Strain Profile
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Streptococcus mitis

◔ Human-origin
Sequenced
Public genome assembly available

Streptococcus mitis is a gram-positive commensal bacterium that forms part of the normal oral and upper respiratory microbiota in humans. It is closely related to Streptococcus pneumoniae and shares genomic features that have been studied to understand pathogen evolution; research documents instances of S. mitis causing opportunistic infections such as endocarditis and meningitis in immunocompromised individuals. It is not classified as a probiotic organism. The available indexed literature focuses on its taxonomy, phylogenetics, antimicrobial susceptibility, and its role as a commensal that can occasionally shift to pathogenic behavior; it is included here in a research and taxonomic context only. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 224 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+4 more systems

Symptoms in the research

Share of this strain's 167 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

367 papers reference this strain in the probiotic database.

Match confidence
2025 WGS
Re-evaluation of boundaries of Streptococcus mitis and Streptococcus oralis and demonstration of multiple later synonyms of Streptococcus mitis, Streptococcus oralis and Streptococcus thalassemiae: description of Streptococcus mitis subsp. carlssonii subsp. nov. and emended description of Streptococcus mitis
· INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
2024 OTHER
Oral streptococci S. anginosus and S. mitis induce distinct morphological, inflammatory, and metabolic signatures in macrophages
· Infection and Immunity
2024 WGS
Population genomics of Streptococcus mitis in UK and Ireland bloodstream infection and infective endocarditis cases
· Nature Communications
2023 IN_VITRO
Developing multispecies quorum-sensing modulators based on the Streptococcus mitis competence-stimulating peptide
· Journal of Biological Chemistry
2023 REVIEW
Streptococcus mitis as a New Emerging Pathogen in Pediatric Age: Case Report and Systematic Review
· Antibiotics
2023 OBSERVATIONAL
A Case of Urinary Tract Infection Caused by Multidrug Resistant Streptococcus mitis/oralis
· Infection and Drug Resistance
2022 WGS
DNA isolation methods for Nanopore sequencing of the Streptococcus mitis genome
· Microbial Genomics
2022 IN_VITRO
Commensal Bacteria in the Cystic Fibrosis Airway Microbiome Reduce P. aeruginosa Induced Inflammation
· Frontiers in Cellular and Infection Microbiology
2022 WGS
Novel Multilocus Sequence Typing and Global Sequence Clustering Schemes for Characterizing the Population Diversity of Streptococcus mitis
· Journal of Clinical Microbiology
2021 WGS
Streptococcus pneumoniae serotypes that frequently colonise the human nasopharynx are common recipients of penicillin-binding protein gene fragments from Streptococcus mitis
· Microbial Genomics
2021 IN_VITRO
The c‐di‐AMP signaling system influences stress tolerance and biofilm formation of Streptococcus mitis
· MicrobiologyOpen
2021 IN_VITRO
Streptococcus pneumoniae, S. mitis, and S. oralis Produce a Phosphatidylglycerol-Dependent, ltaS-Independent Glycerophosphate-Linked Glycolipid
· mSphere
2021 OTHER
Commensal Streptococcus mitis produces two different lipoteichoic acids of type I and type IV
· Glycobiology
2021 OBSERVATIONAL
Genomic relatedness and clinical significance of Streptococcus mitis strains isolated from the urogenital tract of sexual partners
· Microbial Genomics
2021 OTHER
A case report of streptococcal toxic shock syndrome caused by Streptococcus mitis in a healthy adult
· BMC Infectious Diseases
2020 IN_VITRO
Differential influence of Streptococcus mitis on host response to metals in reconstructed human skin and oral mucosa
· Contact Dermatitis
2020 IN_VITRO
Cyclic Di-adenosine Monophosphate Regulates Metabolism and Growth in the Oral Commensal Streptococcus mitis
· Microorganisms
2020 IN_VITRO
Rapid and Accurate Species Identification of Mitis Group Streptococci Using the MinION Nanopore Sequencer
· Frontiers in Cellular and Infection Microbiology
2019 IN_VITRO
PcsB Expression Diversity Influences on Streptococcus mitis Phenotypes Associated With Host Persistence and Virulence
· Frontiers in Microbiology
2019 ANIMAL
Intranasal Immunization with the Commensal Streptococcus mitis Confers Protective Immunity against Pneumococcal Lung Infection
· Applied and Environmental Microbiology
Browse all 367 papers →

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