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Bacteroides uniformis

◔ Human-origin
Sequenced
Public genome assembly available

Bacteroides uniformis is a common anaerobic bacterium of the human gut microbiome, and a specific strain (CECT 7771) has attracted research interest for its metabolic effects in animal models. Preclinical studies have examined B. uniformis CECT 7771 in diet-induced obesity models in mice, looking at metabolic and immune markers, including in combination with dietary fiber. The indexed data also reflect this organism's role in gut carbohydrate metabolism, particularly complex polysaccharide degradation. Strain-specific human clinical evidence is limited; B. uniformis is being studied as a next-generation probiotic candidate but has not yet established efficacy in human clinical trials. It is not currently approved or widely used as a conventional probiotic supplement. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 385 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+4 more systems

Symptoms in the research

Share of this strain's 129 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+9 more symptoms

Research

540 papers reference this strain in the probiotic database.

Match confidence
2026 ANIMAL
Bacteroides uniformis mediates the alleviative effects of Rb1 on Alcohol-associated liver disease by enhancing glutamine levels and improving the urea cycle via the GCN2-eIF2α-ATF4-SLC25A2 pathway
· Mendeley Data
2026 IN_VITRO
13C flux ratio analysis with FRAPPPE reveals differences in central carbon metabolism between gut Bacteroidota and E. coli
· Zenodo (CERN European Organization for Nuclear Research)
2026 OTHER
Consensus approach for assessing and resolving uncertainty in genome-scale metabolic models: advancing systems-level understanding of microbial metabolism
· heiDOK (Heidelberg University)
2026 ANIMAL
Distinct effects of different Bacteroides strains on depressive-like behavior via a gut-Th1/Th17 cells-brain axis
· Communications Biology
2026 ANIMAL
Gut microbiota‐mediated branched‐chain amino acid metabolism: A novel mechanism by which Bacteroides uniformis improves type 2 diabetes mellitus
· Diabetes Obesity and Metabolism
2026 ANIMAL
4-Hydroxyphenanthrene exacerbates obesity by altering gut microbiota and bile acid metabolism
· Nature Communications
2026 IN_VITRO
13 C flux ratio analysis with FRAPPPE reveals differences in metabolic fluxes between gut Bacteroidota and Escherichia coli
· bioRxiv (Cold Spring Harbor Laboratory)
2026 ANIMAL
Tryptophan degradation by intestinal Bacteroides induces anti-tumor immunity and limits melanoma growth
· bioRxiv (Cold Spring Harbor Laboratory)
2026 ANIMAL
Simulated poultry-house PM 2.5 exposure reveals a gut–lung axis mechanism of microbial propionate in protecting against pneumonia
· Applied and Environmental Microbiology
2026 OTHER
P0128 Targeting the ‘Gut Microbiota-Diet-Immunometabolism’ Axis for the Alleviation of Ulcerative Colitis
· Journal of Crohn s and Colitis
2026 META_ANALYSIS
Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome
· Advanced Science
2026 OTHER
Tu1536 BACTEROIDES UNIFORMIS AMELIORATES INTESTINAL FIBROSIS AND IMPROVES SERUM METABOLITES PROFILES IN CROHN’S DISEASE
· Gastroenterology
2025 IN_VITRO
Selective utilization of medicinal polysaccharides by human gut Bacteroides and Parabacteroides species
· Nature Communications
2025 OTHER
Bacteroides uniformis Eggerth and Gagnon 1933 emend. Hahnke et al. 2016
· BacDive
2025 ANIMAL
B.uniformis IM01-derived IAA alleviates asthma via AhR/NLRP3 pathways in mice
· Cellular and Molecular Life Sciences
2025 ANIMAL
Impact of bacteroides uniformis on fatty liver hemorrhagic syndrome in dawu golden phoenix laying hens: modulation of gut microbiota and arachidonic acid metabolism
· Frontiers in Microbiology
2025 WGS
A toolkit for transposon libraries and functional genomics in intestinal Bacteroidales
· bioRxiv (Cold Spring Harbor Laboratory)
2025 IN_VITRO
Prebiotic Effect of Oxidized Hydroxypropyl Starch via In Vitro and In Vivo
· Foods
2025 OBSERVATIONAL
Correlation Between Gastroesophageal Reflux Disease and Small Intestinal Bacterial Overgrowth: Analysis of Intestinal Microbiome and Metabolic Characteristics
· Journal of Inflammation Research
2025 ANIMAL
Bacteroides uniformis-generated hexadecanedioic acid ameliorates metabolic-associated fatty liver disease
· Gut Microbes
Browse all 540 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    4-Hydroxyphenanthrene exacerbates obesity by altering gut microbiota and bile acid metabolism
    · Nature Communications · 2026
    PMID 41826291 →
  2. [2]
    Tryptophan degradation by intestinal Bacteroides induces anti-tumor immunity and limits melanoma growth
    · bioRxiv (Cold Spring Harbor Laboratory) · 2026
    PMID 42182364 →
  3. [3]
    Persea americana for Total Health (PATH-2): Effects of Avocado Consumption on Gastrointestinal Health in a Randomized, Crossover, Complete Feeding Trial
    · medRxiv · 2026
    Source →
  4. [4]
    Causal Relationship Between Gut Microbiota, Serum Metabolites and Inflammatory Bowel Disease: A Mendelian Randomization Study
    · Jundishapur Journal of Microbiology · 2025
    Source →
  5. [5]
    Bacteroides uniformis and its preferred substrate, α-cyclodextrin, enhance endurance exercise performance in mice and human males
    · Science Advances · 2023
    PMID 36696509 →