Strain Profile
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Lactobacillus gasseri CP2305
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus gasseri CP2305 has a substantial body of human clinical research for a single probiotic strain, with multiple randomized controlled trials and a meta-analysis in the index. This research, including studies of heat-inactivated ('paraprobiotic') forms, has examined sleep quality, self-reported stress and fatigue, and bowel regularity as outcome measures. Irritable bowel syndrome symptoms have also been examined as a research topic. Evidence is predominantly from Japanese study populations, so generalizability to other groups warrants further study, and most outcomes reflect participant-reported measures rather than disease endpoints. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 20 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 19 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
22 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
RCT
2025
REVIEW
2023
META_ANALYSIS
2022
RCT
2021
RCT
2020
ANIMAL
2019
RCT
2019
REVIEW
2019
RCT
2017
RCT
2017
RCT
2017
RCT
2017
RCT
2016
RCT
2016
RCT
2015
RCT
2009
RCT
2026
REVIEW
2025
REVIEW
2013
RCT
Browse all 22 papers →
Evaluation of the safety of high-dose Lactobacillus gasseri CP2305 supplementation in healthy adults: A randomized, double-blind, placebo-controlled study
· Toxicology Reports
Heat-inactivated Lactobacillus gasseri CP2305 improves bowel function and gut microbiota – A systematic literature review
· Clinical Nutrition Open Science
Daily consumption of Lactobacillus gasseri CP2305 improves quality of sleep in adults – A systematic literature review and meta-analysis
· Clinical Nutrition
Effects of Lactobacillus gasseri CP2305 on Mild Menopausal Symptoms in Middle-Aged Women
· Nutrients
Daily intake of Lactobacillus gasseri CP2305 ameliorates psychological premenstrual symptoms in young women: A randomized, double-blinded, placebo-controlled study
· Journal of Functional Foods
Effects of dietary intake of heat-inactivated Lactobacillus gasseri CP2305 on stress-induced behavioral and molecular changes in a subchronic and mild social defeat stress mouse model
· Biomedical Research
Daily intake of Lactobacillus gasseri CP2305 relieves fatigue and stress-related symptoms in male university Ekiden runners: A double-blind, randomized, and placebo-controlled clinical trial
· Journal of Functional Foods
The effects of viable and non-viable Lactobacillus gasseri CP2305 cells on colonic ion transport and corticotropin releasing factor-induced diarrhea
· Biomedical Research
Health Benefits of Lactobacillus gasseri CP2305 Tablets in Young Adults Exposed to Chronic Stress: A Randomized, Double-Blind, Placebo-Controlled Study
· Nutrients
Para‐psychobiotic Lactobacillus gasseri CP 2305 ameliorates stress‐related symptoms and sleep quality
· Journal of Applied Microbiology
Daily administration of paraprobiotic Lactobacillus gasseri CP2305 ameliorates chronic stress-associated symptoms in Japanese medical students
· Journal of Functional Foods
Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course
· Journal of Functional Foods
Para-psychobiotic Lactobacillus gasseri CP2305 ameliorates stress-related symptoms and sleep quality
· Institutional Repositories DataBase (IRDB)
Regulatory effect of paraprobiotic Lactobacillus gasseri CP2305 on gut environment and function
· Microbial Ecology in Health and Disease
The effects of administration of the Lactobacillus gasseri strain CP2305 on quality of life, clinical symptoms and changes in gene expression in patients with irritable bowel syndrome
· Journal of Applied Microbiology
Effect of continuous ingestion of a beverage prepared with Lactobacillus gasseri CP2305 inactivated by heat treatment on the regulation of intestinal function
· Food Research International
Stress-Relieving Effects of Lactobacillus gasseri CP2305
Lactobacillus gasseri CP2305株のストレス緩和作用
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Postbiotics in Functional Foods: Preparation-Based Characterization, Gut–Brain Axis Interactions, and Translational Perspectives
· Foods
Transforming mental health: the future of personalized psychobiotics in anxiety and depression therapy
· Frontiers in Neuroscience
Changes in Gene Expression of Peripheral Blood Leukocytes in IBS Patients Following Administration of Lactobacillus gasseri CP2305
Lactobacillus gasseri CP2305株の投与によるIBS患者末梢血白血球の遺伝子発現変化
· ストレス科学
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Citations
Selected papers that name this strain.
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[1]
Source →Heat-inactivated Lactobacillus gasseri CP2305 improves bowel function and gut microbiota – A systematic literature review· Clinical Nutrition Open Science · 2025
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[2]
PMID 37413809 →Daily consumption of Lactobacillus gasseri CP2305 improves quality of sleep in adults – A systematic literature review and meta-analysis· Clinical Nutrition · 2023
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[3]
PMID 35565662 →Effects of Lactobacillus gasseri CP2305 on Mild Menopausal Symptoms in Middle-Aged Women· Nutrients · 2022
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[4]
Source →Daily intake of Lactobacillus gasseri CP2305 ameliorates psychological premenstrual symptoms in young women: A randomized, double-blinded, placebo-controlled study· Journal of Functional Foods · 2021
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[5]
Source →Daily intake of Lactobacillus gasseri CP2305 relieves fatigue and stress-related symptoms in male university Ekiden runners: A double-blind, randomized, and placebo-controlled clinical trial· Journal of Functional Foods · 2019
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[6]
PMID 31405122 →Health Benefits of Lactobacillus gasseri CP2305 Tablets in Young Adults Exposed to Chronic Stress: A Randomized, Double-Blind, Placebo-Controlled Study· Nutrients · 2019
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[7]
Source →Daily administration of paraprobiotic Lactobacillus gasseri CP2305 ameliorates chronic stress-associated symptoms in Japanese medical students· Journal of Functional Foods · 2017
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[8]
Source →Daily intake of Lactobacillus gasseri CP2305 improves mental, physical, and sleep quality among Japanese medical students enrolled in a cadaver dissection course· Journal of Functional Foods · 2017
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[9]
PMID 27761980 →The effects of administration of the Lactobacillus gasseri strain CP2305 on quality of life, clinical symptoms and changes in gene expression in patients with irritable bowel syndrome· Journal of Applied Microbiology · 2016
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[10]
Source →Effect of continuous ingestion of a beverage prepared with Lactobacillus gasseri CP2305 inactivated by heat treatment on the regulation of intestinal function· Food Research International · 2015