Strain Profile · NCBI Species Taxon 1694
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Bifidobacterium pseudolongum

◔ Human-origin
Sequenced
Public genome assembly available

Bifidobacterium pseudolongum is a species found in the intestinal microbiota of various mammals, including rodents and swine, where it has attracted growing research interest as a potential probiotic candidate. Animal model studies have examined B. pseudolongum enrichment during fasting-mimicking diet conditions in a colorectal cancer mouse model in relation to immune memory responses, and separate work has examined possible roles in liver injury and intestinal barrier signaling pathways. These findings derive exclusively from animal experiments; no human clinical trials have been conducted. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 213 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+4 more systems

Symptoms in the research

Share of this strain's 55 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+4 more symptoms

Research

409 papers reference this strain in the probiotic database.

Match confidence
2026 ANIMAL
Polygonatum cyrtonema Polysaccharides‐Derived Metabolic Meta Alleviates ALD via a Gut–Liver Axis–Mediated, Bifidobacterium pseudolongum–Driven Suppression of the AA Metabolism–MAPK Signaling Network
· Food Frontiers
2026 ANIMAL
SAT-356 Bifidobacterium pseudolongum-derived inosine mitigates polystyrene nanoplastics-induced hepatic injury by inhibiting the polarization of M1 macrophages
· Journal of Hepatology
2026 ANIMAL
Bifidobacterium pseudolongum alleviates chronic intermittent hypoxia-induced cognitive impairment by restoring acetate metabolism and suppressing hippocampal neuroinflammation and neuronal PANoptosis
· Microbiological Research
2026 ANIMAL
Bifidobacterium strains as potential probiotics for poultry: Early contributions to broiler development
· German Journal of Veterinary Research
2026 ANIMAL
Host-helminth-microbiome interactions: infection with Hymenolepis diminuta and the regulation of colitis
· University of Calgary
2026 ANIMAL
Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization
· Advanced Science
2026 ANIMAL
Bifidobacterium pseudolongum enriched by arctigenin orchestrates cough variant asthma via the acetate-aryl hydrocarbon receptor-interleukin-33 axis
· Journal of Pharmaceutical Analysis
2026 ANIMAL
Administering Bifidobacterium pseudolongum With Arsenic Trioxide Attenuates Acute Promyelocytic Leukemia in Mice by Restoring Immune Microenvironment and Intestinal Homeostasis
· Frontiers in Bioscience-Landmark
2026 ANIMAL
Fructooligosaccharides and ellagic acid synergistically enhance muscular endurance via targeting gut microbial urolithin A biosynthesis
· Journal of Advanced Research
2025 OBSERVATIONAL
Identification of fecal microbes as potential biomarkers for early diagnosis of fatty liver disease in cattle
· Virulence
2025 ANIMAL
423 Lactulose modulates the gut microbiota to potentiate anti-tumor immunity and enhance anti-PD-L1 efficacy
· Regular and Young Investigator Award Abstracts
2025 ANIMAL
Shaping the gut microbiota of tumour-induced mice with an innovative mixture of dietary fibres designed for food for oncological medical purpose
· Journal of Future Foods
2025 ANIMAL
Gut Microbiota–Decanoic Acid–Interleukin-17A Axis Orchestrates Hyperglycemia-Induced Osteoporosis in Male Mice
· Diabetes
2025 ANIMAL
Cholesterol-Lowering Mechanism of Lactobacillus Bile Salt Hydrolase through Regulation of Bifidobacterium pseudolongum in the Gut Microbiota
· Preprints.org
2025 ANIMAL
Cholesterol-Lowering Mechanism of Lactobacillus Bile Salt Hydrolase Through Regulation of Bifidobacterium pseudolongum in the Gut Microbiota
· Nutrients
2025 ANIMAL
Fasting-mimicking diet-enriched Bifidobacterium pseudolongum suppresses colorectal cancer by inducing memory CD8 + T cells
· Gut
2025 RCT
Time‐restricted feeding mitigates Alzheimer's disease‐associated cognitive impairments via a B. pseudolongum‐propionic acid‐FFAR3 axis
· iMeta
2025 ANIMAL
Aged Gut Microbiota Contributes to Cognitive Impairment and Hippocampal Synapse Loss in Mice
· Aging Cell
2025 ANIMAL
Gut Microbiota-Decanoic Acid-Interleukin-17A Axis Orchestrates Hyperglycemia-Induced Osteoporosis in Male Mice
·
2024 ANIMAL
Indole-3-acetic acid alleviates DSS-induced colitis by promoting the production of R-equol from Bifidobacterium pseudolongum
· Gut Microbes
Browse all 409 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Aged Gut Microbiota Contributes to Cognitive Impairment and Hippocampal Synapse Loss in Mice
    · Aging Cell · 2025
    PMID 40219707 →
  2. [2]
    423 Lactulose modulates the gut microbiota to potentiate anti-tumor immunity and enhance anti-PD-L1 efficacy
    · Regular and Young Investigator Award Abstracts · 2025
    Source →
  3. [3]
    Fasting-mimicking diet-enriched Bifidobacterium pseudolongum suppresses colorectal cancer by inducing memory CD8 + T cells
    · Gut · 2025
    PMID 39870395 →
  4. [4]
    Gut Microbiota–Decanoic Acid–Interleukin-17A Axis Orchestrates Hyperglycemia-Induced Osteoporosis in Male Mice
    · Diabetes · 2025
    PMID 41144501 →
  5. [5]
    Time‐restricted feeding mitigates Alzheimer's disease‐associated cognitive impairments via a B. pseudolongum‐propionic acid‐FFAR3 axis
    · iMeta · 2025
    PMID 40236783 →
  6. [6]
    Bifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma
    · Journal of Hepatology · 2023
    PMID 37459922 →
  7. [7]
    IDDF2022-ABS-0075 Bifidobacterium pseudolongum and its generated acetate suppress non-alcoholic fatty liver disease-associated hepatocellular carcinoma
    · · 2022
    Source →
  8. [8]
    Protective Effects of a Novel Probiotic Bifidobacterium pseudolongum on the Intestinal Barrier of Colitis Mice via Modulating the Pparγ/STAT3 Pathway and Intestinal Microbiota
    · Foods · 2022
    PMID 35681301 →
  9. [9]
    Meconium microbiome associates with the development of neonatal jaundice
    · Clinical and Translational Gastroenterology · 2018
    PMID 30237489 →
  10. [10]
    Gut Microbiota Determines Graft Survival Outcome Through Regulation of Anti-Inflammatory and Pro-Inflammatory Responses
    · Transplantation · 2018
    Source →