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Weissella cibaria CMU

◐ Food-origin
Sequenced
Public genome assembly available

Weissella cibaria CMU is an oral probiotic strain (isolated from human saliva) that has been evaluated specifically in the context of oral health. Multiple human RCTs have investigated this strain in the context of halitosis (bad breath), dental caries, and gingivitis. In vitro studies have examined its interactions with oral pathogens and biofilm formation on dental and implant surfaces, and phenotypic and genomic analyses have been used to characterize the strain. W. cibaria CMU is primarily an oral microbiome intervention; any outcomes described in the literature are specific to oral health endpoints and should not be interpreted as systemic or digestive health effects. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 26 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 25 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

33 papers reference this strain in the probiotic database.

Match confidence
2026 RCT
Exploratory randomized trial of Weissella cibaria CMU and oral microbiome changes in peri implant mucositis
· Scientific Reports
2026 RCT
Oral probiotic Weissella cibaria improves halitosis and reduces periodontal pathogens: a randomized, double-blind, placebo-controlled trial
· BMC Oral Health
2026 RCT
Clinical Efficacy of the Probiotic Weissella cibaria CMU in Adults with Gingivitis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
· Journal of Medicinal Food
2024 IN_VITRO
In Vitro Effects of Weissella cibaria CMU and CMS1 on Receptor Activator of NF-κB Ligand (RANKL)-Induced Osteoclast Differentiation
· Journal of Functional Biomaterials
2023 IN_VITRO
In Vitro Preventive Effect and Mechanism of Action of Weissella cibaria CMU against Streptococcus mutans Biofilm Formation and Periodontal Pathogens
· Microorganisms
2023 RCT
Improvement of halitosis by probiotic bacterium Weissella cibaria CMU: A randomized controlled trial
· Frontiers in Microbiology
2022 ANIMAL
Toxicological and safety evaluations of Weissella cibaria strain CMU in animal toxicity and genotoxicity
· Toxicological Research
2022 ANIMAL
Therapeutic Efficacy of Weissella cibaria CMU and CMS1 on Allergic Inflammation Exacerbated by Diesel Exhaust Particulate Matter in a Murine Asthma Model
· Medicina
2021 IN_VITRO
In Vitro Evaluation of the Effect of Oral Probiotic Weissella cibaria on the Formation of Multi-Species Oral Biofilms on Dental Implant Surfaces
· Microorganisms
2021 RCT
A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Acidogenic Potential of Dental Biofilms through a Tablet Containing Weissella cibaria CMU
· International Journal of Environmental Research and Public Health
2021 IN_VITRO
Antimicrobial and Antibiofilm Activities of Weissella cibaria against Pathogens of Upper Respiratory Tract Infections
· Microorganisms
2021 RCT
Effects of Oral Probiotics on Subjective Halitosis, Oral Health, and Psychosocial Health of College Students: A Randomized, Double-Blind, Placebo-Controlled Study
· International Journal of Environmental Research and Public Health
2020 RCT
Halitosis Inhibitory Effect of Probiotic Bacterium Weissella cibaria CMU
프로바이오틱 세균인 Weissilla cibaria CMU의 구취 억제 효과
· 대한구강보건학회지
2020 ANIMAL
Effect of Weissella cibaria on the reduction of periodontal tissue destruction in mice
· Journal of Periodontology
2020 IN_VITRO
Weissella cibaria CMU exerts an anti‑inflammatory effect by inhibiting Aggregatibacter actinomycetemcomitans‑induced NF‑κB activation in macrophages
· Molecular Medicine Reports
2020 RCT
Inhibitory effect of the probiotic bacteria, Weissella cibaria CMU on halitosis: a randomized placebo-controlled study
· Journal of Korean Academy of Oral Health
2020 RCT
Effects of probiotic bacterium Weissella cibaria CMU on periodontal health and microbiota: a randomised, double-blind, placebo-controlled trial
· BMC Oral Health
2019 IN_VITRO
Safety Evaluation of Oral Care Probiotics Weissella cibaria CMU and CMS1 by Phenotypic and Genotypic Analysis
· International Journal of Molecular Sciences
2019 IN_VITRO
Weissella cibaria CMU suppresses mgl gene expression and enzyme activity associated with bad breath
· International Journal of Oral Biology
2018 IN_VITRO
Effect of Natural Extracts on Oral Care Probiotics Weissella cibaria CMU and Periodontal Pathogens
· International Journal of Oral Biology
Browse all 33 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Clinical Efficacy of the Probiotic Weissella cibaria CMU in Adults with Gingivitis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
    · Journal of Medicinal Food · 2026
    PMID 41817287 →
  2. [2]
    Antimicrobial Resistance and Transferability in Oral-Care Probiotic Strains and Products: A Narrative Review
    · Preprints.org · 2026
    Source →
  3. [3]
    Exploratory randomized trial of Weissella cibaria CMU and oral microbiome changes in peri implant mucositis
    · Scientific Reports · 2026
    PMID 41781692 →
  4. [4]
    Oral probiotic Weissella cibaria improves halitosis and reduces periodontal pathogens: a randomized, double-blind, placebo-controlled trial
    · BMC Oral Health · 2026
    PMID 41782083 →
  5. [5]
    Improvement of halitosis by probiotic bacterium Weissella cibaria CMU: A randomized controlled trial
    · Frontiers in Microbiology · 2023
    PMID 36733919 →
  6. [6]
    Toxicological and safety evaluations of Weissella cibaria strain CMU in animal toxicity and genotoxicity
    · Toxicological Research · 2022
    PMID 35865276 →
  7. [7]
    Halitosis Inhibitory Effect of Probiotic Bacterium Weissella cibaria CMU
    프로바이오틱 세균인 Weissilla cibaria CMU의 구취 억제 효과
    · 대한구강보건학회지 · 2020
    Source →
  8. [8]
    Inhibitory effect of the probiotic bacteria, Weissella cibaria CMU on halitosis: a randomized placebo-controlled study
    · Journal of Korean Academy of Oral Health · 2020
    Source →
  9. [9]
    Effects of probiotic bacterium Weissella cibaria CMU on periodontal health and microbiota: a randomised, double-blind, placebo-controlled trial
    · BMC Oral Health · 2020
    PMID 32878603 →
  10. [10]
    Clinical studies on the dental caries prevention effects of the ability of Weissella cibaria CMU to adhere to the oral cavity
    · Indian Journal of Public Health Research & Development · 2018
    Source →