Clostridium tyrobutyricum
Clostridium tyrobutyricum is an anaerobic, spore-forming bacterium studied primarily for its industrial fermentation properties, specifically its high-yield production of butyric acid from sugars, which has made it a subject of metabolic engineering research for bio-based chemical production. It is also recognized as a spoilage organism in silage and dairy products, and occurs naturally in cattle feed. C. tyrobutyricum is not a recognized probiotic organism; the available research reflects industrial biotechnology and food safety contexts. Butyrate, the salt of butyric acid, is a short-chain fatty acid studied in relation to gut epithelial health, but the organism itself is not characterized for safe human administration, and no probiotic safety or efficacy data were identified in the indexed literature. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 66 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+3 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 16 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
440 papers reference this strain in the probiotic database.
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Citations
Selected papers that name this strain.
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[1]
PMID 38816643 →Microbiome dysbiosis in patients with chronic endometritis and Clostridium tyrobutyricum ameliorates chronic endometritis in mice· Scientific Reports · 2024
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[2]
PMID 39099138 →Clostridium tyrobutyricum in Combination with Chito-oligosaccharides Modulate Inflammation and Gut Microbiota for Inflammatory Bowel Disease Treatment· Journal of Agricultural and Food Chemistry · 2024
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[3]
Source →DataSheet_1_A Potential Probiotic for Diarrhea: Clostridium tyrobutyricum Protects Against LPS-Induced Epithelial Dysfunction via IL-22 Produced By Th17 Cells in the Ileum.xlsx· Figshare · 2021
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[4]
Source →DataSheet_2_A Potential Probiotic for Diarrhea: Clostridium tyrobutyricum Protects Against LPS-Induced Epithelial Dysfunction via IL-22 Produced By Th17 Cells in the Ileum.pdf· Figshare · 2021
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[5]
PMID 25118984 →The Gut Microbiota and Developmental Programming of the Testis in Mice· PLoS ONE · 2014