Strain Profile
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Streptococcus pneumoniae

◔ Human-origin
Sequenced
Public genome assembly available

Streptococcus pneumoniae (the pneumococcus) is a commensal bacterium of the upper respiratory tract that can cause serious opportunistic infections — including pneumonia, meningitis, and septicemia — particularly in immunocompromised individuals, young children, and older adults; it is not a probiotic organism. The indexed research for this entry covers antibiotic resistance, virulence mechanisms, serotyping, and vaccine development, none of which reflects probiotic utility. This strain is included in the catalog for reference purposes, likely due to its appearance in microbiome research contexts, but should not be construed as having probiotic applications.

Where it's been studied

Share of this strain's 243 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+1 more systems

Symptoms in the research

Share of this strain's 35 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

435 papers reference this strain in the probiotic database.

Match confidence
2024 REVIEW
Streptococcus pneumoniae epidemiology, pathogenesis and control
· Nature Reviews Microbiology
2020 OBSERVATIONAL
High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi
· Nature Communications
2020 REVIEW
Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection
· Vaccines
2019 REVIEW
Streptococcus pneumoniae: Invasion and Inflammation
· Microbiology Spectrum
2019 REVIEW
Mechanisms of Naturally Acquired Immunity to Streptococcus pneumoniae
· Frontiers in Immunology
2019 REVIEW
Emerging concepts in the pathogenesis of the Streptococcus pneumoniae: From nasopharyngeal colonizer to intracellular pathogen
· Cellular Microbiology
2019 REVIEW
Competence in Streptococcus pneumoniae and Close Commensal Relatives: Mechanisms and Implications
· Frontiers in Cellular and Infection Microbiology
2018 WGS
SeroBA: rapid high-throughput serotyping of Streptococcus pneumoniae from whole genome sequence data
· Microbial Genomics
2018 OBSERVATIONAL
Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000–15
· The Lancet Global Health
2018 OTHER
Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39
· Nucleic Acids Research
2017 REVIEW
Quorum Sensing Regulation of Competence and Bacteriocins in Streptococcus pneumoniae and mutans
· Genes
2017 REVIEW
Role of Streptococcus pneumoniae Proteins in Evasion of Complement-Mediated Immunity
· Frontiers in Microbiology
2017 IN_VITRO
High‐throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae
· Molecular Systems Biology
2017 REVIEW
Streptococcus pneumoniae serotype 19A: worldwide epidemiology
· Expert Review of Vaccines
2017 REVIEW
Antimicrobial Resistant Streptococcus pneumoniae: Prevalence, Mechanisms, and Clinical Implications
· American Journal of Therapeutics
2017 OTHER
A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine
· Science Translational Medicine
2016 WGS
Penicillin-Binding Protein Transpeptidase Signatures for Tracking and Predicting β-Lactam Resistance Levels in Streptococcus pneumoniae
· mBio
2016 REVIEW
Macrolide Resistance in Streptococcus pneumoniae
· Frontiers in Cellular and Infection Microbiology
2016 REVIEW
Nonencapsulated Streptococcus pneumoniae: Emergence and Pathogenesis
· mBio
2016 ANIMAL
Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model
· Journal of Neuroinflammation
Browse all 435 papers →

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