Bifidobacterium longum
Bifidobacterium longum is a well-characterized commensal species found throughout the human gut, with a particularly studied role in early-life microbiome establishment. The available evidence base for this strain is early-stage and varied: in vitro studies have explored enzyme activity, sulfur metabolism, and colon cancer cell lines, while animal model research has examined gut barrier function and inflammatory cytokines in colitis contexts. One observational study examines how diet and milk glycans influence B. longum subspecies dynamics in the infant gut microbiome. No human clinical trials appear in this strain's evidence set. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 2,472 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 827 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Strains of this species
17 strains of Bifidobacterium longum in the index, with 438 linked papers between them.
Bifidobacterium longum NCC2705
Bifidobacterium longum NCC2705 is a well-characterized probiotic strain whose complete genome has been sequenced and studied extensively, providing a detailed picture of how it colonizes and persists in the gut.
Bifidobacterium longum 1714
Bifidobacterium longum 1714 is among the strains studied under the term "psychobiotic," used for gut bacteria examined for potential effects via the gut-brain axis.
Bifidobacterium longum BB536
Bifidobacterium longum strain BB536 is a gram-positive anaerobic bacterium native to the human gastrointestinal tract.
Bifidobacterium longum R0175
Bifidobacterium longum R0175 is most commonly studied as part of a combination formula with Lactobacillus helveticus R0052, and several RCTs using this pair have examined anxiety and psychological well-being in healthy a…
Bifidobacterium longum BL-05
Bifidobacterium longum strain BL-05 is a gram-positive anaerobic bacterium native to the human gastrointestinal tract.
Bifidobacterium longum ES1
Bifidobacterium longum ES1 has been studied in laboratory settings for an anti-inflammatory profile, including in vitro work examining pro-inflammatory signaling associated with certain gut conditions.
Bifidobacterium longum CECT7347
Bifidobacterium longum CECT7347 has been studied in animal models in relation to reproductive health markers, with research in zebrafish examining sperm quality and anxiety-related behavior over repeated spermatogenic cy…
Bifidobacterium longum SP 07/3
Bifidobacterium longum SP 07/3 has been studied primarily as one component of a multi-strain combination, alongside Lactobacillus gasseri PA 16/8 and Bifidobacterium bifidum M 20/5.
Bifidobacterium longum AH1206
Bifidobacterium longum AH1206 has been studied for its ability to establish itself in the human gastrointestinal tract, including a 2016 randomized controlled trial examining colonization and its ecological impact on the…
Bifidobacterium longum W11
Bifidobacterium longum W11 is a strain notable for its rifaximin resistance and has been studied primarily in the context of gastrointestinal health, particularly constipation and irritable bowel syndrome.
Bifidobacterium longum NCC3001
Bifidobacterium longum NCC3001 has one of the more developed gut-brain research profiles among probiotic strains.
Bifidobacterium longum MC42
Bifidobacterium longum MC-42 is a strain of B.
Bifidobacterium longum APC1472
Bifidobacterium longum APC1472 has been studied in the context of obesity and metabolic health, with at least one published randomized controlled trial examining human participants alongside parallel rodent work.
Bifidobacterium longum KACC 91563
Bifidobacterium longum KACC 91563 is an anaerobic bacterium studied for its immunomodulatory and metabolic properties.
Bifidobacterium longum F58-9
Bifidobacterium longum F58-9 is a designated strain of B.
Bifidobacterium longum GA24
Bifidobacterium longum GA24 belongs to a species with a broad probiotic research history, though strain-specific indexed evidence for GA24 is limited.
Bifidobacterium longum FGSZY16M3
Bifidobacterium longum FGSZY16M3 is a strain of the well-established B.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
3793 papers reference this strain in the probiotic database.
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →The impact of probiotics on gut health and immune system modulation: A comprehensive study· Journal of Advances in Microbiology Research · 2026
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[2]
PMID 41799757 →Effect of Bifidobacterium longum on cognition and microbiota in post-stroke patients: a single-blinded, controlled trial· International Journal of Medical Sciences · 2026
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[3]
PMID 42047238 →Effects of Live and Heat‐Treated Bifidobacterium longum CECT 7347 in Adults With Allergic Rhinitis: A Randomised, Double‐Blind, Placebo‐Controlled Trial· Allergy · 2026
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[4]
PMID 41523285 →Probiotic Supplementation With Bifidobacterium longum Subsp. Longum BL21 Improves Glycemic Control and Modulates Gut Microbiota in Type 2 Diabetes: A Randomized Controlled Trial· Food Science & Nutrition · 2026
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[5]
PMID 41682832 →Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome· Journal of Clinical Medicine · 2026
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[6]
Source →Adjunctive Bifidobacterium longum SX-1326 improves the therapeutic efficacy of Acupotomy in post-stroke dysphagia: A randomized, double-blind, placebo-controlled study· Journal of Functional Foods · 2026
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[7]
Source →Targeting the “gut-immune axis”: Bifidobacterium longum subsp. infantis CCFM111 serves as a novel therapeutic for pediatric allergic rhinitis· Food Science and Human Wellness · 2026
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[8]
PMID 39940249 →Bifidobacterium infantis and Bifidobacterium breve Improve Symptomatology and Neuronal Damage in Neurodegenerative Disease: A Systematic Review· Nutrients · 2025
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[9]
PMID 40817120 →Strain specific effects of probiotic supplementation on serum amino acid profiles in Alzheimer’s disease: a randomized, double blind, placebo controlled trial· Scientific Reports · 2025
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[10]
PMID 40442154 →Integrated multi-omics reveals different host crosstalk of atopic dermatitis-enriched Bifidobacterium longum Strains· npj Biofilms and Microbiomes · 2025