Strain Profile
· NCBI Strain Taxon
1314884
NCBI Taxonomy's node for this specific strain. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
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Lactobacillus acidophilus La-14
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
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Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus acidophilus LA-14 is a well-characterized probiotic strain with a body of research spanning immune function, digestive health, and encapsulation stability. A 2008 double-blind randomized controlled trial in healthy adults examined specific immune responses, and animal studies have examined the strain in the context of bacterial vaginosis and Helicobacter pylori colonization, though these have not been replicated in controlled human trials for those specific outcomes. Preliminary research, based on observational data from a synbiotic formulation studied in non-dialysis kidney disease patients, has also examined symptoms associated with antibiotic use. Strain-level human clinical evidence remains limited, and further controlled trials would be needed before conclusions can be drawn. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 39 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+4 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 17 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
60 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
ANIMAL
2026
IN_VITRO
2026
IN_VITRO
2025
IN_VITRO
2025
IN_VITRO
2025
OBSERVATIONAL
2024
IN_VITRO
2024
IN_VITRO
2024
IN_VITRO
2023
RCT
2023
REVIEW
2023
IN_VITRO
2023
ANIMAL
2023
ANIMAL
2023
OBSERVATIONAL
2023
RCT
2022
REVIEW
2021
IN_VITRO
2021
ANIMAL
2021
IN_VITRO
Browse all 60 papers →
Modulation of TLR4, hBD-2, and hBD-3 expression and hepatic tissue response by systemic probiotics in experimental apical periodontitis in rats
· Journal of Applied Oral Science
Anatomical and histochemical findings of Andean tuber peels
· Lilloa
Comportamento de cepas distintas de Lactobacillus acidophilus em queijo petit-suisse
· Archivos Latinoamericanos de Nutrición
Fermentation of Sapodilla juice with Lactobacillus acidophilus: Fermentation kinetics and evaluation of functional properties
· Journal of Food Science
Tradescantia spathacea extract as biostimulating in growth and biological activities of Lactobacillus acidophilus and Lacticaseibacillus rhamnosus
· Ecosistemas y Recursos Agropecuarios
The Impact of a 10-Month Synbiotic Intake on eGFR, Uremic Toxins, Oxidative Stress, and Inflammatory Markers in Non-Dialysis Chronic Kidney Disease Patients: A Prospective, Non-Randomized, Placebo-Controlled Study
· Medicina
Viability of Probiotic Strains in Moringa Aqueous Extract-Fortified Low-Fat Yogurt
· Journal of the Advances in Agricultural Researches/Journal of the Advances in Agricultural Researches
Encapsulation of Lactobacillus acidophilus or Bifidobacterium longum Using Whey Protein Concentrate and Fructans as Wall Materials: Properties, Stability, and Viability in Simulated Gastrointestinal Tests
· ACS Food Science & Technology
Antagonistic and antibacterial activity of Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 included in the oral probiotic
· Journal of obstetrics and women s diseases
A Healthy Vaginal Microbiota Remains Stable during Oral Probiotic Supplementation: A Randomised Controlled Trial
· Microorganisms
Antibacterial, probiotic and immunomodulatory properties of L. acidophilus La‑14
· Medical alphabet
Viability of Lactobacillus acidophilus La-14 included in spray-dried microdiets for fish larvae
· Research Square
Probiotic Lactobacillus Acidophilus La-14 as Feed Additive Substitute for Antibiotic Therapy in Broilers
· Advances in health sciences research/Advances in Health Sciences Research
Lactobacillus acidophilus NCFM and Lactiplantibacillus plantarum Lp-115 inhibit Helicobacter pylori colonization and gastric inflammation in a murine model
· Frontiers in Cellular and Infection Microbiology
The Effect of Synbiotic Supplementation on Uremic Toxins, Oxidative Stress, and Inflammation in Hemodialysis Patients—Results of an Uncontrolled Prospective Single-Arm Study
· Medicina
Pathogenetic aspects of the development and treatment of antibiotic-associated diarrhea: the choice of a synbiotic from the standpoint of evidence-based medicine
· Meditsinskiy sovet = Medical Council
Renaissance of the vaginal microbiota: reframing clinical paradigms
· Russian Journal of Woman and Child Health
Effect of thermal treatments on the storage stability of Lactobacillus acidophilus La-14 tamarind juice with or without beta-glucans
· Malaysian Journal of Microbiology
Effect of giving probiotic supplement Lactobacillus acidophilus La-14 as an immunomodulator to maintain a respiratory system in Mus musculus
· Iranian Journal of Microbiology
Co-encapsulation of probiotic Lactobacillus acidophilus and Reishi medicinal mushroom (Ganoderma lingzhi) extract in moist calcium alginate beads
· International Journal of Biological Macromolecules
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Citations
Selected papers that name this strain.
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[1]
Source →Encapsulation of Lactobacillus acidophilus or Bifidobacterium longum Using Whey Protein Concentrate and Fructans as Wall Materials: Properties, Stability, and Viability in Simulated Gastrointestinal Tests· ACS Food Science & Technology · 2024
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[2]
Source →Viability of Lactobacillus acidophilus La-14 included in spray-dried microdiets for fish larvae· Research Square · 2023
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[3]
PMID 37629672 →The Effect of Synbiotic Supplementation on Uremic Toxins, Oxidative Stress, and Inflammation in Hemodialysis Patients—Results of an Uncontrolled Prospective Single-Arm Study· Medicina · 2023
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[4]
PMID 24471378 →In Vitro Anti‐Inflammatory Activity of Selected Oxalate‐Degrading Probiotic Bacteria: Potential Applications in the Prevention and Treatment of Hyperoxaluria· Journal of Food Science · 2014
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[5]
PMID 22143809 →Bacteriocin production and resistance to drugs are advantageous features for Lactobacillus acidophilus La-14, a potential probiotic strain.· PubMed · 2011
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[6]
PMID 18422632 →Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial· FEMS Immunology & Medical Microbiology · 2008