Lactococcus lactis W58
Lactococcus lactis W58 appears primarily in multi-strain probiotic supplement studies rather than as a solo intervention, making it difficult to attribute outcomes to this strain specifically. Several RCTs using 7- to 9-strain blends containing W58 have examined cardiometabolic markers and endotoxin levels in type 2 diabetes patients, postmenopausal women with obesity, infants at risk for eczema, and athletes during intense training periods. In vitro work using batch fermentation models has examined gut metabolite production, including short-chain fatty acids and tryptophan metabolites, in W58-containing blends. Strain-specific mechanistic evidence is sparse, and W58 appears primarily as a component of multi-strain formulations rather than a stand-alone characterized probiotic. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 14 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+2 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 7 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
17 papers reference this strain in the probiotic database.
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Citations
Selected papers that name this strain.
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[1]
PMID 40646644 →Network meta-analysis of randomized control trials evaluating the effectiveness of various probiotic formulations in patients with type 2 diabetes mellitus· Diabetology & Metabolic Syndrome · 2025
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[2]
PMID 41068905 →12-week preoperative probiotic supplementation versus placebo: effects on inflammation, endotoxemia, adipokines, and gastrointestinal peptides in patients six months after bariatric surgery – a double-blind, randomized, placebo-controlled clinical trial· Nutrition Journal · 2025
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[3]
PMID 29228964 →Effects of a multi-strain probiotic supplement for 12 weeks in circulating endotoxin levels and cardiometabolic profiles of medication naïve T2DM patients: a randomized clinical trial· Journal of Translational Medicine · 2017
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[4]
Source →Daily intake of a 7-strain probiotic supplement for 12 weeks improves cardiometabolic profiles of naïve T2DM patients· · 2017