Faecalibacterium prausnitzii A2-165
Faecalibacterium prausnitzii A2-165 is a research reference strain of one of the most abundant and scientifically studied commensal bacteria in the healthy human gut. In vitro studies have examined this strain's butyrate production (a short-chain fatty acid that fuels intestinal lining cells), metabolite production, and interleukin-10 signaling pathways in immune cells. Animal model studies have examined this strain in models of gut inflammation. F. prausnitzii is not currently available as a commercial probiotic supplement — it is an obligate anaerobe that is highly oxygen-sensitive and technically challenging to formulate — so it is primarily a subject of basic and translational research rather than a product-ready strain. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 53 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+1 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 24 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
60 papers reference this strain in the probiotic database.
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Citations
Selected papers that name this strain.
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[1]
Source →The Secreted Metabolite Isopentenyladenine from Faecalibacterium prausnitzii Mitigates Gut Inflammation· bioRxiv (Cold Spring Harbor Laboratory) · 2025
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[2]
PMID 26725514 →Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses· Scientific Reports · 2016
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[3]
Source →Interactions of commensal bacteria with the host immune system· · 2013