Strain Profile
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Bifidobacterium lactis Probio-M8
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Bifidobacterium animalis subsp. lactis Probio-M8 is a research strain originally isolated from human colostrum and has been studied via genomic analysis for host-adaptive evolution, including the lactation route into infant gut. In vitro characterization has examined fermentation properties and organic acid production in dairy matrices. Animal model studies have examined metabolic markers, gut microbiota composition, and behavior in autism-model mice, and a 2025 human RCT examined its use alongside chondroitin in the context of knee osteoarthritis. Evidence is predominantly preclinical or early-stage. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 21 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+2 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 6 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+2 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
30 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
ANIMAL
2025
RCT
2024
IN_VITRO
2024
OBSERVATIONAL
2024
ANIMAL
2024
RCT
2024
IN_VITRO
2024
RCT
2024
RCT
2024
ANIMAL
2023
ANIMAL
2023
IN_VITRO
2022
RCT
2022
ANIMAL
2022
ANIMAL
2022
IN_VITRO
2022
IN_VITRO
2022
OBSERVATIONAL
2022
RCT
2022
IN_VITRO
Browse all 30 papers →
Maternal Probiotic Supplementation During Lactation Shapes Gut Microbiota and Metabolome in Dams and Offspring: A Multi-Omics Mouse Study
· Food Science and Human Wellness
Bifidobacterium animalis subsp. lactis Probio-M8 enhances chondroitin efficacy for knee osteoarthritis in postmenopausal women via the gut-joint axis
· mSystems
Co-culturing Bifidobacterium animalis ssp. lactis with Lactobacillus helveticus accelerates its growth and fermentation in milk through metabolic interactions
· Journal of Dairy Science
Omic characterizing and targeting gut dysbiosis in children with autism spectrum disorder: symptom alleviation through combined probiotic and medium-carbohydrate diet intervention - a pilot study
· Gut Microbes
Preventive effects of Bifidobacterium lactis Probio-M8 on ovalbumin-induced food allergy in mice
· Food Science and Human Wellness
Bifidobacterium lactis Probio-M8 relieved acute respiratory tract infections in children possibly by modulating the gut microbes and metabolites
· Journal of Functional Foods
Probiotic Bifidobacterium animalis ssp. lactis Probio-M8 improves the fermentation and probiotic properties of fermented milk
· Journal of Dairy Science
Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites
· npj Biofilms and Microbiomes
Short‐term probiotic supplementation affects the diversity, genetics, growth, and interactions of the native gut microbiome
· iMeta
Bifidobacterium lactis Probio‐M8 prevents nonalcoholic fatty liver disease in high‐fat diet‐fed rats: The potential role in modulating gut microbiota
· Food Bioengineering
Bifidobacterium animalis subsp. lactis Probio-M8 alleviates abnormal behavior and regulates gut microbiota in a mouse model suffering from autism
· mSystems
Metabolic dynamics of fermented milk beverages co-fermented with Bifidobacterium animalis subsp. lactis Probio-M8 and Lacticaseibacillus paracasei PC-01 during storage
· LWT
Bifidobacterium lactis Probio-M8 Adjuvant Treatment Confers Added Benefits to Patients with Coronary Artery Disease via Target Modulation of the Gut-Heart/-Brain Axes
· mSystems
Intake of Bifidobacterium lactis Probio-M8 fermented milk protects against alcoholic liver disease
· Journal of Dairy Science
Bifidobacterium lactis Probio-M8 ameliorated the symptoms of type 2 diabetes mellitus mice by changing ileum FXR-CYP7A1
· Open Medicine
Protective effects of whey protein hydrolysate on Bifidobacterium animalis ssp. lactis Probio-M8 during freeze-drying and storage
· Journal of Dairy Science
Probiotic Bifidobacterium animalis ssp. lactis Probio-M8 improves the properties and organic acid metabolism of fermented goat milk
· Journal of Dairy Science
Bifidobacterium animalis subsp. lactis Probio-M8 undergoes host adaptive evolution by glcU mutation and translocates to the infant’s gut via oral-/entero-mammary routes through lactation
· Microbiome
Probiotics synergized with conventional regimen in managing Parkinson’s disease
· npj Parkinson s Disease
Probiotic Bifidobacterium animalis ssp. lactis Probio-M8 improves the properties and organic acid metabolism of fermented goats’ milk
· Figshare
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Citations
Selected papers that name this strain.
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[1]
PMID 41313018 →Bifidobacterium animalis subsp. lactis Probio-M8 enhances chondroitin efficacy for knee osteoarthritis in postmenopausal women via the gut-joint axis· mSystems · 2025
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[2]
PMID 39632843 →Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites· npj Biofilms and Microbiomes · 2024
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[3]
PMID 36419187 →Bifidobacterium animalis subsp. lactis Probio-M8 undergoes host adaptive evolution by glcU mutation and translocates to the infant’s gut via oral-/entero-mammary routes through lactation· Microbiome · 2022
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[4]
PMID 35610236 →Probiotics synergized with conventional regimen in managing Parkinson’s disease· npj Parkinson s Disease · 2022