Strain Profile
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Lactobacillus acidophilus L-92
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus acidophilus L-92 has been studied with a focus on allergic conditions, including atopic dermatitis (eczema) and allergic rhinitis (hay fever). Multiple Japanese randomized controlled trials, some using heat-killed rather than live cells, have examined symptom scores for seasonal and perennial allergic rhinitis and atopic dermatitis severity in adults and children. In vitro studies have examined the strain's influence on immune cell gene expression in the context of allergy research. The trials are mostly from a single research tradition and used varying preparations, so independent replication remains an important next step. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 38 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 18 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
40 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
RCT
2021
RCT
2020
RCT
2020
IN_VITRO
2019
RCT
2019
RCT
2018
RCT
2018
RCT
2018
RCT
2018
RCT
2018
RCT
2017
RCT
2016
RCT
2016
IN_VITRO
2016
RCT
2014
IN_VITRO
2014
IN_VITRO
2014
ANIMAL
2014
IN_VITRO
2013
IN_VITRO
Browse all 40 papers →
Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult atopic dermatitis patients
· Institutional Repositories DataBase (IRDB)
Effects of Lactobacillus acidophilus L-92 Intake on Immune Indicators and Subjective Symptoms Related to Physical Condition in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparative Study
Lactobacillus acidophilus L—92 摂取による健常者の免疫指標と体調変化に関する自覚症状への影響について―ランダム化二重盲検プラセボ対照並行群間比較試験―
· 薬理と治療
Industrial Reports: Alleviation of Pollinosis Symptoms by Intake of Foods Containing Lactobacillus acidophilus L-92
Industrial Reports : Lactobacillus acidophilus L-92含有食品摂取による花粉症症状緩和効果
· アグリバイオ = Agricultural biotechnology
Functional role of surface layer proteins of Lactobacillus acidophilus L-92 in stress tolerance and binding to host cell proteins
· Bioscience of Microbiota Food and Health
Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy
· Asia Pacific Allergy
Effects of Intake of Foods Containing Lactobacillus acidophilus L-92 on Subjects with Pollinosis
Lactobacillus acidophilus L-92含有食品摂取による花粉症有症者に対する影響
·
The Effects of Oral Administration of Lactobacillus acidophilus L-92 on the Symptoms of Pollen Allergy-A randomized, Double-blind, Placebo-controlled, Parallel-group Study-
· 薬理と治療
Efficacy of Heat-Killed Lactobacillus acidophilus L-92 in Subjects with Mild to Moderate Perennial Allergic Rhinitis: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Study
加熱殺菌体Lactobacillus acidophilus L-92の軽症から中等症の通年性アレルギー性鼻炎有症者に対する有効性-ランダム化プラセボ対照二重盲検並行群間比較試験-
· 薬理と治療
Safety of Excessive Intake of Foods Containing Heat-Killed Lactobacillus acidophilus L-92 in Healthy Subjects: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Study
加熱殺菌体Lactobacillus acidophilus L—92 株を含有する食品の健常人に対する過剰摂取時の安全性―ランダム化プラセボ対照二重盲検並行群間比較試験―
· 薬理と治療
Efficacy of Heat-Killed Lactobacillus acidophilus L-92 in Subjects with Mild to Moderate Perennial Allergic Rhinitis: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Study
加熱殺菌体Lactobacillus acidophilus L—92 の軽症から中等症の通年性アレルギー性鼻炎有症者に対する有効性―ランダム化プラセボ対照二重盲検並行群間比較試験―
· 薬理と治療
Effects of Intake of Foods Containing Lactobacillus acidophilus L-92 on Subjects with Pollinosis: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study
Lactobacillus acidophilus L—92含有食品摂取による花粉症有症者に対する影響―ランダム化プラセボ対照二重盲検並行群間試験―
· 薬理と治療
Effects of Lactobacillus acidophilus L-92 Intake on Upper Respiratory Subjective Symptoms and Immune Parameters in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparative Study
健常者におけるLactobacillus acidophilus L—92摂取による上気道の自覚症状と免疫パラメーターへの影響について―無作為化二重盲検プラセボ対照並行群間比較試験―
· 薬理と治療
Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis
· Journal of Dairy Science
Effects of Lactic Acid Bacterium Lactobacillus acidophilus L-92 on the Intestinal Immune System and Analysis of Related Molecules
乳酸菌Lactobacillus acidophilus L-92株の腸管免疫系への作用と関連分子の解析
· Institutional Repositories DataBase (IRDB)
Efficacy of Continuous Intake of Lactobacillus acidophilus L-92 in Adult Patients with Atopic Dermatitis
アトピー性皮膚炎の成人患者におけるアシドフィルス菌Lactobacillus acidophilus L‐92の持続性摂取の有効性
· Journal of Dairy Science
Lactobacillus acidophilus L-92 cells activate expression of immunomodulatory genes in THP-1 cells.
· Institutional Repositories DataBase (IRDB)
Lactobacillus acidophilus L-92 Cells Activate Expression of Immunomodulatory Genes in THP-1 Cells
· Bioscience of Microbiota Food and Health
Excretion of 3,3’,4,4’,5-Pentachlorobiphenyl (PCB126) from Rat Liver Following Oral Administration of Lactobacillus reuteri and Lactobacillus acidophilus
· Food Science and Technology Research
Lactobacillus acidophilus L-92 Cells Activate Expression of Immunomodulatory Genes in THP-1 Cells
· Bioscience of Microbiota Food and Health
Anti-influenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity.
· Institutional Repositories DataBase (IRDB)
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Citations
Selected papers that name this strain.
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[1]
Source →Effects of Lactobacillus acidophilus L-92 Intake on Immune Indicators and Subjective Symptoms Related to Physical Condition in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparative StudyLactobacillus acidophilus L—92 摂取による健常者の免疫指標と体調変化に関する自覚症状への影響について―ランダム化二重盲検プラセボ対照並行群間比較試験―· 薬理と治療 · 2021
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[2]
PMID 31089460 →Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy· Asia Pacific Allergy · 2019
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[3]
Source →Efficacy of Heat-Killed Lactobacillus acidophilus L-92 in Subjects with Mild to Moderate Perennial Allergic Rhinitis: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Study加熱殺菌体Lactobacillus acidophilus L—92 の軽症から中等症の通年性アレルギー性鼻炎有症者に対する有効性―ランダム化プラセボ対照二重盲検並行群間比較試験―· 薬理と治療 · 2018
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[4]
Source →Effects of Intake of Foods Containing Lactobacillus acidophilus L-92 on Subjects with Pollinosis: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group StudyLactobacillus acidophilus L—92含有食品摂取による花粉症有症者に対する影響―ランダム化プラセボ対照二重盲検並行群間試験―· 薬理と治療 · 2018
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[5]
Source →Safety of Excessive Intake of Foods Containing Heat-Killed Lactobacillus acidophilus L-92 in Healthy Subjects: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Study加熱殺菌体Lactobacillus acidophilus L—92 株を含有する食品の健常人に対する過剰摂取時の安全性―ランダム化プラセボ対照二重盲検並行群間比較試験―· 薬理と治療 · 2018
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[6]
Source →Effects of Lactobacillus acidophilus L-92 Intake on Upper Respiratory Subjective Symptoms and Immune Parameters in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparative Study健常者におけるLactobacillus acidophilus L—92摂取による上気道の自覚症状と免疫パラメーターへの影響について―無作為化二重盲検プラセボ対照並行群間比較試験―· 薬理と治療 · 2017
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[7]
PMID 27108169 →Efficacy of prolonged ingestion of Lactobacillus acidophilus L-92 in adult patients with atopic dermatitis· Journal of Dairy Science · 2016
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[8]
Source →Excretion of 3,3’,4,4’,5-Pentachlorobiphenyl (PCB126) from Rat Liver Following Oral Administration of Lactobacillus reuteri and Lactobacillus acidophilus· Food Science and Technology Research · 2014
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[9]
Source →Anti-allergic effects of Lactobacillus acidophilus L-92 strain.· Japanese Journal of Lactic Acid Bacteria · 2010