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Lactobacillus acidophilus LA-1

◐ Food-origin
Sequenced
Public genome assembly available

Lactobacillus acidophilus LA-1 is a well-known probiotic strain with a research history dating to the 1990s, studied primarily through in vitro and animal model experiments. Laboratory work has documented bacteriocin production and adhesion to intestinal epithelial cells, including studies of attachment competition with enterovirulent bacteria. Animal model studies have examined immune and inflammatory modulation, including in the context of arthritis and colon health. Strain-specific human clinical trial evidence for LA-1 is limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 5 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 3 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

13 papers reference this strain in the probiotic database.

Match confidence
2010 IN_VITRO
Survival of Lactobacillus acidophilus Encapsulated as Freeze-Dried Culture under Extreme Conditions
· International Conference on Bioinformatics and Biomedical Engineering
2010 IN_VITRO
Optimization of the whey medium of Lactobacillus acidophilus by response surface methodology
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2009 IN_VITRO
Determination of Antibacterial Activity and Molecular Weight of Polypeptide Produceds by Two Strains of Lactobacillus acidophilus
· Food Science
1998 ANIMAL
Variable biotherapeutic effects of Lactobacillus acidophilus isolates on orogastric and systemic candidiasis in immunodeficient mice.
· PubMed
1997 IN_VITRO
Characteristics of bacteriocin produced by Lactobacillus acidophilus LA-1
· International Dairy Journal
1994 IN_VITRO
Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria.
· Gut
2025 OBSERVATIONAL
Storage Temperature Effects on Bacillus Spores and Lactobacillus acidophilus Viability
· International Journal of Food Science
2020 ANIMAL
Combinatmarion treatment with Lactobacillus acidophilus LA-1, vitamin B, and curcumin ameliorates the progression of osteoarthritis by inhibiting the pro-inflammatory mediators
· Immunology Letters
2010 ANIMAL
Preventive effects of yogurt on DMH-induced preneoplastic lesions of colon in F344 rats
· Taipei Medical University Repository
2006 IN_VITRO
Producción de leche fermentada utilizando bacterias probióticas (Lactobacillus acidophilus, Bifidobacterium lactís y Streptococcus thermophilus) con leche de cabra y de vaca
· Ciencia e Investigación
2001 IN_VITRO
In vitro adherence properties of Lactobacillus rhamnosus DR20 and Bifidobacterium lactis DR10 strains and their antagonistic activity against an enterotoxigenic Escherichia coli
· International Journal of Food Microbiology
1999 IN_VITRO
Isolation and identification of lactobacilli from novel-type probiotic and mild yoghurts and their stability during refrigerated storage
· International Journal of Food Microbiology
1998 OTHER
Selection and Characterisation of Lactobacillus and Bifidobacterium Strains for Use as Probiotics
· International Dairy Journal
Browse all 13 papers →

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