Strain Profile
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Bifidobacterium longum W11

◔ Human-origin
Sequenced
Public genome assembly available

Bifidobacterium longum W11 is a strain notable for its rifaximin resistance and has been studied primarily in the context of gastrointestinal health, particularly constipation and irritable bowel syndrome. In vitro research has examined a genetic factor governing the breakdown of arabinan, a plant-derived fiber. Observational clinical work has examined IBS constipation-variant symptoms in the context of administration alongside synbiotic formulations or antibiotics. The evidence base for W11 is largely observational and mechanistic rather than from large randomized trials. Strain-specific data is still maturing; W11 should not be viewed as a treatment for any gastrointestinal disease. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 15 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 10 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

16 papers reference this strain in the probiotic database.

Match confidence
2025 OBSERVATIONAL
Targeted probiotic therapy in irritable bowel syndrome: a clinical evaluation on Clostridium butyricum CBM588 and Bifidobacterium longum W11
· Frontiers in Medicine
2024 REVIEW
A SYSTEMATIC MAPPING REVIEW OF IN-VITRO AND IN-VIVO EVIDENCES EXPLORING THE ROLE OF STRAIN-SPECIFIC PROBIOTIC BIFIDOBACTERIUM LONGUM W11
· International Journal of Pharmaceutical Sciences and Drug Research
2024 IN_VITRO
The Anti-Constipation Effect of Bifidobacterium Longum W11 Is Likely Due to a Key Genetic Factor Governing Arabinan Utilization
· Microorganisms
2020 OBSERVATIONAL
Effects of rifaximin-resistant Bifidobacterium longum W11 in subjects with symptomatic uncomplicated diverticular disease treated with rifaximin
· Minerva Gastroenterologica e Dietologica
2017 IN_VITRO
Immunomodulatory Effects of Bifidobacterium longum W11 Produced Exopolysaccharide on Cytokine Production
· Current Pharmaceutical Biotechnology
2017 WGS
Complete Genome Sequence of Bifidobacterium longum W11 (LMG P-21586), Used as a Probiotic Strain
· Genome Announcements
2017 REVIEW
Bifidobacterium longum W11: an antibiotic-resistant probiotic
· Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods
2016 IN_VITRO
The Possible Innovative Use of Bifidobacterium longum W11 in Association With Rifaximin
· Journal of Clinical Gastroenterology
2015 REVIEW
Bifidobacterium longum W11 w zespole jelita nadpobudliwego
· Gastroenterologia Kliniczna. Postępy i Standardy
2014 IN_VITRO
Scanning Electron Microscopy Observation of Adhesion Properties of Bifidobacterium longum W11 and Chromatographic Analysis of Its Exopolysaccaride
· Food and Nutrition Sciences
2007 IN_VITRO
Differential immunomodulatory properties of Bifidobacterium logum strains: relevance to probiotic selection and clinical applications
· Clinical & Experimental Immunology
2006 RCT
Role of gut microflora and probiotic effects in the irritable bowel syndrome.
· PubMed
2006 OBSERVATIONAL
Effect of a symbiotic preparation on the clinical manifestations of irritable bowel syndrome, constipation-variant. Results of an open, uncontrolled multicenter study.
· PubMed
2006 OBSERVATIONAL
Diet and chronic constipation. Benefits of oral supplementation with symbiotic zir fos (Bifidobacterium longum W11 + FOS Actilight).
· PubMed
2004 OBSERVATIONAL
Clinical Experience With Probiotics in the Elderly on Total Enteral Nutrition
· Journal of Clinical Gastroenterology
2019 ANIMAL
Immunomodulatory Effects by Bifidobacterium longum KACC 91563 in Mouse Splenocytes and Macrophages
· Journal of Microbiology and Biotechnology
Browse all 16 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    A SYSTEMATIC MAPPING REVIEW OF IN-VITRO AND IN-VIVO EVIDENCES EXPLORING THE ROLE OF STRAIN-SPECIFIC PROBIOTIC BIFIDOBACTERIUM LONGUM W11
    · International Journal of Pharmaceutical Sciences and Drug Research · 2024
    Source →
  2. [2]
    Differential immunomodulatory properties of Bifidobacterium logum strains: relevance to probiotic selection and clinical applications
    · Clinical & Experimental Immunology · 2007
    PMID 17956582 →
  3. [3]
    Effect of a symbiotic preparation on the clinical manifestations of irritable bowel syndrome, constipation-variant. Results of an open, uncontrolled multicenter study.
    · PubMed · 2006
    PMID 17108864 →