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Eubacterium rectale

◔ Human-origin
Sequenced
Public genome assembly available

Eubacterium rectale is a gram-positive, obligate anaerobe and prominent butyrate-producing member of the human gut microbiota, where it is typically one of the more abundant bacterial species. It is not a recognized commercial probiotic and is not used in supplements; research on this organism focuses on its ecological role in the gut ecosystem rather than therapeutic applications. Its capacity to ferment resistant starches and produce butyrate, a short-chain fatty acid used as fuel by colonic cells, has been documented in laboratory and animal-model settings. E. rectale abundance has been studied in relation to gut health indicators and has been examined across several gastrointestinal conditions, using observational and correlational study designs. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 328 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+4 more systems

Symptoms in the research

Share of this strain's 112 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+13 more symptoms

Research

664 papers reference this strain in the probiotic database.

Match confidence
2026 ANIMAL
The Eubacterium Rectale Derived Extracellular Vesicles Alleviate Cancer Cachexia Induced Lipolysis by Inhibiting Macrophage Polarization
· Journal of Extracellular Vesicles
2026 ANIMAL
Mechanistic insights into cordycepin-enhanced CTLA-4 blockade efficacy via Eubacterium rectale-mediated immunomodulation in colon cancer
· International Immunopharmacology
2026 ANIMAL
The influence of selected antioxidants on the growth and metabolism of Eubacterium rectale
· Repository of the University of Ljubljana (University of Ljubljana)
2026 ANIMAL
Eubacterium rectale Mitigates Inflammatory Bowel Disease via Modulation of Glutamine Metabolism Through the GLS2 and NF-κB Pathway
· npj Science of Food
2026 ANIMAL
Butyrate-producing Eubacterium rectale inhibits gastric carcinogenesis and augments the efficacy of immunotherapy
· Journal of Translational Medicine
2025 IN_VITRO
Sulfoglycolysis sustains Eubacterium rectale in low-fiber diets
· Journal of Biological Chemistry
2025 OBSERVATIONAL
IDDF2025-ABS-0256 Effect and mechanism of eubacterium rectale-derived glutamine on intestinal mucosal repair via the GLS2/NF-κB pathway
·
2025 ANIMAL
From gut to joint: the protective impact of Eubacterium rectale on rheumatoid arthritis
· Frontiers in Immunology
2025 ANIMAL
Data Sheet 1_From gut to joint: the protective impact of Eubacterium rectale on rheumatoid arthritis.pdf
· Figshare
2025 RCT
Potential benefits of Soymilk- burkina (Agbenu) consumption on gut health of women of reproductive age
· bioRxiv (Cold Spring Harbor Laboratory)
2024 OBSERVATIONAL
Eubacterium rectale is a potential marker of altered gut microbiota in psoriasis and psoriatic arthritis
· Microbiology Spectrum
2024 RCT
The causal relationship between Eubacterium and constipation: a Mendelian randomization study
· Research Square
2024 ANIMAL
Eubacterium rectale detoxification mechanism increases resilience of the gut environment
· bioRxiv (Cold Spring Harbor Laboratory)
2024 OTHER
Association of gut microbiota with lactose intolerance and coeliac disease: a two-sample Mendelian randomization study
· Frontiers in Nutrition
2024 ANIMAL
Immunomodulatory Effects of a Probiotic Mixture: Alleviating Colitis in a Mouse Model through Modulation of Cell Activation Markers and the Gut Microbiota
· International Journal of Molecular Sciences
2024 OTHER
Anti-inflammatory Effects of Membrane Vesicles from Eubacterium rectale via the NLRP3 Signal Pathway
· Probiotics and Antimicrobial Proteins
2024 ANIMAL
Gut microbiota‐directed dietary factors enhance exercise performance in mice
· Food Frontiers
2023 ANIMAL
Eubacterium rectale Improves the Efficacy of Anti-PD1 Immunotherapy in Melanoma via l-Serine-Mediated NK Cell Activation
· Research
2023 OBSERVATIONAL
72 Eubacterium rectale is a key marker of altered gut microbiota in psoriasis and psoriatic arthritis
· Journal of Investigative Dermatology
2023 OTHER
A mathematical model of Bacteroides thetaiotaomicron, Methanobrevibacter smithii, and Eubacterium rectale interactions in the human gut
· Scientific Reports
Browse all 664 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    The influence of selected antioxidants on the growth and metabolism of Eubacterium rectale
    · Repository of the University of Ljubljana (University of Ljubljana) · 2026
    Source →
  2. [2]
    Effects of Clostridium butyricum Capsules Combined with Rosuvastatin on IntestinalFlora, Lipid Metabolism, Liver Function and Inflammation in NAFLD Patients
    · Cellular and Molecular Biology · 2022
    PMID 35869734 →
  3. [3]
    Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale
    · Molecular Microbiology · 2014
    PMID 25388295 →
  4. [4]
    Gut microbiome composition is linked to whole grain-induced immunological improvements
    · The ISME Journal · 2012
    PMID 23038174 →
  5. [5]
    Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine
    · FEMS Microbiology Letters · 2009
    PMID 19222573 →
  6. [6]
    Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
    · Proceedings of the National Academy of Sciences · 2009
    PMID 19321416 →