Strain Profile
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Enterococcus faecium M-74
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Enterococcus faecium M-74 is a strain used historically in veterinary probiotic preparations (marketed as Lactiferm) and has been studied primarily in animal models, poultry and piglets, examining growth, bone mineralization, and blood parameters. A small number of human studies exist, including a pilot observational study in cancer patients and a single RCT examining serum cholesterol after one year of use. Enterococcus faecium is classified as a potential opportunistic pathogen in certain clinical contexts. The available evidence for this strain is largely animal-based and early-stage; no established human clinical efficacy has been confirmed. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 15 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 5 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
33 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2014
ANIMAL
2013
ANIMAL
2011
ANIMAL
2011
IN_VITRO
2011
IN_VITRO
2011
IN_VITRO
2011
ANIMAL
2010
ANIMAL
2010
ANIMAL
2009
IN_VITRO
2008
ANIMAL
2006
ANIMAL
2005
RCT
2005
ANIMAL
2005
RCT
2005
RCT
2005
OBSERVATIONAL
2005
OTHER
2004
ANIMAL
2004
ANIMAL
Browse all 33 papers →
Effect of Probiotic Addition in Drinking Water on Body Weight and Body Measurements of Broiler Chickens
· DOAJ (DOAJ: Directory of Open Access Journals)
THE EFFECT OF DIFFERENT PROBIOTIC STRAINS ON FATTENINTHE EFFECT OF DIFFERENT PROBIOTIC STRAINS ON F
· DOAJ (DOAJ: Directory of Open Access Journals)
Effect of Probiotic Strain Enterococcus faecium M74 Supplementation on the Carcass Parameters of Different Hybrid Combination Chickens
· DOAJ (DOAJ: Directory of Open Access Journals)
Effekt der Gefriertrocknung auf Enterococcus faecium
· University of Vienna
Effect of stress on cellular properties of probiotic microorganisms
· University of Vienna
Efficacy of selected probiotic cultures to inhibit Enterobacter sakazakii ATCC 12868 in model reconstituted dairy products
· International Journal of Food Safety Nutrition and Public Health
Effect of probiotic supplementation on selected indices of energy profile and antioxidant status of chickens.
· Journal of Microbiology Biotechnology and Food Sciences
ORIGINAL ARTICLE: Effect of Lactobacillus fermentum and Enterococcus faecium strains on internal milieu, antioxidant status and body weight of broiler chickens
· Journal of Animal Physiology and Animal Nutrition
Effects of Enterococcus faecium M 74 strain on selected blood and production parameters of laying hens
· British Poultry Science
Survey of heat stress response of Enterococcus faecium using fluorimetry and flow cytometry
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Selected Blood Biochemical and Haematological Parameters in Turkeys afteran Experimental Probiotic Enterococcus faecium M-74 Strain Administration
· International Journal of Poultry Science
Comparison of the effects of Enterococcus faecium and aromatic oils from sage and oregano on growth performance and diarrhoeal diseases of weaned pigs
· Biologia
Long-term (56-week) oral administration of probiotic Enterococcus faecium M-74 decreases the expression of sICAM-1 and monocyte CD54, and increases that of lymphocyte CD49d in humans.
· PubMed
The influence of Enterococcus faecium M-74 bacteria on bone mineralization in chickens.
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One-year application of probiotic strain Enterococcus faecium M-74 decreases serum cholesterol levels.
· PubMed
Prevention of febrile neutropenia in cancer patients by probiotic strain Enterococcus faecium M-74. Phase II study
· Supportive Care in Cancer
Prevention of febrile neutropenia in cancer patients by probiotic strain Enterococcus faecium M-74. Pilot study phase I.
· PubMed
Intramucosal bacteria in colon cancer and their elimination by probiotic strainEnterococcus faecium M-74 with organic selenium
· Folia Microbiologica
Effect of probiotic supplementation on the performance and the composition of the intestinal microflora in broilers
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Influence of diet containing lyophilized Enterococcus faecium M-74 with organic selenium on tumor incidence in Apc1638N mice.
· PubMed
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 16026136 →One-year application of probiotic strain Enterococcus faecium M-74 decreases serum cholesterol levels.· PubMed · 2005
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[2]
PMID 16175356 →Prevention of febrile neutropenia in cancer patients by probiotic strain Enterococcus faecium M-74. Phase II study· Supportive Care in Cancer · 2005
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[3]
PMID 16080364 →Long-term (56-week) oral administration of probiotic Enterococcus faecium M-74 decreases the expression of sICAM-1 and monocyte CD54, and increases that of lymphocyte CD49d in humans.· PubMed · 2005
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[4]
PMID 10824413 →[Immunostimulatory and other beneficial health effects of lactic acid bacteria].· PubMed · 2000
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[5]
PMID 10500327 →[Successful modification of human intestinal microflora with oral administration of lactic acid bacteria].· PubMed · 1999
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[6]
PMID 8768254 →Hypocholesterolemic and immunostimulatory effects of orally appliedEnterococcus fœcium M-74 in man· Folia Microbiologica · 1995