Strain Profile
· NCBI Strain Taxon
1001583
NCBI Taxonomy's node for this specific strain. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
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Levilactobacillus brevis KB290
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
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Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
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Public genome assembly available
Levilactobacillus brevis KB290 (formerly Lactobacillus brevis KB290) is a Japanese probiotic strain with a sequenced genome and a body of human and animal research. Two randomized controlled trials examined this strain in the context of irritable bowel syndrome, including diarrhea-predominant IBS in combination with beta-carotene, and an open-label pilot study examined influenza incidence among schoolchildren who consumed it. Animal research has examined its cell-bound exopolysaccharides — complex surface carbohydrates — in relation to immune cell activity and intestinal inflammation, and in vitro work has characterized its interaction with gut pathogens. Most human trials in the indexed literature are small or exploratory in design. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 21 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 8 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
23 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
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2021
RCT
2021
ANIMAL
2020
ANIMAL
2020
RCT
2019
WGS
2018
ANIMAL
2017
RCT
2016
ANIMAL
2014
ANIMAL
2014
IN_VITRO
2014
OBSERVATIONAL
2014
ANIMAL
2014
OBSERVATIONAL
2013
ANIMAL
2013
WGS
2013
IN_VITRO
2013
ANIMAL
2013
IN_VITRO
2012
RCT
2025
IN_VITRO
Browse all 23 papers →
Effects of Heat-Killed Levilactobacillus brevis KB290 in Combination with β-Carotene on Influenza Virus Infection in Healthy Adults: A Randomized Controlled Trial
· Nutrients
Heat‐killed Lactobacillus brevis KB290 attenuates visceral fat accumulation induced by high‐fat diet in mice
· Journal of Applied Microbiology
Short Communication: Oral Administration of Heat-killed Lactobacillus brevis KB290 in Combination with Retinoic Acid Provides Protection against Influenza Virus Infection in Mice
· Nutrients
Verification of the Efficacy of Lactobacillus brevis KB290 Intake on Skin Moisture Function in Healthy Women with Self-Reported Dry Skin: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Trial
乾燥肌を自覚する健常女性の皮膚保湿機能に対するLactobacillus brevis KB290 摂取の有効性の検証―ランダム化プラセボ対照二重盲検並行群間比較試験―
· 薬理と治療
Relation between cell‐bound exopolysaccharide production via plasmid‐encoded genes and rugose colony morphology in the probiotic Lactobacillus brevis KB290
· Animal Science Journal
Lactobacillus brevis KB290 With Vitamin A Ameliorates Murine Intestinal Inflammation Associated With the Increase of CD11c+ Macrophage/CD103− Dendritic Cell Ratio
· Inflammatory Bowel Diseases
Effect of combined consumption of Lactobacillus brevis KB290 andβ-carotene on minor diarrhoea-predominant irritable bowel syndrome-like symptoms in healthy subjects: a randomised, double-blind, placebo-controlled, parallel-group trial
· International Journal of Food Sciences and Nutrition
Amelioration of Citrobacter rodentium proliferation in early stage of infection in mice by pre-treatment with Lactobacillus brevis KB290 and verification using in vivo bioluminescence imaging
· FEMS Microbiology Letters
Cell-bound exopolysaccharides of Lactobacillus brevis KB290 enhance cytotoxic activity of mouse splenocytes
· Journal of Applied Microbiology
Growth and bile tolerance of Lactobacillus brevis strains isolated from Japanese pickles in artificial digestive juices and contribution of cell-bound exopolysaccharide to cell aggregation
· Canadian Journal of Microbiology
Effects of probiotic Lactobacillus brevis KB290 on incidence of influenza infection among schoolchildren: an open-label pilot study
· Letters in Applied Microbiology
Sequential gene expression profiling in the mouse spleen during 14 d feeding with Lactobacillus brevis KB290
· British Journal Of Nutrition
(untitled)
· Letters in Applied Microbiology
Oral administration of Lactobacillus brevis KB290 to mice alleviates clinical symptoms following influenza virus infection
· Letters in Applied Microbiology
Genomic Analysis by Deep Sequencing of the Probiotic Lactobacillus brevis KB290 Harboring Nine Plasmids Reveals Genomic Stability
· PLoS ONE
Lactobacillus brevis KB290 Enhances IL-8 Secretion by Vibrio parahaemolyticus-Infected Caco-2 Cells
· Journal of Microbiology and Biotechnology
Effect of Lactobacillus brevis KB290 on the cell-mediated cytotoxic activity of mouse splenocytes: a DNA microarray analysis
· British Journal Of Nutrition
Cell-bound exopolysaccharides of Lactobacillus brevis KB290: protective role and monosaccharide composition
· Canadian Journal of Microbiology
The effect of Lactobacillus brevis KB290 against irritable bowel syndrome: a placebo-controlled double-blind crossover trial
· BioPsychoSocial Medicine
Suppressive effects of Levilactobacillus brevis on Fusarium-plant disease and its potential contribution to environmentally friendly agriculture
· Biological Control
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 28391736 →Effect of combined consumption of Lactobacillus brevis KB290 andβ-carotene on minor diarrhoea-predominant irritable bowel syndrome-like symptoms in healthy subjects: a randomised, double-blind, placebo-controlled, parallel-group trial· International Journal of Food Sciences and Nutrition · 2017
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[2]
PMID 25294223 →Effects of probiotic Lactobacillus brevis KB290 on incidence of influenza infection among schoolchildren: an open-label pilot study· Letters in Applied Microbiology · 2014
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[3]
PMID 23544154 →Genomic Analysis by Deep Sequencing of the Probiotic Lactobacillus brevis KB290 Harboring Nine Plasmids Reveals Genomic Stability· PLoS ONE · 2013