Strain Profile
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Enterococcus faecium SF68
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Enterococcus faecium SF68 has a history of use as a probiotic, particularly in veterinary and some human applications, with research conducted in the context of diarrhea management. Randomized controlled trials in dogs and infants have examined acute diarrhea episodes, and animal studies have examined gut microbiota modulation under high-fat diet conditions. E. faecium as a species includes both probiotic strains and hospital-associated pathogenic lineages; the SF68 strain is taxonomically distinct from vancomycin-resistant enterococcal (VRE) clinical isolates. A 2015 commentary reviewed the evidence base and species-level safety concerns, though the literature base for this strain is modest compared to more widely studied genera. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 50 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+4 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 21 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
65 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2025
IN_VITRO
2024
ANIMAL
2024
WGS
2023
ANIMAL
2022
RCT
2022
ANIMAL
2022
IN_VITRO
2021
RCT
2020
ANIMAL
2020
RCT
2019
RCT
2019
RCT
2019
ANIMAL
2018
REVIEW
2018
RCT
2016
RCT
2015
ANIMAL
2015
OTHER
2015
ANIMAL
2015
ANIMAL
Browse all 65 papers →
PSIX-10 Evaluation of a probiotic with psyllium using canine and feline-specific intestinal in vitro fermentation assays.
· Journal of Animal Science
Títuloefecto De Enterococcus Faecium Sf68® Sobre El Microbioma Intestinal Y Los Parámetros De Estrés De Gatos Adultos: Un Estudio Piloto
· SSRN Electronic Journal
An update on the taxonomy and functional properties of the probiotic Enterococcus faecium SF68
· Beneficial Microbes
Dietary Supplementation with the Probiotic SF68 Reinforces Intestinal Epithelial Barrier in Obese Mice by Improving Butyrate Bioavailability
· Molecular Nutrition & Food Research
Effect of Probiotics on Rotavirus and Non-Rotavirus Diarrhea in Infants: Randomized Controlled Trial
· Esculapio
The administration of Enterococcus faecium SF68 counteracts compositional shifts in the gut microbiota of diet-induced obese mice
· Frontiers in Microbiology
Norepinephrine and Serotonin Can Modulate the Behavior of the Probiotic Enterococcus faecium NCIMB10415 towards the Host: Is a Putative Surface Sensor Involved?
· Microorganisms
Protective Effect of Enterococcus faecium SF68 and Saccharomyces boulardii in Acute Severe Diarrhea in Infants: Randomized Controlled Trial
· Esculapio
EFFECTS OF ENTEROCOCCUS FAECIUM (SF68) SUPPLEMENTATION ON THE INNATE IMMUNE DEFENSES AND BLOOD BIOCHEMICAL CHANGES IN PRE-WEANING GOAT KIDS
· The Journal of Animal and Plant Sciences
Randomized, Placebo-Controlled, Double-Blind and Open-Label Studies in the Treatment and Prevention of Acute Diarrhea With Enterococcus faecium SF68
· Frontiers in Medicine
Pilot evaluation of Enterococcus faecium SF68 as adjunctive therapy for oclacitinib‐responsive adult atopic dermatitis in dogs
· Journal of Small Animal Practice
Effect of probiotic Enterococcus faecium SF68 on liver function in healthy dogs
· Journal of Veterinary Internal Medicine
Effects of Enterococcus faecium SF68 on diarrhea rate, intestinal development and morphology of weaned piglets.
· Dongwu yingyang xuebao
Enterococcus faecium SF68 as a model for efficacy and safety evaluation of pharmaceutical probiotics
· Beneficial Microbes
Effect of Enterococcus faecium SF68 on serum cobalamin and folate concentrations in healthy dogs
· Journal of Small Animal Practice
Effect of short‐term probiotic Enterococcus faecium SF68 dietary supplementation in overweight and obese cats without comorbidities
· Veterinary Record Open
Effects of benzoic acid, essential oils and Enterococcus faecium SF68 on growth performance, nutrient digestibility, blood profiles, faecal microbiota and faecal noxious gas emission in weanling pigs
· Journal of Applied Animal Research
Comment on the Safety of Enterococcus faecium SF68
· Journal of Pediatric Gastroenterology and Nutrition
Intramammary tolerance of late lactation Holstein cows towards probiotic Enterococcus faecium SF68
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Intramammary infusion of an Enterococcus faecium SF68 preparation promoted the involution of drying off Holstein cows partly related to neutrophil-associated matrix metalloproteinase 9
· Institutional Repositories DataBase (IRDB)
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Citations
Selected papers that name this strain.
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[1]
PMID 38688481 →An update on the taxonomy and functional properties of the probiotic Enterococcus faecium SF68· Beneficial Microbes · 2024
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[2]
Source →Effect of Probiotics on Rotavirus and Non-Rotavirus Diarrhea in Infants: Randomized Controlled Trial· Esculapio · 2022
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[3]
Source →Protective Effect of Enterococcus faecium SF68 and Saccharomyces boulardii in Acute Severe Diarrhea in Infants: Randomized Controlled Trial· Esculapio · 2021
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[4]
PMID 32656217 →Randomized, Placebo-Controlled, Double-Blind and Open-Label Studies in the Treatment and Prevention of Acute Diarrhea With Enterococcus faecium SF68· Frontiers in Medicine · 2020
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[5]
PMID 29633645 →Enterococcus faecium SF68 as a model for efficacy and safety evaluation of pharmaceutical probiotics· Beneficial Microbes · 2018