Strain Profile
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Limosilactobacillus reuteri RC-14
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Limosilactobacillus reuteri RC-14 has been studied primarily in the context of urogenital and oral health, often in combination with its companion strain L. rhamnosus GR-1. Randomized controlled trials have examined oral supplementation in relation to vaginal flora and bacterial vaginosis outcomes across different populations, including a Chinese cohort study. Additional randomized controlled trials have explored the strain in children's dental health and as an adjunct in upper respiratory tract infection studies, and in vitro research has examined antimicrobial and anti-Candida activity. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 117 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+4 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 83 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
141 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
REVIEW
2025
IN_VITRO
2025
REVIEW
2025
RCT
2025
RCT
2025
REVIEW
2024
OBSERVATIONAL
2023
RCT
2022
RCT
2022
OBSERVATIONAL
2022
IN_VITRO
2021
RCT
2021
IN_VITRO
2021
RCT
2021
RCT
2021
RCT
2021
RCT
2021
RCT
2021
RCT
2021
RCT
Browse all 141 papers →
Uso de Probióticos como estratégia nutricional adjuvante no manejo da candidíase vulvovaginal recorrente
· Brazilian Journal of Implantology and Health Sciences
Limosilactobacillus reuteri ‐ Fusobacterium nucleatum Interactions Modulate Biofilm Composition and Immunogenicity
· Journal of Periodontal Research
USO DE PROBIÓTICOS COMO TERAPIA COMPLEMENTAR A CANDIDÍASE DE REPETIÇÃO
· Revista Ibero-Americana de Humanidades, Ciências e Educação
Changes in the Genital Microbiome and Inflammation Among Women Using 30-Day L. Rhamnosus/L. Reuteri Probiotic in Combination with Intravaginal Estradiol: Findings from a Pilot, Open-Label, Phase I Clinical Trial
· medRxiv
The Role of probiotic supplementation in reducing antibiotic-associated vaginal dysbiosis in women undergoing antibiotic treatment for urinary tract infections (Utis) at Wasit city
· International Journal of Medicine Sciences
Exploring Probiotics as an Effective Treatment for Vaginitis: A Systematic Review
· International journal of basic science in medicine
Effects of Lactobacillus reuteri Intake on the Periodontal Pathogens
· International Journal of Clinical Preventive Dentistry
A placebo‐controlled randomized clinical trial of antibiotics versus probiotics as an adjuvant to nonsurgical periodontal treatment among smokers with Stage III, Grade C generalized periodontitis
· Clinical Advances in Periodontics
Prevention of Recurrent Childhood Caries with Probiotic Supplements: A Randomized Controlled Trial with a 12-Month Follow-Up
· Probiotics and Antimicrobial Proteins
Comparison of a novel treatment protocol with oral fluconazole vs probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 in the treatment of recurrent vulvovaginal candidiasis
· Italian Journal of Gynaecology and Obstetrics
Glycerol strengthens probiotic effect of Limosilactobacillus reuteri in oral biofilms: A synergistic synbiotic approach
· Molecular Oral Microbiology
Effect of drops containing Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) on plaque acidogenicity and other caries-related variables in orthodontic patients
· BMC Microbiology
The Effect of Parabiotic Reuterin on the Expression of Genes Involved in Candida albicans Biofilm Formation: An Ex vivo Study
· Journal of Dentistry Indonesia
The use of Lactobacillus reuteri DSM 17938 and ATCC PTA 5289 on oral health indexes in a school population: A pilot randomized clinical trial
· International Journal of Immunopathology and Pharmacology
Modern approaches to the treatment of bacterial vaginosis and vulvovaginal candidiasis
· Russian Bulletin of Obstetrician-Gynecologist
Učinak probiotika Lactobacillus reuteri kao dodatne terapije uz nekirurško liječenje na halitozu u bolesnika s parodontitisom: randomizirano placebom kontrolirano ispitivanje
· Repository of the School of Dental Medicine University of Zagreb
Vaginal & gut microbiota diversity in pregnant women with bacterial vaginosis & effect of oral probiotics
· The Indian Journal of Medical Research
Limosilactobacillus reuteri ATCC PTA 5289 and DSM 17938 as adjuvants to improve evolution of pharyngitis/tonsillitis in children: randomised controlled trial
· Beneficial Microbes
Probiotic Lacticaseibacillus rhamnosus GR-1 and Limosilactobacillus reuteri RC-14 as an Adjunctive Treatment for Bacterial Vaginosis Do Not Increase the Cure Rate in a Chinese Cohort: A Prospective, Parallel‐Group, Randomized, Controlled Study
· Frontiers in Cellular and Infection Microbiology
Effect of probiotic Lactobacillus reuteri as an adjunct to nonsurgical treatment on halitosis of patients with periodontitis: a randomised placebo - controlled trial
·
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Citations
Selected papers that name this strain.
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[1]
Source →Uso de Probióticos como estratégia nutricional adjuvante no manejo da candidíase vulvovaginal recorrente· Brazilian Journal of Implantology and Health Sciences · 2026
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[2]
Source →Exploring Probiotics as an Effective Treatment for Vaginitis: A Systematic Review· International journal of basic science in medicine · 2025
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[3]
Source →Changes in the Genital Microbiome and Inflammation Among Women Using 30-Day L. Rhamnosus/L. Reuteri Probiotic in Combination with Intravaginal Estradiol: Findings from a Pilot, Open-Label, Phase I Clinical Trial· medRxiv · 2025
-
[4]
Source →The Role of probiotic supplementation in reducing antibiotic-associated vaginal dysbiosis in women undergoing antibiotic treatment for urinary tract infections (Utis) at Wasit city· International Journal of Medicine Sciences · 2025
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[5]
Source →USO DE PROBIÓTICOS COMO TERAPIA COMPLEMENTAR A CANDIDÍASE DE REPETIÇÃO· Revista Ibero-Americana de Humanidades, Ciências e Educação · 2025
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[6]
PMID 34295831 →Probiotic Lacticaseibacillus rhamnosus GR-1 and Limosilactobacillus reuteri RC-14 as an Adjunctive Treatment for Bacterial Vaginosis Do Not Increase the Cure Rate in a Chinese Cohort: A Prospective, Parallel‐Group, Randomized, Controlled Study· Frontiers in Cellular and Infection Microbiology · 2021
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[7]
PMID 33789556 →Limosilactobacillus reuteri ATCC PTA 5289 and DSM 17938 as adjuvants to improve evolution of pharyngitis/tonsillitis in children: randomised controlled trial· Beneficial Microbes · 2021
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[8]
PMID 32019222 →Effect of Oral Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on the Vaginal Microbiota, Cytokines and Chemokines in Pregnant Women· Nutrients · 2020
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[9]
PMID 32325794 →A Randomized Controlled Open Label Crossover Trial to Study Vaginal Colonization of Orally Administered Lactobacillus Reuteri RC-14 and Rhamnosus GR-1 in Pregnant Women at High Risk for Preterm Labor· Nutrients · 2020
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[10]
PMID 31520543 →A dual‐strain Lactobacilli reuteri probiotic improves the treatment of residual pockets: A randomized controlled clinical trial· Journal Of Clinical Periodontology · 2019