Strain Profile
· NCBI Strain Taxon
742815
NCBI Taxonomy's node for this specific strain. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Lacticaseibacillus casei DN-114001
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
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Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
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Public genome assembly available
Lacticaseibacillus casei DN-114001 is a lactic acid bacterium studied in human and animal models in relation to immunomodulation. Research has examined the strain in relation to intestinal immunity and systemic inflammatory markers, with randomized controlled trials examining associations with infections and intestinal health. In vitro studies have examined mechanisms related to immune cell signaling, though clinical efficacy for most purported applications requires additional investigation. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 20 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 13 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+2 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
27 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2021
ANIMAL
2018
ANIMAL
2015
IN_VITRO
2014
RCT
2014
META_ANALYSIS
2014
RCT
2012
OBSERVATIONAL
2012
IN_VITRO
2011
OBSERVATIONAL
2008
ANIMAL
2006
RCT
2006
RCT
2005
RCT
2004
RCT
2004
RCT
2003
OBSERVATIONAL
2002
IN_VITRO
1998
ANIMAL
2024
IN_VITRO
2024
IN_VITRO
Browse all 27 papers →
The Effect of Lactobacillus casei on Experimental Porcine Inflammatory Bowel Disease Induced by Dextran Sodium Sulphate
· Acta Medica (Hradec Kralove Czech Republic)
Dietary Supplementation with Fermented Milk Containing Probiotics Improves Behaviour and Immune Response of Aged Mice
· Journal of Probiotics & Health
Protective activity of probiotic bacteria against 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine (PhIP) – an in vitro study
· Food Additives & Contaminants Part A
Commercially available probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea
· 世界胃肠病学杂志：英文版（电子版）
The Effect of Probiotics Supplementation on Helicobacter pylori Eradication Rates and Side Effects during Eradication Therapy: A Meta-Analysis
· PLoS ONE
Commercially available probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea
· World Journal of Gastroenterology
Efecto de la interrupción en el consumo de leche conteniendo L. casei sobre el sistema inmune
· Redalyc (Universidad Autónoma del Estado de México)
Stimulation of nitric oxide, cytokine and prostaglandin production by low-molecular weight fractions of probiotic Lactobacillus casei lysate.
· PubMed
Changes in Gut Microbiota in Children with Atopic Dermatitis Administered the Bacteria Lactobacillus casei DN – 114001
· Polish Journal of Microbiology
Effect of the administration of a fermented milk containing Lactobacillus casei DN-114001 on intestinal microbiota and gut associated immune cells of nursing mice and after weaning until immune maturity
· BMC Immunology
[Effect of Lactobacillus casei on the incidence of infectious conditions in children].
· PubMed
Efecto de Lactobacillus casei sobre la incidencia de procesos infecciosos en niños/as Effect of lactobacillus casei on the incidence of infectious conditions in children
· DOAJ (DOAJ: Directory of Open Access Journals)
Use of probiotic products in the treatment of intestinal infections in children
Использование пробиотических продуктов в лечении кишечных инфекций у детей
· CyberLeninK (CyberLeninka)
P0900 SUPPLEMENTS OF ONE WEEK TRIPLE DRUG THERAPY WITH SPECIAL PROBIOTIC LACTOBACILLUS CASEI IMUNITASS (STRAIN DN‐114 000) AND STREPTOCOCCUS THERMOPHILUS AND LACTOBACILLUS BULGARICUS IN THE ERADICATION OF H.PYLORI‐COLONIZED CHILDREN: A PROSPECTIVE RANDOMISED TR
· Journal of Pediatric Gastroenterology and Nutrition
P0900 SUPPLEMENTS OF ONE WEEK TRIPLE DRUG THERAPY WITH SPECIAL PROBIOTIC LACTOBACILLUS CASEI IMUNITASS (STRAIN DN-114 000) AND STREPTOCOCCUS THERMOPHILUS AND LACTOBACILLUS BULGARICUS IN THE ERADICATION OF H.PYLORI-COLONIZED CHILDREN: A PROSPECTIVE RANDOMISED TR
· Journal of Pediatric Gastroenterology and Nutrition
Effect of fermented milk containing the probiotic Lactobacillus casei DN-114001 on winter infections in free-living elderly subjects: a randomised, controlled pilot study.
· PubMed
Increased mucosal tumour necrosis factor α production in Crohn’s disease can be downregulated ex vivo by probiotic bacteria
· Gut
Effet bénéfique d'un lait fermenté par Lactobacillus casei (DN 114001) sur la diarrhee à rotavirus : étude chez un nouveau modèle de raton sans germe
· HAL (Le Centre pour la Communication Scientifique Directe)
Probiotic-Enriched Ice Cream with Fermented White Kidney Bean Homogenate: Survival, Antioxidant Activity, and Potential Health Benefits
· Preprints.org
Probiotic-Enriched Ice Cream with Fermented White Kidney Bean Homogenate: Survival, Antioxidant Activity, and Potential for Future Health Benefits
· Molecules
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Citations
Selected papers that name this strain.
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[1]
PMID 25400470 →Commercially available probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea· World Journal of Gastroenterology · 2014
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[2]
PMID 25365320 →The Effect of Probiotics Supplementation on Helicobacter pylori Eradication Rates and Side Effects during Eradication Therapy: A Meta-Analysis· PLoS ONE · 2014
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[3]
PMID 16913215 →[Effect of Lactobacillus casei on the incidence of infectious conditions in children].· PubMed · 2006
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[4]
Source →Efecto de Lactobacillus casei sobre la incidencia de procesos infecciosos en niños/as Effect of lactobacillus casei on the incidence of infectious conditions in children· DOAJ (DOAJ: Directory of Open Access Journals) · 2006
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[5]
Source →P0900 SUPPLEMENTS OF ONE WEEK TRIPLE DRUG THERAPY WITH SPECIAL PROBIOTIC LACTOBACILLUS CASEI IMUNITASS (STRAIN DN‐114 000) AND STREPTOCOCCUS THERMOPHILUS AND LACTOBACILLUS BULGARICUS IN THE ERADICATION OF H.PYLORI‐COLONIZED CHILDREN: A PROSPECTIVE RANDOMISED TR· Journal of Pediatric Gastroenterology and Nutrition · 2004
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[6]
PMID 12679825 →Effect of fermented milk containing the probiotic Lactobacillus casei DN-114001 on winter infections in free-living elderly subjects: a randomised, controlled pilot study.· PubMed · 2003