Strain Profile
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Bifidobacterium bifidum MIMBb75
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Bifidobacterium bifidum MIMBb75 has been the subject of two randomized controlled trials in the context of irritable bowel syndrome (IBS), a functional gut disorder characterized by abdominal discomfort and altered bowel habits, including a 2011 trial and a 2021 trial of a heat-inactivated formulation. Complementary in vitro and animal studies have examined how this strain interacts with intestinal epithelial cells, immune signaling, and colonization resistance against pathogens. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 22 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 10 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
24 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
IN_VITRO
2023
REVIEW
2021
RCT
2019
ANIMAL
2019
ANIMAL
2018
ANIMAL
2016
IN_VITRO
2016
IN_VITRO
2014
IN_VITRO
2013
ANIMAL
2012
ANIMAL
2012
IN_VITRO
2012
IN_VITRO
2011
RCT
2011
OTHER
2023
REVIEW
2015
ANIMAL
2015
ANIMAL
2014
META_ANALYSIS
2014
IN_VITRO
Browse all 24 papers →
Viable and Heat-Inactivated Bifidobacterium bifidum MIMBb75 Protect the Intestinal Barrier
· Microorganisms
Are postbiotics key to the potential benefits of fermented foods?
· The Lancet. Gastroenterology & hepatology
Hitzeinaktivierter Bifidobacterium-bifidum-Stamm mildert Reizdarmsyndrom
· Aktuelle Ernährungsmedizin
Effect of bifidobacteria on intestinal injury and flora in a mouse model of ulcerative colitis
· Tropical Journal of Pharmaceutical Research
Effects of Bifidobacterium bifidum in Mice Infected with Citrobacter rodentium
· Microorganisms
A282 EFFECTS OF BIFIDOBACTERIUM BIFIDUM IN MICE INFECTED WITH CITROBACTER RODENTIUM.
· Journal of the Canadian Association of Gastroenterology
Expression of MicroRNA‐148a and its Target Gene EPAS1 (Endothelial PAS domain‐containing protein 1) in Intestinal Cells in Response to Bifidobacterium bifidum MIMBb75
· The FASEB Journal
Time‐ and strain‐specific downregulation of intestinal EPAS1 via miR‐148a by Bifidobacterium bifidum
· Molecular Nutrition & Food Research
Murein Lytic Enzyme TgaA of Bifidobacterium bifidum MIMBb75 Modulates Dendritic Cell Maturation through Its Cysteine- and Histidine-Dependent Amidohydrolase/Peptidase (CHAP) Amidase Domain
· Applied and Environmental Microbiology
Impact of Bifidobacterium bifidum MIMBb75 on mouse intestinal microorganisms
· FEMS Microbiology Ecology
The Impact of Bifidobacterium bifidum and its Surface Protein BopA on the Murine Intestinal Barrier and Endogenous Microbiota Composition
· TSpace (University of Toronto)
Improved adhesive properties of recombinant bifidobacteria expressing the Bifidobacterium bifidum-specific lipoprotein BopA
· Microbial Cell Factories
Characterization of bifidobacterial adhesion to intestinal epithelial cells
· OPen Access Repositorium der Universität Ulm (OPARU) (Ulm University)
Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life -- a double-blind, placebo-controlled study
· Alimentary Pharmacology & Therapeutics
Bifidobacterium bifidum MIMBb75 in irritable bowel syndrome: authors’ reply
· Alimentary Pharmacology & Therapeutics
Non-prescription Therapeutics
· The American Journal of Gastroenterology
Intestinal microRNA Response to Citrobacter rodentium in the Presence and Absence of Bifidobacterium bifidum MIMBb75
· TSpace (University of Toronto)
Development and Application of a Novel Real‐Time PCR Assay for Citrobacter rodentium Quantification
· The FASEB Journal
Síndrome del intestino irritable: papel del sistema inmune y de los probióticos
· Dialnet (Universidad de la Rioja)
TgaA, a VirB1-Like Component Belonging to a Putative Type IV Secretion System of Bifidobacterium bifidum MIMBb75
· Applied and Environmental Microbiology
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Citations
Selected papers that name this strain.
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[1]
PMID 42354973 →Viable and Heat-Inactivated Bifidobacterium bifidum MIMBb75 Protect the Intestinal Barrier· Microorganisms · 2026
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[2]
PMID 27883285 →Time‐ and strain‐specific downregulation of intestinal EPAS1 via miR‐148a by Bifidobacterium bifidum· Molecular Nutrition & Food Research · 2016
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[3]
PMID 24814791 →Murein Lytic Enzyme TgaA of Bifidobacterium bifidum MIMBb75 Modulates Dendritic Cell Maturation through Its Cysteine- and Histidine-Dependent Amidohydrolase/Peptidase (CHAP) Amidase Domain· Applied and Environmental Microbiology · 2014
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[4]
PMID 22694891 →Improved adhesive properties of recombinant bifidobacteria expressing the Bifidobacterium bifidum-specific lipoprotein BopA· Microbial Cell Factories · 2012
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[5]
PMID 21418261 →Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life -- a double-blind, placebo-controlled study· Alimentary Pharmacology & Therapeutics · 2011