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Escherichia coli M-17

DEP M-17
◔ Human-origin
Sequenced
Public genome assembly available

Escherichia coli M-17 is a non-pathogenic E. coli strain used historically as a probiotic in Eastern European medicine, particularly in products such as Colibacterin. The majority of its research record consists of in vitro studies examining antagonistic activity against other bacteria and characterization of its surface and lipopolysaccharide properties. One small randomized controlled trial investigated it in patients with irritable bowel syndrome accompanied by proximal small bowel inflammation; this represents an isolated study that has not been replicated at scale. E. coli M-17 is taxonomically distinct from pathogenic E. coli strains and has a long history of clinical use, though it is not widely studied in modern probiotic research outside of Eastern Europe. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 24 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 4 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

59 papers reference this strain in the probiotic database.

Match confidence
2026 IN_VITRO
Avirulent Probiotic Strain of Escherichia coli, Producing the B-Subunit of Cholera Toxin: Obtainment, Stability of Inheritance, and Expression of the Cloned ctxB Gene
· Problems of Particularly Dangerous Infections
2025 RCT
Preliminary Evidence for Sex-Specific Trends in Probiotic Modulation of Gut Saccharibacteria in Familial Mediterranean Fever Patients: Effects of Lactobacillus acidophilus INMIA 9602 Er 317/402 and Escherichia coli M-17
· International Journal of Molecular Sciences
2022 IN_VITRO
ANTAGONISTIC ACTIVITY OF IMMOBILIZED PROBIOTICS STORED AT LOW TEMPERATURES
· Актуальні проблеми сучасної медицини Вісник Української медичної стоматологічної академії
2020 IN_VITRO
An accelerated method for determining «self/non-self» microorganisms in the agglutination reaction
· Russian Journal of Infection and Immunity
2020 IN_VITRO
VIABILITY OF PROBIOTIC STRAINS OF MICROORGANISMS AND THEIR ADHESION TO HUMAN ERYTHROCYTES AFTER IMMOBILIZATION IN ALGINATE GEL AND STORAGE AT DIFFERENT LOW TEMPERATURES
· Актуальні проблеми сучасної медицини Вісник Української медичної стоматологічної академії
2019 IN_VITRO
Effects of food additives on survival of strains Escherichia, Enterococcus, Bifidobacteria and Lactobacillus
· Proceedings of the National Academy of Sciences of Belarus Medical series
2019 WGS
Genetic Analysis of the Probiotic Strain Escherichia coli M-17 and the Potentially Probiotic Strain Escherichia coli BM
Genetic Analysis of the Probiotic Strain Escheriсhia coli M-17 and the Potentially Probiotic Strain Escheriсhia coli ВМ
· Microbiology
2017 WGS
PHENOTYPIC AND GENOTYPIC CHARACTERISTICS OF E. COLI M-17 THE PROBIOTIC STRAIN
· Современные проблемы науки и образования (Modern Problems of Science and Education)
2016 IN_VITRO
Cell surface properties of probiotic Escherichia coli strains
· European Microscopy Congress 2016: Proceedings
2016 IN_VITRO
INTERMICROBIAL «SELF-NON-SELF» DISCRIMINATION IN «DOMINANT-ASSO-CIANT» PAIR OF PROBIOTIC STRAINS OF ESCHERICHIA COLI M-17 AND E.COLI LEGM-18
· Journal of microbiology epidemiology immunobiology
2016 IN_VITRO
[INTERMICROBIAL <<SELF-NON-SELF>> DISCRIMINATION IN <<DOMINANT-ASSOCIANT>> PAIR OF PROBIOTIC STRAINS OF ESCHERICHIA COLI M-17 AND E.COLI LEGM-18].
· PubMed
2015 IN_VITRO
Effect of storage temperatures on Escherichia coli M-17 cell viability
· Problems of Cryobiology and Cryomedicine
2013 IN_VITRO
Viability of Probiotic Escherichia coli M-17 After Immobilization in Polysaccharide Gels and Storage at Various Temperatures
Сохранность пробиотика Escherichia Coli M-17 после иммобилизации в полисахаридных гелях и хранения при различных температурах
· Medicine Today and Tomorrow
2012 IN_VITRO
[Escherichia coli M-17 lipopolysaccharide].
· PubMed
2012 IN_VITRO
Comparative Analysis of the Composition and Dynamics of Amino Acids Released by Bacteria into the Culture Medium Using Escherichia coli and Salmonella enteritidis as Examples
Сравнительный анализ состава и динамики аминокислот, выделяемых бактериями в среду культивирования на примере выращивания Escherichia coli и Salmonella enteritidis
· Политематический сетевой электронный научный журнал Кубанского государственного аграрного университета
2012 IN_VITRO
[Presence of genes of genotoxin associated with pks pathogenicity island in Escherichia coli M-17 probiotic strain].
· PubMed
2011 IN_VITRO
Effect of Heavy Metals on the Growth of Probiotic Strains E. coli M-17, E. faecium, L. acidophilus, L. bulgaricus LB 51, and Bacteria of the Genus Bacillus In Vitro
Влияние тяжелых металлов на рост пробиотических штаммов E. coli m 17, E. faecium, L. acidophillus, L. bulgaricus LB 51 и бактерии рода Bacillus в условиях in vitro
· Вестник Оренбургского государственного университета
2010 IN_VITRO
[Using of Spherocelle sorbents for construction of immobilized probiotics].
· PubMed
2009 IN_VITRO
Investigation of the interaction of Bifidobacterium bifidum 1 and Escherichia coli M-17 in the bificol praparation during their simultaneous cultivation
· DOAJ (DOAJ: Directory of Open Access Journals)
2006 IN_VITRO
Comparison of the Antibactericidal Activity of E. coli M-17 from the Colibacterin Preparation and Bacterial Cultures Isolated in Dysbiosis
Сравнение антибактерицидной активности E. coli M-17 из препарата колибактерин и культур бактерий, выделенных при дисбактериозе
· Кубанский научный медицинский вестник
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Citations

Selected papers that name this strain.

  1. [1]
    Genetic Analysis of the Probiotic Strain Escherichia coli M-17 and the Potentially Probiotic Strain Escherichia coli BM
    Genetic Analysis of the Probiotic Strain Escheriсhia coli M-17 and the Potentially Probiotic Strain Escheriсhia coli ВМ
    · Microbiology · 2019
    Source →
  2. [2]
    An Open Label, High Dose Prospective Trial of the Safety of the Probiotic E. coli Strain M-17 in Healthy Volunteers
    · The American Journal of Gastroenterology · 2006
    Source →