Strain Profile
· NCBI Species Taxon
1582
NCBI Taxonomy's node for this strain's species, not for the strain itself — NCBI has no strain-level node for it. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Lactobacillus casei
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus casei (species-level entry, undesignated strain) is a broadly studied lactic acid bacterium encountered across fermented dairy and non-dairy foods. The indexed research for this species-level entry spans diverse topics, including immune stimulation in animal models, fermentation biochemistry, and food technology applications, without converging on a single well-characterized probiotic strain. Species-level data cannot be reliably attributed to any particular commercial or clinical preparation of L. casei without strain designation, and the indexed studies here do not constitute strain-specific clinical evidence.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 3,881 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 1,368 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Strains of this species
3 strains of Lactobacillus casei in the index, with 731 linked papers between them.
Lactobacillus casei ATCC 334
ATCC
334
Lactobacillus casei ATCC 334 is a well-characterized reference strain widely used in laboratory research to study probiotic biology, fermentation, and food technology.
Precision
Survival
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Food-origin
80 papers
0 comments
Lactobacillus casei Shirota
™ Shirota
Lactobacillus casei Shirota is one of the most extensively studied probiotic strains, with a research history spanning several decades.
Immune
◐
Food-origin
652 papers
0 comments
Lactobacillus casei FG12
DEP
FG12
Lactobacillus casei FG12 is a novel probiotic strain with a single indexed publication, a 2025 rat study examining antioxidant activity and potential effects in a chemically induced cancer model.
Immune
AMR & toxins
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Food-origin
1 papers
0 comments
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
13899 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
OTHER
OTHER
OTHER
2026
OTHER
2026
OTHER
2026
OTHER
2026
ANIMAL
2026
OTHER
2026
ANIMAL
2026
OTHER
2026
OTHER
2026
OTHER
2026
OTHER
2026
IN_VITRO
2026
OTHER
2026
ANIMAL
2026
IN_VITRO
2026
OTHER
2026
OTHER
2026
IN_VITRO
Browse all 13,899 papers →
Molecular cloning and characterisation of alpha subunit of H+-ATPase in Lactobacillus casei Zhang
· RePEc: Research Papers in Economics
Study on the Mechanism of Oxidative Stress Tolerance in Lactic Acid Bacterium Lactobacillus casei IGM394
乳酸菌 Lactobacillus casei IGM394 における酸化ストレス耐性メカニズムに関する研究
· Institutional Repositories DataBase (IRDB)
Expression of E. coli-Derived Fimbrial Adhesin Protein (FimH) Gene in Lactic Acid Bacteria and Functional Analysis of the Fusion Protein
乳酸菌でのE.coli由来の線毛アドヒジュンタンパク質 (FimH) 遺伝子発現と融合タンパク質の機能解析
· Institutional Repositories DataBase (IRDB)
Assessment of Lactic Acid Bacteria Growth Rate, Physicochemical Parameters, Vitamin Contents, and Antioxidant Potentials of Probiotic-Fortified Fruit Juices
· Cureus Journal of Agriculture and Food Science
Correction to “Comparative Analysis of Different Carrier Agents on Functional, Structural, and Thermal Properties of Spray‐Dried Probiotic Lactobacillus casei Powder”
· Cereal Chemistry
EVALUATION OF ANTIBACTERIAL AND ANTIBIOFILM ACTIVITY OF BACTERIOCIN-FUSED ZINC OXIDE NANOPARTICLE AGAINST URINARY TRACT INFECTION PATHOGEN
· Asian Journal of Pharmaceutical and Clinical Research
Development of a recombinant Lactobacillus casei strain expressing Bovine rotavirus VP4 and VP7 proteins as an oral vaccine candidate against calf enteritis.
· PubMed
Engineered Lactobacillus casei targets the IgT-pIgR axis to confer mucosal protection against Aeromonas veronii in snakehead (Channa argus)
· Frontiers in Immunology
Citric Acid–Cross‐Linked Mucoadhesive Pectin Microparticles for Buccal Delivery of Glycyrrhizin and Lactobacillus Casei: Formulation, Characterization, and Evaluation
· ChemistrySelect
Characteristics of antioxidant peptides derived from casein hydrolysis products of Lactobacillus casei 1.0351 and exploration of their pathway of action by molecular docking
· International Dairy Journal
Characteristics of antioxidant peptides derived from casein hydrolysis products of Lactobacillus casei 1.0351 and exploration of their pathway of action by molecular docking
· SSRN Electronic Journal
Biocatalytic bioconversion of whole-plant corn-based total mixed ration with Lactobacillus casei TH14 and molasses improves fermentation efficiency and nutrient utilization
· Biocatalysis and Agricultural Biotechnology
Dynamic modulation of nutritional and flavor profiles in Aronia melanocarpa juice during fermentation with Lactobacillus casei 139
· Food Innovation and Advances
Desarrollo de un producto formulado con quínoa, cebada y Lactobacillus casei ATCC 396 con propiedades funcionales
· FACSALUD-UNEMI
Lactobacillus casei Zhang modulates hippocampal metabolism and cognition in T2DM rats: A microbiota-gut-brain axis study
· The Journal of Nutritional Biochemistry
Application of Synbiotics Lactobacillus Casei and Banana Peel Waste to Improve Growth Performance of African Catfish Clarias Gariepinus in Intensive Aquaculture Systems
· Grouper
Sustainable approach of loading lyophilized (Lactobacillus casei) bacteria into a biopolymer matrix of chitosan for enhanced methyl violet dye removal: characterization, optimization modeling and biosorption mechanism
· Biomass Conversion and Biorefinery
Karakterisasi Fisikokimia dan Viabilitas Lactobacillus Casei pada Es Krim Probiotik dengan Substitusi Tepung Kulit Pisang Kepok
· Karimah Tauhid.
Lactobacillus casei serves as a primary functional strain in fecal microbiota-mediated neuroprotection against cerebral ischemia/reperfusion injury
· Pathology - Research and Practice
The Influence of Lactobacillus casei FA23 as Probiotic and Feed Additive on Enhancing Growth, Health, Gut Integrity, Cecal Microbiota, and Meat Quality in Japanese Quails
· Pakistan Veterinary Journal
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 41910295 →A randomized controlled trial of probiotics to reduce the severity of oral mucositis in patients with oropharyngeal carcinoma undergoing concurrent chemoradiotherapy· Journal of Cancer Research and Therapeutics · 2026
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[2]
Source →Lactobacillus casei Shirota intervention modulates the esophageal microbiome composition in Barrett’s esophagus· medRxiv · 2025
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[3]
Source →The Effects of Probiotic Supplementation on Treatment Outcomes of Patients with Active Tuberculosis: A Systematic Review of Randomized Controlled Trials· Journal Of The Indonesian Medical Association · 2025
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[4]
PMID 39952876 →Nonintravesical Interventions for Preventing Intravesical Recurrence in Patients With Nonmuscle-Invasive Bladder Cancer: A Systematic Review and Meta-Analysis· Clinical Genitourinary Cancer · 2025
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[5]
PMID 40877060 →Enhanced sleep quality and reduced indoxyl sulfate levels following probiotic supplementation were linked to gut microbiota modulation in hemodialysis patients· Journal of the Formosan Medical Association · 2025
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[6]
PMID 41221154 →Lactobacillus casei ’s Antitumor Potential in Colorectal Cancer: Exploring Mechanisms—A Systematic Review· BioMed Research International · 2025
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[7]
PMID 39858898 →Probiotics in the Management of Chronic Bacterial Prostatitis Patients: A Randomized, Double-Blind Trial to Evaluate a Possible Link Between Gut Microbiota Restoring and Symptom Relief· Microorganisms · 2025
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[8]
PMID 39064686 →The Effect of Probiotics on the Management of Pain and Inflammation in Osteoarthritis: A Systematic Review and Meta-Analysis of Clinical Studies· Nutrients · 2024
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[9]
PMID 38788020 →Probiotics combined with atorvastatin administration in the treatment of hyperlipidemia: A randomized, double-blind, placebo-controlled clinical trial· Medicine · 2024
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[10]
PMID 38519563 →Lactobacillus casei Shirota probiotic drinks reduce antibiotic associated diarrhoea in patients with spinal cord injuries who regularly consume proton pump inhibitors: a subgroup analysis of the ECLISP multicentre RCT· Spinal Cord · 2024