Strain Profile
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Lactobacillus johnsonii
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus johnsonii is a facultative anaerobic lactic acid bacterium originally isolated from the human vaginal microbiota. Research has examined its role in probiotic applications across in vitro fermentation, adhesion assays, and animal models, including studies of gut microbial composition and intestinal health markers in canine and rodent systems. Select strains have been investigated for functional properties, including interactions with pathogenic bacterial adhesion and immune response markers, in cell culture systems. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 762 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 216 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+16 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
1396 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
OTHER
2026
OTHER
2026
ANIMAL
2026
WGS
2026
IN_VITRO
2026
OTHER
2026
ANIMAL
2026
ANIMAL
2026
WGS
2026
ANIMAL
2026
ANIMAL
2026
IN_VITRO
2026
IN_VITRO
2026
IN_VITRO
2026
ANIMAL
2026
OTHER
2026
OTHER
2026
OTHER
2026
OTHER
2026
ANIMAL
Browse all 1,396 papers →
Modulation of Bone Marrow-Derived Dendritic Cells by Lactobacillus johnsonii in Mice Carrying a Null Mutation in the Muc2 Gene
МОДУЛЯЦИЯ LACTOBACILLUS JOHNSONII ДЕНДРИТНЫХ КЛЕТОК КОСТНО-МОЗГОВОГО ПРОИСХОЖДЕНИЯ У МЫШЕЙ, НЕСУЩИХ НУЛЕВУЮ МУТАЦИЮ В ГЕНЕ MUC2
· CyberLeninK (CyberLeninka)
Sa1716 LACTOBACILLUS JOHNSONII AS A KEY FUNCTIONAL BACTERIUM MEDIATING THE THERAPEUTIC EFFECTS OF BANXIA XIEXIN DECOCTION IN FUNCTIONAL DYSPEPSIA
· Gastroenterology
Targeted lung Lactobacillus johnsonii intervention alleviates virus-induced fibrosis post-HCT through PD-L1/PD-1 signaling
· Science Advances
Impact of Lactobacillus johnsonii on glycemic control and lipid metabolism in type 2 diabetes with circadian disruption
· Scientific Reports
Secretome-Mediated Antimicrobial and Immunomodulatory Activity of Lactobacillus johnsonii Against Multidrug-Resistant Enteroaggregative Escherichia coli
· Zenodo (CERN European Organization for Nuclear Research)
Lactobacillus johnsonii DM2420 Alleviates Dyslipidemia, Remodels Gut Microbiota, and Modulates the Intestinal CD36/SREBP1 Signaling Axis
· Probiotics and Antimicrobial Proteins
Intratumoral Lactobacillus johnsonii Enhances Sensitivity to PD-1 Blockade by Inducing CD8+ T-cell Expansion in Hepatocellular Carcinoma
· Cancer Research
Regulation effect of Lactobacillus johnsonii on chickens infected with Ascaridia galli
· Poultry Science
Improvement of Insulin Resistance by Lactobacillus johnsonii-Derived Indole-3-Lactic Acid
· Microorganisms
Correction: Role of Lactobacillus Johnsonii in Gastroesophageal Reflux Disease in Obese Mice Following Sleeve Gastrectomy
· Obesity Surgery
Lactobacillus johnsonii ameliorates CUMS-induced depressive-like behaviors by modulating tryptophan metabolism and intestinal barrier function
· Food Bioscience
Diet-microbiota-metabolite interactions in animal health: insights from Lactobacillus johnsonii-FM1 and vanillic acid
· Frontiers in Veterinary Science
Host HSP90AA1 Contributes to Lactobacillus Johnsonii Adhesion and Reduced Pathogen Adhesion in Bovine Vaginal Epithelial Cells
· Probiotics and Antimicrobial Proteins
Two Bile Salt Hydrolase Homologues Drive Bile Resistance in Lactobacillus johnsonii ATCC 43121
· Journal of Agricultural and Food Chemistry
LACTOBACILLUS JOHNSONII ON GROWTH PERFORMANCE AND LIPID METABOLISM IN MONOPTERUS ALBUS
· Acta Hydrobiologica Sinica
Probiotic Lactobacillus johnsonii RS-7 Alleviates Intestinal Inflammation Via the TLR4/MyD88/NF-κB Signaling Pathway
· Probiotics and Antimicrobial Proteins
Lactobacillus johnsonii
· BacDive
Lactobacillus johnsonii Fujisawa et al. 1992
· BacDive
Identification and catalytic characterization of a thermostable PET-hydrolyzing enzyme from Lactobacillus johnsonii
· Molecular Catalysis
Lactobacillus johnsonii and 3-indolepropionic acid improve the depression-like behaviors via inhibiting neuroinflammation
· Pharmacological Research
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →Identification and catalytic characterization of a thermostable PET-hydrolyzing enzyme from Lactobacillus johnsonii· Molecular Catalysis · 2026
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[2]
PMID 41683964 →The Role of Probiotics Limosilactobacillus reuteri, Ligilactobacillus salivarius, and Lactobacillus johnsonii in Inhibziting Pathogens, Maintaining Gut Health, and Improving Disease Outcomes· International Journal of Molecular Sciences · 2026
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[3]
PMID 40565640 →In Situ Cross-Linked Porous Starch Microencapsulation Enhances the Colonization of Lactobacillus In Vivo· Foods · 2025
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[4]
PMID 40822402 →Unveiling the potential of Lactobacillus johnsonii in digestive diseases: a comprehensive review· Frontiers in Microbiology · 2025
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[5]
PMID 38674920 →Beneficial Effect of Heat-Killed Lactic Acid Bacterium Lactobacillus johnsonii No. 1088 on Temporal Gastroesophageal Reflux-Related Symptoms in Healthy Volunteers: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study· Nutrients · 2024
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[6]
PMID 38778442 →Modulating commensal bacteria to intervene in cancer immunotherapy· Clinical and Translational Medicine · 2024
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[7]
Source →Kết quả ban đầu sử dụng kháng thể IgY và Lactobacillus johnsonii trong hỗ trợ diệt trừ Helicobacter pylori· Tạp chí Nghiên cứu Y học · 2022
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[8]
Source →Synbiotic Supplementation Facilitates Weight Loss, Improves Lipid Profile and Gut Health in Overweight and Obese Subjects· International Journal of Probiotics and Prebiotics · 2022
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[9]
Source →The Suppressive Effect of Supplementation of Combined Probiotic on Helicobacter pylori Infection· Current Developments in Nutrition · 2020
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[10]
PMID 28721083 →Effect of a lotion containing the heat-treated probiotic strain Lactobacillus johnsonii NCC 533 on Staphylococcus aureus colonization in atopic dermatitis· Clinical Cosmetic and Investigational Dermatology · 2017