Strain Profile
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Lactobacillus helveticus MIMLh5
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus helveticus MIMLh5 is a respiratory-tract probiotic strain studied for its interaction with the pharyngeal mucosa, the tissue lining the throat and tonsils. In vitro research has examined its surface layer protein (S-layer) in relation to uptake by dendritic cells, the sentinels of the innate immune system, and cytokine responses. Observational and in vitro studies have examined adhesion of Group A Streptococcus to pharyngeal epithelium and the frequency of nose and throat infections in children, though randomized controlled trial evidence is limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 14 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 3 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
15 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2025
WGS
2025
IN_VITRO
2024
OBSERVATIONAL
2023
OBSERVATIONAL
2020
OBSERVATIONAL
2019
IN_VITRO
2017
IN_VITRO
2013
IN_VITRO
2013
IN_VITRO
2012
IN_VITRO
2012
IN_VITRO
2012
IN_VITRO
2010
IN_VITRO
2007
IN_VITRO
2021
ANIMAL
Browse all 15 papers →
Microbiome of the lymphatic pharyngeal ring and probiotics
· Medical alphabet
The Capacities of the Probiotic Strains L. helveticus MIMLh5 and L. acidophilus NCFM to Induce Th1-Stimulating Cytokines in Dendritic Cells Are Inversely Correlated with the Thickness of Their S-Layers
· Biomolecules
The Efficacy of Paraprobiotic Lozenges (Lactobacillus helveticus MIMLh5) for the Prevention of Acute and Chronic Nose and Throat Infections in Children
· Medicina
EFFICACY OF A NATURAL COMPLEX WITH RESPIRATORY PROBIOTIC LACTOBACILLUS HELVETICUS MIMLH5 AND HYALURONIC ACID IN CHRONIC PHARYNGITIS AND CHRONIC TONSILLITIS
· OTORHINOLARYNGOLOGY
Effects of paraprobiotic MIMLh5 in the treatment of chronic rhinopharyngitis
· Otorinolaringologia
Surface Layer of Lactobacillus helveticus MIMLh5 Promotes Endocytosis by Dendritic Cells
· Applied and Environmental Microbiology
In vitro assessment of the ability of probiotics, blueberry and food carbohydrates to prevent S. pyogenes adhesion on pharyngeal epithelium and modulate immune responses
· Food & Function
Lactobacillus helveticus MIMLh5-Specific Antibodies for Detection of S-Layer Protein in Grana Padano Protected-Designation-of-Origin Cheese
· Applied and Environmental Microbiology
MODULATION OF HOST INNATE IMMUNITY BY HEALTH-PROMOTING BACTERIA AND DIETARY COMPOUNDS
· Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)
S-Layer Protein Mediates the Stimulatory Effect of Lactobacillus helveticus MIMLh5 on Innate Immunity
· Applied and Environmental Microbiology
In Vitro Functional and Immunomodulatory Properties of the Lactobacillus helveticus MIMLh5-Streptococcus salivarius ST3 Association That Are Relevant to the Development of a Pharyngeal Probiotic Product
· Applied and Environmental Microbiology
BIOACTIVES IN MILK-DERIVED PRODUCTS: BACTERIAL PRODUCTION OF IMMUNOMODULATORY CASEIN HYDROLYSATES AND TOOLS FOR IDENTIFICATION OF IMMUNOGENIC BACTERIAL PROTEIN
· Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)
A Dairy Bacterium Displays In Vitro Probiotic Properties for the Pharyngeal Mucosa by Antagonizing Group A Streptococci and Modulating the Immune Response
· Infection and Immunity
Bacterial Cinnamoyl Esterase Activity Screening for the Production of a Novel Functional Food Product
· Applied and Environmental Microbiology
Probiotics Modulate Mouse Gut Microbiota and Influence Intestinal Immune and Serotonergic Gene Expression in a Site-Specific Fashion
· Frontiers in Microbiology
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 39202516 →The Efficacy of Paraprobiotic Lozenges (Lactobacillus helveticus MIMLh5) for the Prevention of Acute and Chronic Nose and Throat Infections in Children· Medicina · 2024
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[2]
PMID 23220964 →S-Layer Protein Mediates the Stimulatory Effect of Lactobacillus helveticus MIMLh5 on Innate Immunity· Applied and Environmental Microbiology · 2012
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[3]
PMID 22504812 →In Vitro Functional and Immunomodulatory Properties of the Lactobacillus helveticus MIMLh5-Streptococcus salivarius ST3 Association That Are Relevant to the Development of a Pharyngeal Probiotic Product· Applied and Environmental Microbiology · 2012
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[4]
Source →BIOACTIVES IN MILK-DERIVED PRODUCTS: BACTERIAL PRODUCTION OF IMMUNOMODULATORY CASEIN HYDROLYSATES AND TOOLS FOR IDENTIFICATION OF IMMUNOGENIC BACTERIAL PROTEIN· Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · 2012