Strain Profile
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Enterococcus faecium

◔ Human-origin
Sequenced
Public genome assembly available

Enterococcus faecium (undesignated strain) appears in the research literature primarily in the context of antibiotic resistance and hospital-associated infection rather than probiotic applications. The available papers describe mechanisms of vancomycin and beta-lactam resistance, virulence factor production, mobile genetic elements, and global dissemination of hospital clones, reflecting E. faecium's status as a significant opportunistic pathogen in healthcare settings. This entry represents the species-level taxonomy rather than a specific characterized probiotic strain, and no probiotic evidence is attributed to it.

Where it's been studied

Share of this strain's 233 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+6 more systems

Symptoms in the research

Share of this strain's 38 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+8 more symptoms

Strains of this species

6 strains of Enterococcus faecium in the index, with 209 linked papers between them.

Enterococcus faecium SF68

™ SF68

Enterococcus faecium SF68 has a history of use as a probiotic, particularly in veterinary and some human applications, with research conducted in the context of diarrhea management.

Immune Barrier Adhesion
◔ Human-origin
65 papers 0 comments

Enterococcus faecium M-74

™ M-74

Enterococcus faecium M-74 is a strain used historically in veterinary probiotic preparations (marketed as Lactiferm) and has been studied primarily in animal models, poultry and piglets, examining growth, bone mineraliza…

Metabolic Adhesion Immune
◔ Human-origin
33 papers 0 comments

Enterococcus faecium T-110

™ T-110

Enterococcus faecium T-110 is one component of a three-strain probiotic combination that has been studied in animal models, including a germ-free mouse study examining neurogenesis (the formation of new nerve cells) and …

Metabolic Barrier Immune
◔ Human-origin
4 papers 0 comments

Enterococcus faecium CRL183

™ CRL183

Enterococcus faecium CRL183 is a Brazilian research strain with a body of primarily in vitro and animal evidence.

Survival Metabolic Adhesion
◔ Human-origin
11 papers 0 comments

Enterococcus faecium L3

™ L3

Enterococcus faecium strain L3 is a gram-positive lactic acid bacterium.

Adhesion Immune Barrier
◔ Human-origin
96 papers 0 comments

Enterococcus faecium ZGBP5-52

DEP ZGBP5-52

Enterococcus faecium ZGBP5-52 has been characterized in two 2024–2025 in vitro studies examining its role in milk fermentation, specifically its contribution to volatile flavor compounds and bioactive peptides in artisan…

Metabolic Precision
◔ Human-origin
3 papers 0 comments

Research

811 papers reference this strain in the probiotic database.

Match confidence
2025 WGS
Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium
· Nature Microbiology
2025 REVIEW
Vancomycin-resistant Enterococcus faecium: A current perspective on resilience, adaptation, and the urgent need for novel strategies
· Journal of Global Antimicrobial Resistance
2024 OBSERVATIONAL
Bacteriophage and antibiotic combination therapy for recurrent Enterococcus faecium bacteremia
· mBio
2023 REVIEW
Progress in the application of Enterococcus faecium in animal husbandry
· Frontiers in Cellular and Infection Microbiology
2022 ANIMAL
Administration of microencapsulated Enterococcus faecium ABRIINW.N7 with fructo-oligosaccharides and fenugreek on the mortality of tilapia challenged with Streptococcus agalactiae
· Frontiers in Veterinary Science
2022 WGS
Genomic Surveillance of Vancomycin-Resistant Enterococcus faecium Reveals Spread of a Linear Plasmid Conferring a Nutrient Utilization Advantage
· mBio
2022 ANIMAL
Collateral sensitivity to pleuromutilins in vancomycin-resistant Enterococcus faecium
· Nature Communications
2022 IN_VITRO
Evaluation of Bacteriophage-Antibiotic Combination Therapy for Biofilm-Embedded MDR Enterococcus faecium
· Antibiotics
2022 IN_VITRO
Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium
· Gut Pathogens
2022 OBSERVATIONAL
Interhospital transmission of vancomycin-resistant Enterococcus faecium in Aomori, Japan
· Antimicrobial Resistance and Infection Control
2021 IN_VITRO
Lytic Bacteriophages Facilitate Antibiotic Sensitization of Enterococcus faecium
· Antimicrobial Agents and Chemotherapy
2021 OBSERVATIONAL
Emergence of linezolid-resistance in vancomycin-resistant Enterococcus faecium ST117 associated with increased linezolid-consumption
· International Journal of Medical Microbiology
2021 IN_VITRO
Identification of Lead Compounds against Scm (fms10) in Enterococcus faecium Using Computer Aided Drug Designing
· Life
2021 ANIMAL
Evaluation of the Cholesterol-Lowering Mechanism of Enterococcus faecium Strain 132 and Lactobacillus paracasei Strain 201 in Hypercholesterolemia Rats
· Nutrients
2021 IN_VITRO
Optimization and physicochemical characterization of low molecular levan from Enterococcus faecium MC-5 having potential biological activities
· Process Biochemistry
2021 IN_VITRO
Anticancer and antimicrobial potential of enterocin 12a from Enterococcus faecium
· BMC Microbiology
2021 OBSERVATIONAL
Occurrence of multidrug-resistant Enterococcus faecium isolated from environmental samples
· Letters in Applied Microbiology
2021 META_ANALYSIS
The Global Prevalence of Daptomycin, Tigecycline, and Linezolid-Resistant Enterococcus faecalis and Enterococcus faecium Strains From Human Clinical Samples: A Systematic Review and Meta-Analysis
· Frontiers in Medicine
2021 OBSERVATIONAL
Clinically Applicable System for Rapidly Predicting Enterococcus faecium Susceptibility to Vancomycin
· Microbiology Spectrum
2021 OBSERVATIONAL
Replacement of Enterococcus faecalis by Enterococcus faecium as the predominant enterococcus in UK bacteraemias
· JAC-Antimicrobial Resistance
Browse all 811 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Randomized, Placebo-Controlled, Double-Blind and Open-Label Studies in the Treatment and Prevention of Acute Diarrhea With Enterococcus faecium SF68
    · Frontiers in Medicine · 2020
    PMID 32656217 →
  2. [2]
    Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis
    · eLife · 2019
    PMID 30969170 →
  3. [3]
    Enterococcus faecium SF68 as a model for efficacy and safety evaluation of pharmaceutical probiotics
    · Beneficial Microbes · 2018
    PMID 29633645 →
  4. [4]
    Aging Eye Microbiota in Dry Eye Syndrome in Patients Treated with Enterococcus faecium and Saccharomyces boulardii
    · Current Clinical Pharmacology · 2017
    PMID 28676009 →
  5. [5]
    The influence of probiotic Enterococcus faecium strain L5 on the microbiota and cytokines expression in rats with dysbiosis induced by antibiotics
    · Beneficial Microbes · 2010
    PMID 21831763 →
  6. [6]
    One-year application of probiotic strain Enterococcus faecium M-74 decreases serum cholesterol levels.
    · PubMed · 2005
    PMID 16026136 →
  7. [7]
    Transient Intestinal Carriage after Ingestion of Antibiotic-Resistant Enterococcus faecium from Chicken and Pork
    · New England Journal of Medicine · 2001
    PMID 11642232 →
  8. [8]
    Impact on Human Intestinal Microflora of an Enterococcus faecium Probiotic and Vancomycin
    · Scandinavian Journal of Infectious Diseases · 2000
    PMID 11200372 →
  9. [9]
    Long-term effects of Enterococcus faecium SF68 versus lactulose in the treatment of patients with cirrhosis and grade 1–2 hepatic encephalopathy
    · Journal of Hepatology · 1995
    PMID 8530808 →