Strain Profile
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Lactobacillus acidophilus
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus acidophilus is one of the most studied lactic acid bacteria, with research dating back decades documenting its ability to survive the harsh conditions of the gastrointestinal tract, including acid and bile exposure, that any orally consumed probiotic must endure. Laboratory and animal studies have documented bacteriocin production, including lactacin B and lactacin F, and their activity against competing pathogens in vitro. The evidence base for L. acidophilus is largely drawn from in vitro and animal research, with earlier reviews characterizing its biochemical and technological properties rather than establishing clinical outcomes in humans. Rigorous human trials confirming specific health benefits remain limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 5,851 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 2,072 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
16417 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
RCT
OTHER
IN_VITRO
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
IN_VITRO
2026
IN_VITRO
2026
ANIMAL
2026
IN_VITRO
2026
IN_VITRO
2026
ANIMAL
2026
RCT
2026
ANIMAL
2026
OTHER
2026
OTHER
2026
IN_VITRO
2026
ANIMAL
Browse all 16,417 papers →
Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult atopic dermatitis patients
· Institutional Repositories DataBase (IRDB)
Optimization of Cultivation Conditions for Lactobacillus acidophilus Strain for Lactic Acid Production During Molasses Fermentation
Оптимизация условий культивирования штамма Lactobacillus acidophilus для получения молочной кислоты при ферментации мелассы
· CyberLeninK (CyberLeninka)
Isolation and Antibacterial Characteristics of Lactic Acid Bacteria Showing Antibacterial Activity against Food Contaminating Bacteria
食品汚染細菌に対して抗菌活性を示す乳酸菌の分離とその抗菌特性
· Institutional Repositories DataBase (IRDB)
Synergistic role of lactic acid bacteria and yeast in enhancing rice beer production
· Biochemical and Cellular Archives/Biochemical and cellular archives
Impact of Lactobacillus-Fermented Plantain Peel on Rat Body Mass Indices
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Short-Chain Fatty Acid Modulation in Chick Gut using Lactobacillus-Fermented Corn and Bean Chaff: A Prebiotic Approach
· IPS Journal of Biotechnology and Applied Biochemistry
Toward clinical translation: montmorillonite-enhanced Lactobacillus biofilm alleviates colitis by modulating the gut microbiota–bile acid axis
· Materials Today Bio
Corollary of Lactobacillus Fermented Plantain Peel on Growth Performance of Rats
· IPS Journal of Nutrition and Food Science
Biological Control of Listeria monocytogenes Growth in Fermented Buttermilk Enriched with Microfiltration Retentate
· Foods
Genitourinary syndrome of menopause: efficacy and safety of vaginal combination therapy. A prospective study
· GYNECOLOGY
Bioactive Metabolites from Lactobacillus acidophilus-Fermented Products Mitigate Carbon Tetrachloride–Induced Liver Injury: Biochemical and In Silico Insights
· Current Developments in Nutrition
The SlpX protein of Lactobacillus acidophilus CICC6074 has anti‐inflammatory properties and protects Caco ‐2 intestinal epithelial cells from TNF ‐α‐induced barrier damage
· Journal of the Science of Food and Agriculture
In vitro prebiotic assessment of pectin, inulin and fructooligosaccharide on probiotic lactic acid bacteria
· International Journal of Agriculture and Food Science
Modulation of Short-Chain Fatty Acid Levels in Chick Gut Using Lactobacillus-Fermented Chicken Feather and Bean Chaff: Implications for Poultry Health
· IPS Interdisciplinary Journal of Biological Sciences
Application of Lactobacillus-Derived Bacteriocins to Control Escherichia coli O157:H7 in Food Systems
· Zenodo (CERN European Organization for Nuclear Research)
Combined fortification of yogurt with grape pomace pectic oligosaccharides and encapsulated probiotics
· Scientific Reports
Biogenic Silver Nanoparticles as a Tool for Antifungal Control and Biosafety of the Environment
БІОГЕННІ НАНОЧАСТКИ СРІБЛА ЯК ІНСТРУМЕНТ АНТИФУНГАЛЬНОГО КОНТРОЛЮ ТА БІОБЕЗПЕКИ ДОВКІЛЛЯ
· Technologies and Engineering
Lactobacillus-Fermented Yam Peel Supplementation: Impact on Organ Weight and Leukocyte Indices in Broiler Chicks
· IPS Journal of Applied Microbiology and Biotechnology
Anatomical and histochemical findings of Andean tuber peels
· Lilloa
Evaluating the Prebiotic Effects of Fermented Cocoyam Peel and Fish Meal on Broiler Chick Performance
·
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →Dietary nano-encapsulated Nigella sativa oil and Lactobacillus acidophilus enhance performance, antioxidant status, and gut health in heat-stressed growing rabbits· Italian Journal of Animal Science · 2026
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[2]
Source →Clinical and Translational Evaluation of a Lactobacillus Acidophilus Respiratory Mucosal Barrier Platform· Frontiers in Sustainable Development · 2026
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[3]
PMID 41698905 →Lactobacillus acidophilus KBL409 improves serum indoxyl sulfate via gut microbial changes in a human study· npj Science of Food · 2026
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[4]
Source →The combination of Lactobacillus acidophilus DSMZ 26280 and Limosilactobacillus reuteri DSMZ 25441 has an impact on clinical course and gut microbiota of children with acute infectious diarrhea· Frontiers in Microbiology · 2026
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[5]
PMID 42141695 →Probiotic Blend of Lactobacillus acidophilus LA‐5 and Bifidobacterium animalis ssp. Lactis BB‐12 in Non‐Constipated Irritable Bowel Syndrome: A Double‐Blind Randomized Placebo‐Controlled Trial· Journal of Gastroenterology and Hepatology · 2026
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[6]
PMID 41693686 →Probiotic Supplementation as an Adjuvant Therapy in Pediatric Drug‐Resistant Epilepsy: A Double‐Blind Placebo‐Controlled Trial· Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · 2026
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[7]
PMID 42182865 →Toward clinical translation: montmorillonite-enhanced Lactobacillus biofilm alleviates colitis by modulating the gut microbiota–bile acid axis· Materials Today Bio · 2026
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[8]
PMID 41520710 →Effect of probiotic strain, duration, and dose on preventing ICU-acquired infection: A scoping review· International Journal of Antimicrobial Agents · 2026
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[9]
Source →Probiotics with ABCG2 expression ability and gut microbiota homeostasis exhibit anti-hyperuricemia potential by promoting uric acid excretion· Journal of Functional Foods · 2025
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[10]
PMID 40422866 →Probiotic Supplementation Improves Glucose Homeostasis and Modulates Interleukin (IL)-21 and IL-22 Levels in Pediatric Patients with Type 1 Diabetes: A Randomized Placebo-Controlled Trial· Metabolites · 2025