Lactobacillus johnsonii NCC533
Lactobacillus johnsonii NCC533 (also designated La1) is a well-characterized intestinal strain whose genome and secretome have been studied extensively. Animal model research has examined immune balance, including Th1/Th2 responses, and studies in mice with NC/Nga genetics, a model for atopic dermatitis, have examined early-life administration in relation to allergic skin responses. In vitro work has characterized surface proteins involved in intestinal adhesion, including a cell-surface elongation factor Tu documented to mediate attachment to human intestinal cells and mucins in laboratory studies. Human evidence for NCC533 is limited to genome and secretome characterization; findings from rodent allergy models and a separate canine microbiota study have not been evaluated in controlled human trials. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 11 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 3 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
21 papers reference this strain in the probiotic database.
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