Strain Profile
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Bifidobacterium longum 1714
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Bifidobacterium longum 1714 is among the strains studied under the term "psychobiotic," used for gut bacteria examined for potential effects via the gut-brain axis. Multiple randomized controlled trials in healthy adults have examined this strain in relation to stress-related electrophysiology, social cognition, sleep quality, well-being, and mood, including a 2026 placebo-controlled trial. In vitro work has examined exopolysaccharides and tryptophan metabolism in relation to immune signaling, though the mechanisms relevant to humans remain under investigation. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 16 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 12 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
20 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
REVIEW
2026
IN_VITRO
2026
RCT
2025
RCT
2025
IN_VITRO
2025
RCT
2024
RCT
2020
RCT
2019
REVIEW
2019
RCT
2019
RCT
2016
RCT
2014
ANIMAL
2025
RCT
2023
RCT
2021
OBSERVATIONAL
2019
OTHER
2017
OTHER
2025
REVIEW
2025
REVIEW
Browse all 20 papers →
The Combination of Anxiety and Depressive Disorders in Patients with Irritable Bowel Syndrome (Literature Review and Expert Council Resolution)
· Russian Journal of Gastroenterology Hepatology Coloproctology
Integrating microbial genomics and neurotranscriptomics to understand the impact of probiotic strains on neurological health
· Frontiers in Cellular and Infection Microbiology
Effects of Bifidobacterium longum 1714 on low mood and related symptoms: A randomized, double-blind, placebo-controlled trial.
· Experimental and Clinical Psychopharmacology
P0583 The Effects of a Dual-Strain Probiotic Versus Placebo on Cytokine Levels in Patients with Ulcerative Colitis
· Journal of Crohn s and Colitis
Complementary immunoregulatory effects of Bifidobacterium longum 1714TM associated exopolysaccharide and tryptophan metabolism
· Current Research in Microbial Sciences
P0648 The Safety and Effects of a Dual-Strain Probiotic Versus Placebo on Fatigue in Patients with Ulcerative Colitis
· Journal of Crohn s and Colitis
Bifidobacterium longum 1714 improves sleep quality and aspects of well-being in healthy adults: a randomized, double-blind, placebo-controlled clinical trial
· Scientific Reports
Improvements in sleep indices during exam stress due to consumption of a Bifidobacterium longum
· Brain Behavior & Immunity - Health
Psychobiotics: Shaping the Mind With Gut Bacteria
· The American Journal of Gastroenterology
Bifidobacterium longum 1714™ Strain Modulates Brain Activity of Healthy Volunteers During Social Stress
· The American Journal of Gastroenterology
Bifidobacterium longum 1714 Does Not Modulate Reactivity to Social Stress
· The American Journal of Gastroenterology
Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers
· Translational Psychiatry
Bifidobacteria exert strain‐specific effects on stress‐related behavior and physiology in BALB/c mice
· Neurogastroenterology & Motility
P1004 The Effects of a Dual-Strain Probiotic Versus Placebo on the Microbiome in Patients with Ulcerative Colitis
· Journal of Crohn s and Colitis
Impact of Bifidobacterium longum1714® on maternal cytokine response in peripheral blood mononuclear cells
· Cytokine
Microbiota in development and stress management
· Arrow@dit (Dublin Institute of Technology)
Eppur Si Muove: The Cyberball Game Is a Stress Model, and Bifidobacterium longum 1714™ Helps Coping With It
· The American Journal of Gastroenterology
Kaleidoscope
· The British Journal of Psychiatry
Systematic analysis of the pharmacology of saffron extracts in the context of complex pharmacotherapy for depression
· Neurology neuropsychiatry Psychosomatics
The psychobiotic revolution: comprehending the optimistic role of gut microbiota on gut-brain axis during neurological and Gastrointestinal (GI) disorders
· World Journal of Microbiology and Biotechnology
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →The Combination of Anxiety and Depressive Disorders in Patients with Irritable Bowel Syndrome (Literature Review and Expert Council Resolution)· Russian Journal of Gastroenterology Hepatology Coloproctology · 2026
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[2]
PMID 41140527 →Complementary immunoregulatory effects of Bifidobacterium longum 1714TM associated exopolysaccharide and tryptophan metabolism· Current Research in Microbial Sciences · 2025
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[3]
PMID 38355674 →Bifidobacterium longum 1714 improves sleep quality and aspects of well-being in healthy adults: a randomized, double-blind, placebo-controlled clinical trial· Scientific Reports · 2024
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[4]
PMID 30998517 →Bifidobacterium longum 1714™ Strain Modulates Brain Activity of Healthy Volunteers During Social Stress· The American Journal of Gastroenterology · 2019
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[5]
PMID 31268916 →Psychobiotics: Shaping the Mind With Gut Bacteria· The American Journal of Gastroenterology · 2019
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[6]
PMID 27801892 →Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers· Translational Psychiatry · 2016