Strain Profile
Save
Lactobacillus acidophilus DDS-1
◐
Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus acidophilus DDS-1 is a human-origin probiotic strain with one of the broader clinical research bases among L. acidophilus strains. Randomized controlled trials (RCTs) have examined its use in the context of functional constipation in children, irritable bowel syndrome in adults, and gut microbiota in aging animal models. In vitro comparisons have examined DDS-1 relative to plant- and dairy-derived competitors on probiotic functional markers. The body of human RCT evidence is still growing. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 23 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 12 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
27 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2025
REVIEW
2025
RCT
2023
META_ANALYSIS
2022
ANIMAL
2022
RCT
2020
RCT
2019
REVIEW
2019
ANIMAL
2018
ANIMAL
2018
IN_VITRO
2018
ANIMAL
2016
RCT
2012
RCT
2012
ANIMAL
2007
IN_VITRO
2026
REVIEW
2026
REVIEW
2025
ANIMAL
2025
IN_VITRO
2024
REVIEW
Browse all 27 papers →
Clinical Evidence for Microbiome Support
·
Targeted probiotics Lactobacillus acidophilus DDS-1® and Bifidobacterium lactis UABla-12™ (BB-12) eliminate irritable bowel syndrome and associated stress and dermatological conditions in adults and children
· Experimental and Clinical Gastroenterology
Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis
· Nutrients
Lactobacillus acidophilus DDS-1 Modulates the Gut Microbial Co-Occurrence Networks in Aging Mice
· Nutrients
Impact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial
· Frontiers in Microbiology
Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial
· Nutrients
Risk Assessment of Specific Strains of Lactobacillus acidophilus Used as "Other Substances"
· European Journal of Nutrition & Food Safety
Investigation on the utilization of beneficial microbes in modulating the gut microbiota and metabolic profiles in ageing
· UTAS Research Repository
Luminal basic science
· Journal of Gastroenterology and Hepatology
A human origin strain Lactobacillus acidophilus DDS-1 exhibits superior in vitro probiotic efficacy in comparison to plant or dairy origin probiotics
· International Journal of Medical Sciences
Lactobacillus acidophilus DDS-1 Modulates the Gut Microbiota and Improves Metabolic Profiles in Aging Mice
· Nutrients
Efficacy of Lactobacillus Acidophilus DDS-1, Lactobacillus Bulgaricus, Bifidobacterium Infantis in the Prevention of Necrotizing Enterocolitis in Preterm Neonates
· Annals of Punjab Medical College (APMC)
Role of probiotics in attenuation of acute respiratory tract infections in preschool and primary school children
·
Επίδραση των προβιοτικών στην εντερική ατροφία μετά από στέρηση τροφής στον επίμυ
· National Archive of Doctoral Theses (National Documentation Center (Greece))
Characteristics and Immunostimulatory Activity of Lactic Acid Bacterial Strains as Probiotics
Probiotics로서의 젖산균주의 특성 및 면역활성
· Korean Journal of Food Science and Technology
COMPARISON OF THE ROLES OF PROBIOTICS, PREBIOTICS, AND SYNBIOTICS IN THE MANAGEMENT OF IRRITABLE BOWEL SYNDROME: A REVIEW OF RECENT EVIDENCE
· International Journal of Innovative Technologies in Social Science
EFFECTS OF LACTOBACILLUS AND BIFIDOBACTERIUM PROBIOTICS ON GUT MICROBIAL FERMENTATION IN LACTOSE INTOLERANCE: A SYSTEMATIC REVIEW
· International Journal of Engineering Technology Research & Management
Modulating oral microbiota ameliorates hypobaric hypoxia-induced anxiety- and depression-like behaviors in mice
· World Journal of Psychiatry
Tapioca-resistant maltodextrin enhances probiotic survival more effectively than commercial prebiotics under simulated gastrointestinal conditions
· Food Bioscience
EFICÁCIA E SEGURANÇA DOS PROBIÓTICOS NO MANEJO DA SÍNDROME DO INTESTINO IRRITÁVEL: UMA REVISÃO BASEADA EM EVIDÊNCIAS RECENTES
· Revista Foco
Discussion
Be the first to comment.
Sign in to join the discussion.
No comments yet.
Citations
Selected papers that name this strain.
-
[1]
Source →EFFECTS OF LACTOBACILLUS AND BIFIDOBACTERIUM PROBIOTICS ON GUT MICROBIAL FERMENTATION IN LACTOSE INTOLERANCE: A SYSTEMATIC REVIEW· International Journal of Engineering Technology Research & Management · 2026
-
[2]
Source →COMPARISON OF THE ROLES OF PROBIOTICS, PREBIOTICS, AND SYNBIOTICS IN THE MANAGEMENT OF IRRITABLE BOWEL SYNDROME: A REVIEW OF RECENT EVIDENCE· International Journal of Innovative Technologies in Social Science · 2026
-
[3]
PMID 37686889 →Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis· Nutrients · 2023
-
[4]
PMID 32019158 →Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial· Nutrients · 2020
-
[5]
Source →Efficacy of Lactobacillus Acidophilus DDS-1, Lactobacillus Bulgaricus, Bifidobacterium Infantis in the Prevention of Necrotizing Enterocolitis in Preterm Neonates· Annals of Punjab Medical College (APMC) · 2016