Strain Profile
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Lactobacillus crispatus M247
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus crispatus M247 is a rod-shaped lactic acid bacterium characterized by its mucus-binding properties and production of antimicrobial compounds. Animal and human studies have examined this strain in the context of vaginal and urinary health, including mechanisms such as competitive exclusion and metabolite production. Recent in vitro research has examined the strain's bioactive metabolites, and human observational studies have examined associations with health outcomes in this area. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 22 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 4 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
27 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
OTHER
2025
RCT
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
OBSERVATIONAL
2024
OBSERVATIONAL
2023
WGS
2023
OBSERVATIONAL
2023
OBSERVATIONAL
2022
RCT
2022
RCT
2022
REVIEW
2021
OBSERVATIONAL
2019
IN_VITRO
Browse all 27 papers →
Clinical and vaginal microbiota effects of oral Lactobacillus crispatus M247 combined with vaginal laser therapy in menopausal women with atrophic vulvovaginitis: a prospective, randomized and controlled study
· Lasers in Medical Science
Effect of orally administered L. crispatus M247 in favoring HR-HPV clearance and CST shift: results from a randomized, multi-center, placebo-controlled trial
· Scientific Reports
The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections
· Frontiers in Cellular and Infection Microbiology
Image 3_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png
· Figshare
Table 3_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.xlsx
· Figshare
Image 2_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png
· Figshare
Table 2_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.xlsx
· Figshare
Image 1_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png
· Figshare
Table 4_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.xlsx
· Figshare
Table 1_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.docx
· Figshare
O-302 Impact of personalized nutrition and Lactobacillus crispatus-M247 administration on euploid blastocyst transfer outcomes in patients with unhealthy lifestyles: A matched case-control study
· Human Reproduction
A prospective observational study to evaluate impact of oral supplementation with AHCC and Lactobacillus Crispatus M247 on HPV clearance and low-grade squamous intraepithelial lesion regression
· Annals of Research in Oncology
The mobilome of Lactobacillus crispatus M247 includes two novel genetic elements: Tn7088 coding for a putative bacteriocin and the siphovirus prophage ΦM247
· Microbial Genomics
Effect of L. crispatus M247 Administration on Pregnancy Outcomes in Women Undergoing IVF: A Controlled, Retrospective, Observational, and Open-Label Study
· Microorganisms
Effect of L. crispatus M247 Administration on Pregnancy Out-comes in Women Undergoing IVF: a Controlled, Retrospective, Observational and Open-label Study
· Preprints.org
Lactobacillus crispatus M247 oral administration: Is it really an effective strategy in the management of papillomavirus-infected women?
· Infectious Agents and Cancer
The Lactobacillus Crispatus M247 oral administration: it really is an effective strategy in the management of papillomavirus-infected women?
· Research Square
Lactobacillus crispatus M247: Characteristics of a Precision Probiotic Instrument for Gynecological and Urinary Well-Being
· Microbiology Research
Oral administration of Lactobacillus crispatus M247 to papillomavirus-infected women: results of a preliminary, uncontrolled, open trial
· Minerva Obstetrics and Gynecology
Antibiotic resistance profile and adhesion properties of Lactobacillus crispatus M247
· Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods
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Citations
Selected papers that name this strain.
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[1]
PMID 41125728 →Effect of orally administered L. crispatus M247 in favoring HR-HPV clearance and CST shift: results from a randomized, multi-center, placebo-controlled trial· Scientific Reports · 2025
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[2]
Source →The Lactobacillus Crispatus M247 oral administration: it really is an effective strategy in the management of papillomavirus-infected women?· Research Square · 2022
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[3]
PMID 17634514 →Aggregating Phenotype in Lactobacillus crispatus Determines Intestinal Colonization and TLR2 and TLR4 Modulation in Murine Colonic Mucosa· Clinical and Vaccine Immunology · 2007
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[4]
PMID 15681150 →Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice· FEMS Immunology & Medical Microbiology · 2004