Strain Profile
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Lactobacillus gasseri PA 16/8

◐ Food-origin
Sequenced
Public genome assembly available

Lactobacillus gasseri PA 16/8 is best known as one component of the BION 3 multi-strain supplement (together with B. bifidum M 20/5 and B. longum SP 07/3). A 2005 double-blind RCT examined the combination in relation to duration of common cold episodes in healthy adults, though the study cannot distinguish the contribution of this individual strain. Reviews on respiratory immune defense have discussed this combination, and a 2012 EFSA scientific opinion examined the associated health claim but concluded the evidence was insufficient to substantiate it at the EU regulatory level. Strain-specific human evidence for PA 16/8 alone is limited; most data come from the multi-strain product context. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 7 body-system-tagged papers that concern each system. Research coverage, not measured effect.

Symptoms in the research

Share of this strain's 3 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

Research

7 papers reference this strain in the probiotic database.

Match confidence
2019 IN_VITRO
Probiotic survival during a multi‐layered tablet development as tested in a dynamic, computer‐controlled in vitro model of the stomach and small intestine (TIM‐1)
· Letters in Applied Microbiology
2016 REVIEW
Oral probiotics as anti-infectious immune response stimulators in the respiratory tract
· Terapevticheskii arkhiv
2016 REVIEW
Oral probiotics as stimulators of anti-infective immune responses in the respiratory tract
Пероральные пробиотики как стимуляторы противоинфекционного иммунного ответа в респираторном тракте
· Terapevticheskii arkhiv
2014 OBSERVATIONAL
BION 3 IN PREVENTION OF POSTOPERATIVE COMPLICATIONS AND CORRECTION OF IMMUNE SYSTEM AND GUT MICROBIOTA DISORDERS IN PATIENTS WITH COLORECTAL CANCER
· CyberLeninK (CyberLeninka)
2012 REVIEW
Scientific Opinion on the substantiation of health claims related to a combination of Lactobacillus gasseri PA 16/8, Bifidobacterium bifidum M 20/5 and Bifidobacterium longum SP 07/3 and maintenance of upper respiratory tract defence against pathogens (ID 931, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
· EFSA Journal
2010 IN_VITRO
Pengaruh Pemberian Glukosa pada Fyltrat Bakteri Probiotik terhadap Pertumbuhan Salmonela typhi Secara In-Vitro
·
2005 RCT
Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: A double blind, randomized, controlled trial
· Clinical Nutrition
Browse all 7 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Probiotic survival during a multi‐layered tablet development as tested in a dynamic, computer‐controlled in vitro model of the stomach and small intestine (TIM‐1)
    · Letters in Applied Microbiology · 2019
    PMID 31454425 →
  2. [2]
    Oral probiotics as anti-infectious immune response stimulators in the respiratory tract
    · Terapevticheskii arkhiv · 2016
    PMID 27458629 →
  3. [3]
    Oral probiotics as stimulators of anti-infective immune responses in the respiratory tract
    Пероральные пробиотики как стимуляторы противоинфекционного иммунного ответа в респираторном тракте
    · Terapevticheskii arkhiv · 2016
    Source →
  4. [4]
    BION 3 IN PREVENTION OF POSTOPERATIVE COMPLICATIONS AND CORRECTION OF IMMUNE SYSTEM AND GUT MICROBIOTA DISORDERS IN PATIENTS WITH COLORECTAL CANCER
    · CyberLeninK (CyberLeninka) · 2014
    Source →
  5. [5]
    Scientific Opinion on the substantiation of health claims related to a combination of Lactobacillus gasseri PA 16/8, Bifidobacterium bifidum M 20/5 and Bifidobacterium longum SP 07/3 and maintenance of upper respiratory tract defence against pathogens (ID 931, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
    · EFSA Journal · 2012
    Source →
  6. [6]
    Pengaruh Pemberian Glukosa pada Fyltrat Bakteri Probiotik terhadap Pertumbuhan Salmonela typhi Secara In-Vitro
    · · 2010
    Source →