lymphoid tissues of mice.
· Acta Nutrimenta Sinica
2009 ANIMAL
Effects of L. casei Zhang on ati-oxidative ability in rats.
· Acta Nutrimenta Sinica
2006 ANIMAL
Study on the influence of IgG in serum and SIgA in the gut of mice after oral lactobacillus
· Heilongjiang xumu shouyi
2026 ANIMAL
Lacticaseibacillus casei Zhang modulates iron homeostasis in iron-overloaded mice via an IL-22-dependent pathways
· npj Science of Food
2024 ANIMAL
Integrated oral microgel system ameliorates renal fibrosis by hitchhiking co-delivery and targeted gut flora modulation
· Journal of Nanobiotechnology
2023 IN_VITRO
Rapid Detection of the Activity of Lacticaseibacillus Casei Zhang by Flow Cytometry
· Foods
2023 IN_VITRO
Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism
· Frontiers in Pharmacology
2022 ANIMAL
Co-administering yeast polypeptide and the probiotic, Lacticaseibacillus casei Zhang, significantly improves exercise performance
· Journal of Functional Foods
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Citations

Selected papers that name this strain.

  1. [1]
    [Removal of microcystin-LR by lactic acid bacteria].
    · PubMed · 2010
    PMID 20687336 →