Strain Profile
· NCBI Species Taxon
1582
NCBI Taxonomy's node for this strain's species, not for the strain itself — NCBI has no strain-level node for it. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Lacticaseibacillus casei
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lacticaseibacillus casei (species-level entry, no specific strain designation) is a broad species grouping that includes well-studied commercial strains such as L. casei Shirota. The papers linked to this entry are heterogeneous, spanning food fermentation, spectroscopic characterization, folate assay methods, and a 2023 RCT examining synbiotic therapy in hospitalized COVID-19 patients. Because the linked evidence does not consistently reference a single strain, and because many papers are methodological rather than clinical, strain-specific health claims cannot be drawn from this record. Species-level properties are not reliably predictive of individual strain behavior.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 1,988 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 684 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
6175 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
OTHER
2026
IN_VITRO
2026
ANIMAL
2026
OTHER
2026
IN_VITRO
2026
OTHER
2026
ANIMAL
2026
IN_VITRO
2026
OTHER
2026
IN_VITRO
2026
ANIMAL
2026
IN_VITRO
2026
OTHER
2026
OTHER
2026
IN_VITRO
2026
IN_VITRO
2026
OTHER
2026
OTHER
2026
OTHER
2026
IN_VITRO
Browse all 6,175 papers →
Expression of E. coli-Derived Fimbrial Adhesin Protein (FimH) Gene in Lactic Acid Bacteria and Functional Analysis of the Fusion Protein
乳酸菌でのE.coli由来の線毛アドヒジュンタンパク質 (FimH) 遺伝子発現と融合タンパク質の機能解析
· Institutional Repositories DataBase (IRDB)
A Cashew Nut-Based Fermented Beverage: Development, Characterization, Potential Functionality and Sensory Evaluation
· Processes
Myostatin inhibition with orally administered Lactobacillus casei expressing a modified human myostatin protein: functional benefits and translational potential in advanced Duchenne muscular dystrophy
· Frontiers in Neurology
Karakterisasi Fisikokimia dan Viabilitas Lactobacillus Casei pada Es Krim Probiotik dengan Substitusi Tepung Kulit Pisang Kepok
· Karimah Tauhid.
Hot air convective and infrared dried probiotic red grape pomace: Phytochemical and physico-chemical properties, cell viability and the in vitro digestion of anthocyanins
· Applied Food Research
Bacterial viability and metabolic profiles of Lacticaseibacillus casei AP and Pediococcus acidilactici BE under various thermal treatment conditions
· Frontiers in Food Science and Technology
Citric Acid–Cross‐Linked Mucoadhesive Pectin Microparticles for Buccal Delivery of Glycyrrhizin and Lactobacillus Casei: Formulation, Characterization, and Evaluation
· ChemistrySelect
Fermentation Effect on Volatile Evolution of Plant-Based Dry-Cured Sausages
· Foods
Characteristics of antioxidant peptides derived from casein hydrolysis products of Lactobacillus casei 1.0351 and exploration of their pathway of action by molecular docking
· SSRN Electronic Journal
Dual Oxygen-Partitioned Co-Culture Uncovers Microbe-Specific Epithelial Stress and Homeostatic Programs
· bioRxiv (Cold Spring Harbor Laboratory)
Biotransformation of Fruit-Based Matrices Through Probiotic Fermentation: Effects on Chemical Composition, Volatiles and Sensory Properties
· Food and Bioprocess Technology
Microbiological, antioxidant and metabolomics changes in fermented dairy products supplemented with Matzhu
· Food Science of Animal Resources
Characteristics of antioxidant peptides derived from casein hydrolysis products of Lactobacillus casei 1.0351 and exploration of their pathway of action by molecular docking
· International Dairy Journal
Functional fresh cheese and the impact of enrichment with royal jelly
· Springer Link (Chiba Institute of Technology)
Designing Sustainable Probiotic Almond Spreads through Ultrasound, Lactic Fermentation, and Microencapsulation: A New Approach to Functional Plant-Based Foods
· ACS Food Science & Technology
Impact of pitaya pulp addition on cashew nut extract-based probiotic fermented beverages
· Letters in Applied Microbiology
The original dataset of the NSCLC project
· Mendeley Data
Revisiting lactic acid isomer production by lactic acid bacteria: Assessing process parameters and feedstock selection
· Biofuels Bioproducts and Biorefining
Extracellular vesicles and their RNA cargo facilitate bidirectional cross-kingdom communication between human and bacterial cells
· Gut Microbes
Fermented beverages enriched with quinoa or chestnut–persimmon: Nutritional, functional, and anti-nutritional assessment
· LWT
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 41221154 →Lactobacillus casei ’s Antitumor Potential in Colorectal Cancer: Exploring Mechanisms—A Systematic Review· BioMed Research International · 2025
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[2]
PMID 38954305 →Effect of Lacticaseibacillus casei LC2W Supplementation on Glucose Metabolism and Gut Microbiota in Subjects at High Risk of Metabolic Syndrome: A Randomized, Double-blinded, Placebo-controlled Clinical Trial· Probiotics and Antimicrobial Proteins · 2024
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[3]
PMID 39485259 →Oral administration of Lactobacillus casei DG® after ileostomy closure in restorative proctocolectomy: a randomized placebo-controlled trial (microbiota and immune microenvironment in pouchitis-MEP1)· Gut Microbes · 2024
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[4]
PMID 39610194 →Polyphenol‐Scaffolded Modular Assembly of Heterotypic Cell–Cell Assemblies for Potentiating Cancer Immunotherapy· Small · 2024
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[5]
Source →The effectiveness of the use of synbiotics in the complex therapy of acute intestinal infections in children· Russian Pediatric Journal · 2023
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[6]
PMID 38205053 →Evaluation of the Probiotic Properties of Lacticaseibacillus casei 431® Isolated from Food for Special Medical Purposes· Food Technology and Biotechnology · 2023
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[7]
PMID 37604396 →The efficacy of combined arginine and probiotics as an add-on to 1450 ppm fluoride toothpaste to prevent and control dental caries in children – A randomized controlled trial· Journal of Dentistry · 2023
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[8]
PMID 36856122 →Agave fructans enhance the effects of fermented milk products on obesity biomarkers: a randomised trial· Beneficial Microbes · 2023
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[9]
PMID 37311176 →Antiobesity Effects of Lactobacillus paracasei Subsp. paracasei, L. casei 431 on High-Fat Diet-Induced Obese Rats· Journal of Medicinal Food · 2023
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[10]
PMID 37356561 →The effect of a lozenge combining prebiotic arginine and probiotics on caries increment in children during 10–12 months, a randomized clinical trial· Journal of Dentistry · 2023