Strain Profile · NCBI Strain Taxon 1299318
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Enterococcus faecium L3

◔ Human-origin
Sequenced
Public genome assembly available

Enterococcus faecium strain L3 is a gram-positive lactic acid bacterium. Research includes in vitro studies of its antimicrobial properties and functional characteristics in food applications, animal and observational studies, and randomized controlled trials examining its associations with changes in infection rates and gastrointestinal health, often studied as part of multi-strain probiotic formulations.

Where it's been studied

Share of this strain's 62 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+3 more systems

Symptoms in the research

Share of this strain's 21 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+3 more symptoms

Research

95 papers reference this strain in the probiotic database.

Match confidence
2026 OBSERVATIONAL
STUDY OF THE ACTIVITY OF A POSTBIOTIC BASED ON THE ENTEROCOCCUS FAECIUM L-3 STRAIN TO OPTIMIZE THE QUALITATIVE AND QUANTITATIVE COMPOSITION OF HUMAN MICROBIOTA UNDER CONDITIONS OF LONG-TERM ISOLATION IN CONFINED HABITAT
· Epidemiology and Infectious Diseases
2026 ANIMAL
The effect of a combination of metformin and the probiotic Enterococcus faecium L3 on glucose tolerance and its absorption in the small intestine in rats with type 2 diabetes mellitus
· Сибирский научный медицинский журнал
2024 OBSERVATIONAL
A Controlled, Retrospective, Single-Center Study to Evaluate the Role of a Probiotic Mixture Administered during Pregnancy in Reducing Streptococcus Agalactiae Swab Positivity and the Frequency of Premature Rupture of Amniochorionic Membranes
· Microorganisms
2023 OBSERVATIONAL
KHẢO SÁT HIỆU QUẢ CỦA CHẾ PHẨM PROBIOTIC ENTEROCOCCUS FAECIUM L3 TRÊN NGƯỜI TÌNH NGUYỆN KHỎE MẠNH
· Tạp chí Khoa học và Công nghệ nhiệt đới
2023 ANIMAL
Probiotics and Autoprobiotics in the Treatment of Experimental Vaginitis
· Antibiot Khimioter = Antibiotics and Chemotherapy
2023 ANIMAL
SARS-CoV-2 Spike Protein-Expressing Enterococcus for Oral Vaccination: Immunogenicity and Protection
· Vaccines
2022 RCT
Personalized symbiontic therapy for children with functional digestive disorders
· Experimental and Clinical Gastroenterology
2022 OBSERVATIONAL
Experience of using a probiotic strain of Enterococcus in long-term nutritional support for premature children
· Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)
2022 OBSERVATIONAL
Irritable bowel syndrome therapy in Vietnam with probiotic enterococci
· Experimental and Clinical Gastroenterology
2022 OBSERVATIONAL
The clinical effectiveness of probiotics and autoprobiotics in treatment of Helicobacter pylori-associated dyspepsia
· Russian Journal of Infection and Immunity
2022 RCT
The use of E. faecium probiotic and autoprobiotic in patients with type 2 diabetes mellitus
· HERALD of North-Western State Medical University named after I I Mechnikov
2022 IN_VITRO
Surface expression of SARS-CoV-2 epitopes in Enterococcus faecium L3 for live oral vaccine against new coronavirus infection
· Medical academic journal
2022 RCT
Personalized symbionic therapy of campylobacteriosis protracted course in children
· Experimental and Clinical Gastroenterology
2021 IN_VITRO
The need for individual selection of probiotics containing lactobacilli and enterococci to increase the effectiveness of therapy for campylobacteriosis
· Experimental and Clinical Gastroenterology
2021 RCT
Treatment With a Probiotic Mixture Containing Bifidobacterium Animalis Subsp. Lactis BB12 and Enterococcus Faecium l3 for the Prevention of Allergic Rhinitis in Children: A Randomized Controlled Trial
· Preprints.org
2021 RCT
Treatment with a Probiotic Mixture Containing Bifidobacterium animalis Subsp. Lactis BB12 and Enterococcus faecium L3 for the Prevention of Allergic Rhinitis Symptoms in Children: A Randomized Controlled Trial
· Nutrients
2021 RCT
Use of a probiotic mixture containing Bifidobacterium animalis subsp. lactis BB-12 and Enterococcus faecium L3 as prophylaxis to reduce the incidence of acute gastroenteritis and upper respiratory tract infections in children
· Minerva Pediatrics
2020 RCT
Efficacy and safety of autoprobiotic therapy in patients with type 2 diabetes mellitus
· Medical alphabet
2020 RCT
Impact of a two-bacterial-strain formula, containing Bifidobacterium animalis lactis BB-12 and Enterococcus faecium L3, administered before and after therapy for Helicobacter pylori eradication
· Minerva Gastroenterologica e Dietologica
2020 ANIMAL
THE USE OF A PROBIOTIC STRAIN FOR GASTROENTERITIS IN PIGLETS
· Vestnik Burâtskoj gosudarstvennoj selʹskohozâjstvennoj akademii im. V.R. Fillipova.
Browse all 95 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    The effect of a combination of metformin and the probiotic Enterococcus faecium L3 on glucose tolerance and its absorption in the small intestine in rats with type 2 diabetes mellitus
    · Сибирский научный медицинский журнал · 2026
    Source →
  2. [2]
    A Controlled, Retrospective, Single-Center Study to Evaluate the Role of a Probiotic Mixture Administered during Pregnancy in Reducing Streptococcus Agalactiae Swab Positivity and the Frequency of Premature Rupture of Amniochorionic Membranes
    · Microorganisms · 2024
    PMID 39458288 →
  3. [3]
    Personalized symbionic therapy of campylobacteriosis protracted course in children
    · Experimental and Clinical Gastroenterology · 2022
    Source →
  4. [4]
    Personalized symbiontic therapy for children with functional digestive disorders
    · Experimental and Clinical Gastroenterology · 2022
    Source →
  5. [5]
    The use of E. faecium probiotic and autoprobiotic in patients with type 2 diabetes mellitus
    · HERALD of North-Western State Medical University named after I I Mechnikov · 2022
    Source →
  6. [6]
    Treatment With a Probiotic Mixture Containing Bifidobacterium Animalis Subsp. Lactis BB12 and Enterococcus Faecium l3 for the Prevention of Allergic Rhinitis in Children: A Randomized Controlled Trial
    · Preprints.org · 2021
    Source →
  7. [7]
    Use of a probiotic mixture containing Bifidobacterium animalis subsp. lactis BB-12 and Enterococcus faecium L3 as prophylaxis to reduce the incidence of acute gastroenteritis and upper respiratory tract infections in children
    · Minerva Pediatrics · 2021
    PMID 32506882 →
  8. [8]
    Efficacy and safety of autoprobiotic therapy in patients with type 2 diabetes mellitus
    · Medical alphabet · 2020
    Source →
  9. [9]
    Impact of a two-bacterial-strain formula, containing Bifidobacterium animalis lactis BB-12 and Enterococcus faecium L3, administered before and after therapy for Helicobacter pylori eradication
    · Minerva Gastroenterologica e Dietologica · 2020
    PMID 32272820 →
  10. [10]
    Enterococcus as probiotics: what is the advantage?
    · Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods · 2019
    Source →