Strain Profile
· NCBI Strain Taxon
83333
NCBI Taxonomy's node for this specific strain. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Escherichia coli K12
DEP
K12
◔
Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
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Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Escherichia coli K12 is a non-pathogenic laboratory reference strain that has been central to molecular biology and genetics research since the mid-20th century. It appears in this index exclusively as a reference organism, used to test antimicrobial activity, plasmid transfer dynamics, disinfection efficacy, and other experimental conditions, rather than as a probiotic or health-promoting microorganism. It has no probiotic role, and its presence in the literature reflects its status as a standard laboratory tool. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 136 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+3 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 44 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+1 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
541 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
IN_VITRO
2026
ANIMAL
2026
ANIMAL
2026
OTHER
2026
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
ANIMAL
2025
ANIMAL
2025
IN_VITRO
2024
ANIMAL
2023
IN_VITRO
2023
ANIMAL
2023
IN_VITRO
2022
IN_VITRO
2020
ANIMAL
2020
IN_VITRO
2020
IN_VITRO
Browse all 541 papers →
Disruptions in outer membrane-peptidoglycan interactions enhance bile salt resistance in O-antigen-producing E. coli
· Newcastle University ePrints (Newcastle Univesity)
A strong-to-weak interaction shift during microbiome succession is coupled to colonizer-dependent antimicrobial resistance
· bioRxiv (Cold Spring Harbor Laboratory)
Genetic mechanisms underlying the increase of Adherent-Invasive E. coli in Inflammatory Bowel Disease
· Journal of Crohn s and Colitis
Benchmarking strain-level profiling of Escherichia coli in short-read gut metagenomes
· bioRxiv (Cold Spring Harbor Laboratory)
E. coli K12 as a dysbiosis-driven catalyst in colorectal cancer: In silico identification of cross-species protein-protein interactions
· Medicine in Microecology
A noncanonical polyamine from bacteria antagonizes host mitochondrial function
· Nature Communications
Genetiği değiştirilmiş bakterilerden üretilen bütirik asitin RNA bağlayıcı proteinlerin düzenlenmesi üzerindeki etkisi.
· OpenMETU (Middle East Technical University)
Investigating stringent response-mediated tolerance to non-thermal plasma in Escherichia coli
·
Resistance Development in Escherichia coli Against Far-UVC Irradiation
· Current Directions in Biomedical Engineering
Biohybrid Living Material with Antibacterial and Regenerating Properties Based on Probiotic Bacteria Stress Metabolism Modulation
· Macromolecular Bioscience
Aerosolization and dispersion of bacteria on hands by hand dryers during hand drying activities
· Aerosol Science and Technology
A 3D-Printed Capillary Tube Holder for High-Throughput Chemotaxis Assays
· bioRxiv (Cold Spring Harbor Laboratory)
The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens
· Journal of World s Poultry Research
In Silico and In Vitro Investigation of the Distribution and Expression of Key Genes in the Fucose Operon of Escherichia coli
· Microorganisms
Effect of early postnatal supplementation by probiotic bacteria Escherichia coli O83:K24:H31 on proportional and fucntional characteristics of selected cellular population
· Digital Repository (National Repository of Grey Literature)
Toxicity of per- and polyfluoroalkyl substances to microorganisms in confined hydrogel structures
· Journal of Hazardous Materials
Scan4CFU: Low-cost, open-source bacterial colony tracking over large areas and extended incubation times
· Harvard Dataverse
INFLUENCE OF ANTIBACTERIAL FACTORS ON THE MIXED CULTURE OF ESCHERISCHIA COLI AND STAPHYLOCOCCUS EPIDERMIDIS UNDER CONDITIONS OF INCREASED OSMOTIC PRESSURE
· Вестник Пермского университета Серия «Биология»=Bulletin of Perm University Biology
Escherichia coli K12 Upregulates Programmed Cell Death Ligand 1 (PD-L1) Expression in Gamma Interferon-Sensitized Intestinal Epithelial Cells via the NF-κB Pathway
· Infection and Immunity
Evaluation of Garlic-Resistance in E. coli (strain K12)
· Journal of Student Research
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Citations
Selected papers that name this strain.
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[1]
PMID 6355313 →Recombinant DNA Risk Assessment Studies in Humans: Efficacy of Poorly Mobilizable Plasmids in Biologic Containment· The Journal of Infectious Diseases · 1983