Strain Profile
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Bifidobacterium lactis V9

◔ Human-origin
Sequenced
Public genome assembly available

Bifidobacterium lactis V9 is a probiotic strain developed in China (Inner Mongolia) that has been studied for its survival characteristics and potential interactions with gut microbiota. Observational research has examined gut microbial composition and, in one small study, hormonal parameters in women with polycystic ovary syndrome (PCOS); these findings are preliminary and not conclusive. Animal studies have explored non-alcoholic fatty liver and colitis models, and a 2025 RCT examined its use as an adjunct in colorectal cancer patients. Most of this evidence is early-stage and strain-specific human efficacy data remain limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 9 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Research

27 papers reference this strain in the probiotic database.

Match confidence
2026 ANIMAL
Synergistic antitumor and immunomodulatory effects of Bifidobacterium animalis subsp. lactis V9 combined with anti–PD-1 therapy
· Frontiers in Immunology
2026 RCT
Bifidobacterium animalis subsp. lactis V9 overcomes CYFRA 21-1–linked immunochemotherapy resistance in NSCLC via microbial metabolites
· Science Advances
2025 ANIMAL
Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice
· Frontiers in Medicine
2025 RCT
Study on the Improvement of Inflammatory Response in Colorectal Cancer Patients by Treatment Regimen Involving Bifidobacterium lactis V9
· Journal of Clinical Personalized Medicine
2020 ANIMAL
Probiotic Bifidobacterium lactis V9 attenuates hepatic steatosis and inflammation in rats with non-alcoholic fatty liver disease
· AMB Express
2020 OBSERVATIONAL
Differential pattern of indigenous microbiome responses to probiotic Bifidobacterium lactis V9 consumption across subjects
· Food Research International
2019 OBSERVATIONAL
Probiotic Bifidobacterium lactis V9 Regulates the Secretion of Sex Hormones in Polycystic Ovary Syndrome Patients through the Gut-Brain Axis
· mSystems
2012 IN_VITRO
Effects of air condition on the viability of probiotic bacteria:Bifidobacterium lactis V9
· Microbiology, China
2012 IN_VITRO
Studies on the storage stability of Bifidobacterium lactis V9 in skim milk powder
· Zhongguo rupin gongye
2012 IN_VITRO
Effects of Different Gas Atmospheres on the Growth of Probiotic Bifidobacterium lactis V9
不同气体环境对益生菌Bifidobacterium lactis V9生长的影响
· 微生物学通报
2012 IN_VITRO
Effects of Inoculation Ratio of Probiotics Lactobacillus casei Zhang and Bifidobacterium lactis V9 and Milk Solids Content on Viable Cell Counts
益生菌Lactobacillus casei Zhang和Bifidobacterium lactis V9接种比例及乳固形物含量对其活菌数的影响
· 中国乳品工业
2012 IN_VITRO
Effects of inoculum ratios of Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus on the quality of probiotic fermented milk by Bifidobacterium lactis
· Zhongguo rupin gongye
2012 IN_VITRO
Effect of Inoculation Ratio of Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus on the Quality of Bifidobacterium lactis Probiotic Fermented Dairy Products
Lactobacillus delbrueckiisubsp.bulgaricus和Streptococcus thermophilus接种比例对Bifidobacterium lactis益生菌发酵乳品质的影响
· 中国乳品工业
2011 IN_VITRO
Detection of Lactobacillus casei Zhang and Bifidobacterium lactis V9 in Probiotic Beverages by Fluorescence Quantitative PCR
荧光定量PCR法检测益生菌饮料中Lactobacillus casei Zhang和Bifidobacterium lactis V9
· 中国乳品工业
2011 IN_VITRO
Lactobacillus casei Zhang Bifidobacterium lactis V9 Method of fluorescent quantitative PCR for detection of Lactobacillus casei Zhang and Bifidobacterium lactis V9
· Zhongguo rupin gongye
2024 IN_VITRO
Untargeted metabolic footprinting uncovers key biochemical changes in fermented camel milk
· LWT
2022 ANIMAL
Immunomodulatory Effect of Triple Probiotics and Fructo-Oligosaccharide Compound Powder in Mice
· DOAJ (DOAJ: Directory of Open Access Journals)
2021 IN_VITRO
Comparative effects of the single and binary probiotics of Lacticaseibacillus casei Zhang and Bifidobacterium lactis V9 on the growth and metabolomic profiles in yogurts
· Food Research International
2021 IN_VITRO
Different growth behaviors and metabolomic profiles in yogurts induced by multistrain probiotics of Lactobacillus casei Zhang and Bifidobacterium lactis V9 under different fermentation temperatures
· Journal of Dairy Science
2021 IN_VITRO
Different growth behaviors and metabolomic profiles in yogurts induced by multi-strain probiotics of Lactobacillus casei Zhang and Bifidobacterium lactis V9 under different fermentation temperatures
· Figshare
Browse all 27 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Bifidobacterium animalis subsp. lactis V9 overcomes CYFRA 21-1–linked immunochemotherapy resistance in NSCLC via microbial metabolites
    · Science Advances · 2026
    PMID 42685222 →
  2. [2]
    Study on the Improvement of Inflammatory Response in Colorectal Cancer Patients by Treatment Regimen Involving Bifidobacterium lactis V9
    · Journal of Clinical Personalized Medicine · 2025
    Source →