Strain Profile
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Lactobacillus gasseri SBT2055
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus gasseri SBT2055 (now reclassified as Lactobacillus paragasseri SBT2055) has been studied in human observational and randomized controlled trials. Two placebo-controlled RCTs examined this strain in relation to immune responses — specifically activation of plasmacytoid dendritic cells, immune cells that produce antiviral proteins — and subjective cold symptoms in healthy adults. In vitro studies have examined its adherence to intestinal surfaces and interactions with pathogens such as Campylobacter jejuni, while animal model research has explored its potential role in the context of Helicobacter suis colonization. The evidence base includes human trial data, and additional independent replication would be needed to strengthen confidence in these findings. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 25 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+1 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 21 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+1 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
48 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
RCT
2025
REVIEW
2025
IN_VITRO
2025
REVIEW
2025
ANIMAL
2025
REVIEW
2023
RCT
2017
ANIMAL
2016
IN_VITRO
2015
ANIMAL
2014
IN_VITRO
2013
RCT
2012
ANIMAL
2006
OBSERVATIONAL
2001
OBSERVATIONAL
2025
ANIMAL
2022
RCT
2019
ANIMAL
2019
ANIMAL
2017
ANIMAL
Browse all 48 papers →
Correlation between plasmacytoid dendritic cell activation and suppression of subjective physical symptoms following Lactobacillus paragasseri SBT2055 ingestion: a randomized, double-blind, placebo-controlled, parallel-group comparative study
· Frontiers in Nutrition
The Role of Probiotics in Modulating Gut Microbiota and Metabolic Health for Weight Management: A Mini Review
· Acta Microbiologica Hellenica
DNA from Lactobacillus paragasseri SBT2055 Activates Plasmacytoid Dendritic Cells and Induces IFN-α via TLR9
· Microorganisms
The Role of Probiotics and Gut Microbiota in Nutrient Metabolism
· Microbial Science Archives
Lactobacillus paragasseri SBT2055 suppressed insulin resistance and fatty liver by inhibiting oxidative stress and inflammation in high-fat diet-induced obese mice
· Beneficial Microbes
(untitled)
· Microbial Science Archives
Lactobacillus paragasseri SBT2055 Activates Plasmacytoid Dendritic Cells and Improves Subjective Symptoms of Common Cold in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Parallel-Group Comparative Trial
· Nutrients
Protective effects of lactic acid bacteria on influenza A virus infection
· AIMS Allergy and Immunology
In vitro investigation of molecules involved in Lactobacillus gasseri SBT2055 adhesion to host intestinal tract components
· Journal of Applied Microbiology
Mouse Models for Assessing the Protective Efficacy of Lactobacillus gasseri SBT2055 against Helicobacter suis Infection Associated with the Development of Gastric Mucosa‐Associated Lymphoid Tissue Lymphoma
· Helicobacter
Lactobacillus gasseri SBT2055 Reduces Infection by and Colonization of Campylobacter jejuni
· PLoS ONE
Safety of Excessive Intake of Fermented Milk Containing Probiotic Lactobacillus gasseri SBT2055
プロバイオティクス Lactobacillus gasseri SBT2055 を含有する発酵乳の過剰摂取時の安全性
· 薬理と治療
Prevention of Rotavirus‐induced Diarrhea
· Journal of Pediatric Gastroenterology and Nutrition
Monitoring and Survival of Lactobacillus gasseri SBT2055 in the Human Intestinal Tract
· Microbiology and Immunology
Establishment of orally-administered Lactobacillus gasseri SBT2055SR in the gastrointestinal tract of humans and its influence on intestinal microflora and metabolism
· Journal of Applied Microbiology
The Therapeutic Effect and Mechanism of Lactobacillus gardneri on Nonalcoholic Fatty Liver Disease
· Journal of Microbiology and Biotechnology
Intake of Lactobacillus paragasseri SBT2055 improves subjective symptoms of common cold during winter season in healthy adults: A randomized, double-blind, placebo-controlled parallel-group comparative study
· Frontiers in Nutrition
Prevention of respiratory syncytial virus infection with probiotic lactic acid bacterium Lactobacillus gasseri SBT2055
· Scientific Reports
Lactobacillus gasseri SBT2055 Enhances Oral Tolerance in Mice via Breastfeeding
· Nippon Eiyo Shokuryo Gakkaishi
Oral administration of Lactobacillus gasseri SBT2055 is effective in preventing Porphyromonas gingivalis-accelerated periodontal disease
· Scientific Reports
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 40716757 →Lactobacillus paragasseri SBT2055 suppressed insulin resistance and fatty liver by inhibiting oxidative stress and inflammation in high-fat diet-induced obese mice· Beneficial Microbes · 2025
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[2]
PMID 37892533 →Lactobacillus paragasseri SBT2055 Activates Plasmacytoid Dendritic Cells and Improves Subjective Symptoms of Common Cold in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Parallel-Group Comparative Trial· Nutrients · 2023
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[3]
Source →Therapeutic and preventive potential of probiotics against COVID-19· · 2020
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[4]
PMID 26999673 →In vitro investigation of molecules involved in Lactobacillus gasseri SBT2055 adhesion to host intestinal tract components· Journal of Applied Microbiology · 2016
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[5]
PMID 25627811 →Mouse Models for Assessing the Protective Efficacy of Lactobacillus gasseri SBT2055 against Helicobacter suis Infection Associated with the Development of Gastric Mucosa‐Associated Lymphoid Tissue Lymphoma· Helicobacter · 2015
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[6]
PMID 25264604 →Lactobacillus gasseri SBT2055 Reduces Infection by and Colonization of Campylobacter jejuni· PLoS ONE · 2014
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[7]
PMID 23614897 →Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial· British Journal Of Nutrition · 2013
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[8]
PMID 22395191 →Prevention of Rotavirus‐induced Diarrhea· Journal of Pediatric Gastroenterology and Nutrition · 2012
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[9]
PMID 11298228 →Establishment of orally-administered Lactobacillus gasseri SBT2055SR in the gastrointestinal tract of humans and its influence on intestinal microflora and metabolism· Journal of Applied Microbiology · 2001